ID   A0A024TYL2_9STRA        Unreviewed;      1549 AA.
AC   A0A024TYL2;
DT   09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT   09-JUL-2014, sequence version 1.
DT   24-JAN-2024, entry version 34.
DE   RecName: Full=Sister chromatid cohesion protein {ECO:0000256|RuleBase:RU364107};
GN   ORFNames=H310_08001 {ECO:0000313|EMBL:ETV99255.1};
OS   Aphanomyces invadans.
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Saprolegniales; Saprolegniaceae;
OC   Aphanomyces.
OX   NCBI_TaxID=157072 {ECO:0000313|EMBL:ETV99255.1};
RN   [1] {ECO:0000313|EMBL:ETV99255.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NJM9701 {ECO:0000313|EMBL:ETV99255.1};
RG   The Broad Institute Genomics Platform;
RA   Russ C., Tyler B., van West P., Dieguez-Uribeondo J., Young S.K., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L., Chapman S.B.,
RA   Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C.,
RA   Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C., Pearson M.,
RA   Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S., Wortman J.,
RA   Nusbaum C., Birren B.;
RT   "The Genome Sequence of Aphanomyces invadans NJM9701.";
RL   Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC       ECO:0000256|RuleBase:RU364107}.
CC   -!- SIMILARITY: Belongs to the SCC2/Nipped-B family.
CC       {ECO:0000256|ARBA:ARBA00009252, ECO:0000256|RuleBase:RU364107}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; KI913967; ETV99255.1; -; Genomic_DNA.
DR   RefSeq; XP_008871811.1; XM_008873589.1.
DR   STRING; 157072.A0A024TYL2; -.
DR   EnsemblFungi; H310_08001-t26_3; H310_08001-t26_3-p1; H310_08001.
DR   EnsemblProtists; ETV99255; ETV99255; H310_08001.
DR   GeneID; 20085051; -.
DR   VEuPathDB; FungiDB:H310_08001; -.
DR   eggNOG; KOG1020; Eukaryota.
DR   OrthoDB; 77639at2759; -.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003682; F:chromatin binding; IEA:InterPro.
DR   GO; GO:0061780; P:mitotic cohesin loading; IEA:InterPro.
DR   GO; GO:0010468; P:regulation of gene expression; IEA:InterPro.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR026003; Cohesin_HEAT.
DR   InterPro; IPR024986; Nipped-B_C.
DR   InterPro; IPR033031; Scc2/Nipped-B.
DR   PANTHER; PTHR21704:SF18; NIPPED-B-LIKE PROTEIN; 1.
DR   PANTHER; PTHR21704; NIPPED-B-LIKE PROTEIN DELANGIN SCC2-RELATED; 1.
DR   Pfam; PF12765; Cohesin_HEAT; 1.
DR   Pfam; PF12830; Nipped-B_C; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
PE   3: Inferred from homology;
KW   Cell cycle {ECO:0000256|ARBA:ARBA00023306, ECO:0000256|RuleBase:RU364107};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU364107};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737, ECO:0000256|RuleBase:RU364107}.
FT   DOMAIN          1200..1380
FT                   /note="Sister chromatid cohesion C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF12830"
FT   REGION          88..129
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          136..155
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1518..1549
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1549 AA;  172525 MW;  31CBCB175EE66341 CRC64;
     MSNGLPLYIP REDGEDGNTS IWEMPPAPIT YANLPPVEAS RLNLASLNNL LSNVPLSLLP
     DHNPPAVLWD TMSPLLRAVV TDVHVLSPNV QRPQPPSKKH KTSAPVYDLT TPEHNHQRSS
     NDATKGHRLP RAKVIEIADE DDDGPSTPLA GDTQESKKKA IVQKYEDELH GLLGCLSTAP
     EVSRVMKKIM QTMQLLHKSH KELIQHLSFD LLGDLMSLLD TRVTDALTID LFAVAYANNG
     DADWEVSGID YNKLNDIVCA MDAASCMLYI MTSPNIDRRL LSEEYIEHCI SLLKHVLQRL
     LCPSLDNLSL SKLLQESKSS VHPKYHGALK KKIDKVGLVH ILSTYLETIE ELVTGIKLQD
     SWILTLSNAL IDTFSLEGSQ ATQANICLLQ VRASGLFRGI FLHYPTHRAL LIDDIFSVLL
     KLPSNKRNLR TFKLSHGDIQ VQMISMLLVT LVQSCVRVSL ENVREAARVI VHSFVQKCMK
     KEESNDCRQT FENFVDDLLV MLTSPEWPAV QLILESLSGG LTSLMAQQKA NKLESQTSLL
     ALHLLGKICA TIRQITCEAN AQPIQEMKHP PALVECREQA IQLLASKQVQ ITKANLVECM
     VLMHLGEQST HMCVDAEVFH RAQCSFSDEF ISLKANVTLT GTMGRLLVTE LVSHRELCQH
     FDQMLMAIMA FLTRGQPTFR ARVLKALMMI VDSDPLLMGD DHLHQAITLS LSDEATSVRQ
     SAVELVGKYI GLQPMLFPKY FAMLADRLRD KGISVRKSVL RIFKVYLQYT TIEPTVAESV
     SKALRALVER IGIASEEESV KDTVLSTLQD VWFGARPTPP SNRRGQSNQE TTVTPSCLRK
     KSTNNYKVLS MIDVVHHVHN PEWMVALICR LIKKNADEME TACSTMVSEL MEFLLQLEEG
     HALPLLSFDD KEAQRLATLK TLHVICEASP KMVLPYLDTL TVYLKQDDRL SKPTQMHVLA
     MAAAMIGLVI PCVEKPVEKW MVALENDLKS LVLGAPPQVV KPAVECLATL TTCANRQPKL
     LLKILEMLYT FLLRSEALIK LDKPISDKPN LLRSLFVAGL VAGSLEWGAL PHFSSAIFTK
     EKLVDMVYEV YERFCKVSNT HVHFDGALRV KTVQGLGYLL HKNPRILFKS QQDNTLRMTI
     LHQDPKVRAQ ILASLTELLQ AEEARLEKLH SQGSKQGKDY VQGDQEGDAS LIGGVMIAQL
     DDILKVAVQK EASIRSQAIA CIGLLLTQGL IPPMRCIPTL IALETDQVAF IRDAAHMHLV
     SIHGKFPNMV SGPAIQGIYS SYQFQTRAFG KSVVCDSENV CLLGRMYRAC FQGNRSQRHA
     FYNGLLGAFR EKGPMFTALA EKRLPVVAAL GYLIYVAQLL SVLPYDVEDE PLYLVYTINR
     DVSLGLGTVQ DKMKKFLGKD ASFDNLPVTD PVKPELVAVG HSAFGLALLV RLKMALKAAY
     LLDNEKCQTF QTTNTTKANE APVSRASLDT AILNVPDMVA DDVMNNSWLQ LKLLGNAASD
     DQAQLDFDWE NPQLTKKKGV KLHGKRGRKR KEKKADSGDD DDVQVDDIF
//