ID A0A024U0K3_9STRA Unreviewed; 322 AA.
AC A0A024U0K3;
DT 09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT 09-JUL-2014, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=TKL/DRK protein kinase, variant 1 {ECO:0000313|EMBL:ETV99798.1};
GN ORFNames=H310_07843 {ECO:0000313|EMBL:ETV99798.1};
OS Aphanomyces invadans.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Saprolegniales; Saprolegniaceae;
OC Aphanomyces.
OX NCBI_TaxID=157072 {ECO:0000313|EMBL:ETV99798.1};
RN [1] {ECO:0000313|EMBL:ETV99798.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NJM9701 {ECO:0000313|EMBL:ETV99798.1};
RG The Broad Institute Genomics Platform;
RA Russ C., Tyler B., van West P., Dieguez-Uribeondo J., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L., Chapman S.B.,
RA Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C.,
RA Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C., Pearson M.,
RA Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S., Wortman J.,
RA Nusbaum C., Birren B.;
RT "The Genome Sequence of Aphanomyces invadans NJM9701.";
RL Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the protein kinase superfamily.
CC {ECO:0000256|RuleBase:RU000304}.
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DR EMBL; KI913966; ETV99798.1; -; Genomic_DNA.
DR RefSeq; XP_008871574.1; XM_008873352.1.
DR AlphaFoldDB; A0A024U0K3; -.
DR EnsemblFungi; H310_07843-t26_1; H310_07843-t26_1-p1; H310_07843.
DR EnsemblProtists; ETV99798; ETV99798; H310_07843.
DR GeneID; 20084893; -.
DR VEuPathDB; FungiDB:H310_07843; -.
DR OrthoDB; 20877at2759; -.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd13999; STKc_MAP3K-like; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR44329:SF313; MIXED LINEAGE KINASE DOMAIN-LIKE PROTEIN; 1.
DR PANTHER; PTHR44329; SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED; 1.
DR Pfam; PF07714; PK_Tyr_Ser-Thr; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Kinase {ECO:0000313|EMBL:ETV99798.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU10141};
KW Serine/threonine-protein kinase {ECO:0000256|ARBA:ARBA00022527,
KW ECO:0000256|RuleBase:RU000304}; Transferase {ECO:0000313|EMBL:ETV99798.1}.
FT DOMAIN 103..322
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REGION 1..31
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 16..31
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 130
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 322 AA; 35663 MW; AB046ACE3A3946D0 CRC64;
MGCGSSKGTS DVYEPVLPPA PEPVPVPAPA TEPNAIQAPA PVAVQEVVAA PTIDASLTKP
KPLLPQPGTV TFTEFKDGEK VVVDSILDSR IHLRMAAINF KELKLQKIIG QGAFGEVIKG
TYHGTPVVVK RMVRQKIDPE NIRMFADEIQ LMMNLRHPNI VQFIGASWNS YSNICFVTEF
LDRGDLYSVL KNPRVQLSWK QPLLSMAIDI SRGMAYLHSM DPPIIHRDLK SMNILVSSSF
GAKISDFGLS REKVLDDTMS VTGTPLWLPP EMIRAERYSE KADVYSFGIV LTELDTRRIP
YHDIKNVGTS KKRVSQHANS NV
//
