ID A0A024U1Z6_9STRA Unreviewed; 4212 AA.
AC A0A024U1Z6;
DT 09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT 09-JUL-2014, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE RecName: Full=AAA+ ATPase domain-containing protein {ECO:0000259|SMART:SM00382};
GN ORFNames=H310_07716 {ECO:0000313|EMBL:ETV99647.1};
OS Aphanomyces invadans.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Saprolegniales; Saprolegniaceae;
OC Aphanomyces.
OX NCBI_TaxID=157072 {ECO:0000313|EMBL:ETV99647.1};
RN [1] {ECO:0000313|EMBL:ETV99647.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NJM9701 {ECO:0000313|EMBL:ETV99647.1};
RG The Broad Institute Genomics Platform;
RA Russ C., Tyler B., van West P., Dieguez-Uribeondo J., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L., Chapman S.B.,
RA Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C.,
RA Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C., Pearson M.,
RA Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S., Wortman J.,
RA Nusbaum C., Birren B.;
RT "The Genome Sequence of Aphanomyces invadans NJM9701.";
RL Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KI913966; ETV99647.1; -; Genomic_DNA.
DR RefSeq; XP_008871423.1; XM_008873201.1.
DR STRING; 157072.A0A024U1Z6; -.
DR EnsemblFungi; H310_07716-t26_1; H310_07716-t26_1-p1; H310_07716.
DR EnsemblProtists; ETV99647; ETV99647; H310_07716.
DR GeneID; 20084766; -.
DR VEuPathDB; FungiDB:H310_07716; -.
DR eggNOG; KOG3595; Eukaryota.
DR OrthoDB; 312149at2759; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0030286; C:dynein complex; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0045505; F:dynein intermediate chain binding; IEA:InterPro.
DR GO; GO:0051959; F:dynein light intermediate chain binding; IEA:InterPro.
DR GO; GO:0008569; F:minus-end-directed microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR Gene3D; 1.10.287.2620; -; 1.
DR Gene3D; 1.10.472.130; -; 1.
DR Gene3D; 1.10.8.1220; -; 1.
DR Gene3D; 1.10.8.710; -; 1.
DR Gene3D; 1.20.1270.280; -; 1.
DR Gene3D; 1.20.58.1120; -; 1.
DR Gene3D; 1.20.920.20; -; 1.
DR Gene3D; 1.20.920.30; -; 1.
DR Gene3D; 3.10.490.20; -; 1.
DR Gene3D; 6.10.140.1060; -; 1.
DR Gene3D; 1.20.140.100; Dynein heavy chain, N-terminal domain 2; 1.
DR Gene3D; 3.20.180.20; Dynein heavy chain, N-terminal domain 2; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 5.
DR Gene3D; 1.10.8.720; Region D6 of dynein motor; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR035699; AAA_6.
DR InterPro; IPR035706; AAA_9.
DR InterPro; IPR041658; AAA_lid_11.
DR InterPro; IPR042219; AAA_lid_11_sf.
DR InterPro; IPR026983; DHC_fam.
DR InterPro; IPR041589; DNAH3_AAA_lid_1.
DR InterPro; IPR042222; Dynein_2_N.
DR InterPro; IPR043157; Dynein_AAA1S.
DR InterPro; IPR041466; Dynein_AAA5_ext.
DR InterPro; IPR041228; Dynein_C.
DR InterPro; IPR043160; Dynein_C_barrel.
DR InterPro; IPR024743; Dynein_HC_stalk.
DR InterPro; IPR024317; Dynein_heavy_chain_D4_dom.
DR InterPro; IPR004273; Dynein_heavy_D6_P-loop.
DR InterPro; IPR013602; Dynein_heavy_linker.
DR InterPro; IPR042228; Dynein_linker_3.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR025662; Sigma_54_int_dom_ATP-bd_1.
DR PANTHER; PTHR45703; DYNEIN HEAVY CHAIN; 1.
DR PANTHER; PTHR45703:SF34; DYNEIN HEAVY CHAIN, CYTOPLASMIC; 1.
DR Pfam; PF12774; AAA_6; 1.
DR Pfam; PF12775; AAA_7; 1.
DR Pfam; PF12780; AAA_8; 1.
DR Pfam; PF12781; AAA_9; 1.
DR Pfam; PF17857; AAA_lid_1; 1.
DR Pfam; PF18198; AAA_lid_11; 1.
DR Pfam; PF08393; DHC_N2; 1.
DR Pfam; PF17852; Dynein_AAA_lid; 1.
DR Pfam; PF18199; Dynein_C; 1.
DR Pfam; PF03028; Dynein_heavy; 1.
DR Pfam; PF12777; MT; 1.
DR SMART; SM00382; AAA; 4.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 4.
DR PROSITE; PS00675; SIGMA54_INTERACT_1; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Dynein {ECO:0000256|ARBA:ARBA00023017};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 1508..1646
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 1795..1940
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 2173..2331
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 2529..2686
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT REGION 1..65
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 92..141
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 442..467
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 703..730
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2994..3028
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 21..51
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 4212 AA; 470949 MW; 977E44011A957605 CRC64;
MADEVRAAAP PPGKKKPAPP PSTHATSSVP KRLSRILNLN DLRQESSGHA TPPTGALGVH
PPSGQTDKAL LVDRIYAKGI KRTLLQAQLF PPNKETGSKL SPFTLQPLVP PNPTEKALVP
RRPEPLHSPL SPTGNKGSLT ASRFVIPKSP PASVEPSPPT PLSARDAYYL DVRRPQAKKP
KFVSPPVAVP RQSTLSIQKP ADGVAPPTRA QLLQKSTQLK TFTESVEESI LTSGVPKDSF
LYLARAEDNP YKLVVVDHAA INVHDYYTMS RAGITHFCDG VPEFTYLETF EREHYMFSLV
REIPFFQKYR VWKQFRTWKT NVRAVKTALC KRVLTQDLFI LRPTLHGALM ELRTLCYNMG
LLRVFSIEAR RTYTLIEFSE CQQVQMTDTQ TRIGEFVKAI VDTTHTTCNA FLSDFLLSNG
FATPEKLPPN LASILALMGQ SASSEDDGQP PNKSPDDGHN ETKAVWQNGR AVTFTERAAM
RTQCRKITKL IRLVEFFVVD SFMLLGVVST QCLLEEMRRL ARVLASDIHN ALKPKHAPVA
TSPPTAPAGK QKLKLHAMPP PAVAPLFRVE IHLHLVPEHG SSFRSDLLFT PSCDELRAEL
ESVVFCGLKA ATKRDRLMSH TEFGPFVKPS LDEISNGELS AGLNLDMIVL EDSRFQAMTT
GIVDLITQSY DDLATFTQSL ATFQAEFIEN MTFRQVASNL TDATNLGRSI EDLRDQLDKY
TEQIARFDTL ADSAVVGLIL ADCRALNATL KPSPRQCMDA LHVLIPTIAQ HKNEDLMLEV
SKANDAISSI PTTVDEFAQA LASLRDTQSK MNGLDDRYMF LKMLYGLTDE YKIHVSDLDS
TNAFMLAQKR AQLKTSMDLL DTSTEAYTEK FSKELEKKIP KLTAQIQERL DELNDERLIS
ISSDASDMLA ILQGIHERLV EHEATSVKYV GFQRTLGLAQ SSFDELAVLR EDLEIKIQVW
KATKDWATQA DLWRDAAFAD ANVTALDEKI TAYFKIALTC ERSLPGNPVV HALKEAVESF
KETLPIVSDL RCPALQERHW QELTEVLHFD VMGDPTLTLG RLVDMKLQEF APSVNRIATE
ATQEKLLENM LMRITSLWAD LEFDIKSHND RKDLYVLGAT DDIVSALEES LINMNTILGS
RYVGPIRDDA VALHKRLVSF QETVDEWMAC QREWVYLETI FSAPDIQRQL PSEAQMFSVV
NTFWKDLMLK THDTPNCMKA TAAPGLCDTL VKHNHSLEKM RKSLEDYLET KRQSFPRFYF
LSNDELLEIL AHTKEPHAVQ PHLCKLFDAI MRLEFGDAHG SIDILSMNSA EGERVAFGRN
LKARGNIEDW LNAVQVSMTT SLHRSMKACV GDYEPAQRDS WIFHHPAQCV ASVTYMVWAK
ECEAAFGVPG GLEKWHKTIV SQLGGLTRLI RSPLTKLQRC IVTSLVTTDV HARDIVEELI
ELKVHAAHDF SWKKQLRYMW DADADDTVIQ QSNVTIHYGY EYMGACSRLV ITPLTDRCWM
TITGAFDLKL GASPSGPAGT GKTETSKDLA KALAIQCIVF NCSDQIDYKI MAKLFCGLSQ
CGCWTCLDEF NRIDIEVLSV IAQQLMILRH GRLAGTTDLC FEGRTILLQD HHVIVTMNPG
YAGRTELPDN LKICFRPVSM MVPDYSLIAE IMMFSEGFDN AKDLSKKITK LYKLCSEQLS
QQTHYDFGMR AVKTVLVMAG GMKRQQSNAA TGAAVTSEEL LLIRALREAN LPKFVDDDLV
LFLMIIRDLF PNVQVPEAQS SALEESIVQQ KRGMGYQDVP ALTRRTVELF ETLQVRSGVA
LTGCSGSGKT TCYTLLKKAM ADLRDDKQSA DRRFQKVTVH ALNPKSISLG ELYGSFHSLT
HEWKDGLASF LMRSIITDNA EIKGGPDKEV IPWLVFDGPI DALWIENLNT VLDDNMTLCL
ANGERIKLLP RMRLVFEVSD MNSASPASVS RLGVLYFSDK TLGWRPCIET WLCETFGTDI
DAKYGSTKLR GRVLKQLEAL LDEPWTYSFP LPLQTTFLSL VMNGCDLFTT LLHRQQKWFP
SADSDRQHKC LDMILVFAMG WAFGGNLFEN DQRQFNQLFI AWIADQKTLF VPSLMQVCGK
STGGAASCVG TGSSRTMACI FDFSIDFTEL AWSHWDNYVP AFAYQMHTPV FNIMVPTVDV
TKYSRLFSLL VAAMKPVFLT GDTGAGKTVI AHSVLDKLAA TGDIHGTGVI PVYVHFSAQT
TSATTQSSIE SKLIKKRKTL LGAPVSQKVV IFADDINLPA ADAYGTQPCI ELLRQLLDQK
GVYDREKYFW KDVSDTVITA AAGHPGGGRQ VLSQRFMRYF TVFSLPAGND DAMRVIFSAV
VQGHLHSLNF SPAVRDAATH VVDATISLYS AVSSELRPTP SKCHYLFNLR DVVKVFAGVL
TLRPSFSVDG TVKLWMHECL RVFCDRLVSK QDRTWFTTTL IQLVNKTFRM GWTHDGIFGS
DDAISVLFGC FGTGTVKEYD EIADIASLED LLNSFVDEYN SSHSTPLTLI FFRDTIMHVS
SMARILMQPR GNAMLIGVGG SGKRSLAKLA ASIMGHDCFE IELTRHYGRN EFREDLKTLL
VKTGVRGKDT MFLLTDTQLI SDEFVEDINS LLNAGEIPNL FTHEEFEAVM NDMKPILQQL
SLDDTRQNAE RSFVQRIRSH LHIVLCMSPV GSMFRSRCRQ FPSLINCTTM DWYEEWPTSA
LLCVAESYLN DVVLAAESSR KALAQMFVQV HHSIGRHTVL FRQVYQRHVY ITPKTYLDSI
RLYLRMLMEK RQQAKEAFDR LSTGVIKLED TNRIVAALQI ELTNLQPTLA AKAVEAEDLL
KQVSIDQKEA AIVEQKVSHD EAVVKAQAHE VSIIQADALK DLETAMPALN AAVQALDSLD
KKDITEVRSF AKPPQIVIVV MEAVCIMVGE KPDWDTAKKL LAKSTFMQEL KEYDKDNIPP
ATLKKIRKYT ESPEFAVEEV KKVSKAAMSL CMWIHAMDVY AKVVKEVGPK RDRLNQMNAV
LQDANGKLAK KQAELNEVIT RVRGLQAQCD SVVAEKKRLI MESDLTRERL KRAEKLTVGL
ADELVRWKAS MEKMVADELN LVGDVFLSAA SISYLGPFDC TFRAKLTHLW MLQCKELLPC
TPAFSLLDTC CDSVQLREWQ LHGLPTDSVS GENAIMLFRG DRWPLLIDPQ QQASTWIKRM
EQPFGLDVVK LHDKQLLRTV ETCVRDGHPL LLEDVQEVLD PALDTLLLKS LVKQGGKFML
RLGDKDVLYD RNFRLYMVTK LPNPHYLPDV CIKVNTINFT VTKEGLEDQL LGDVVRKEQP
DVELRKNTLL ASIANDQKIL KSIESKILAL LSNSQGNILD DQVLINTLAD SKQTATVVSE
RLAESEVTRA EISEIRNKYR GVSSRGSILY FVLADLAAVD PMYQYSLEYF SRLFNQSMDD
CVKVLGQHID ARVEMLIESQ MFLVYRNVCR GLFESHKLLF SLLISVRIAM EAAVVSPADV
ALLNPVVVDP LAIRPQELAD GHITSKQMGV VETLAASCFA MEGLPLSMHM YPEAWGQWIR
HDDPYCAAMP DDFDVKLTSF TKLVLVKALR QDRGIASAVS FIARSLGPQY TKSPPFVMAD
IFADLSKTVP CVFVLSSGAD PTSILHRFAQ SKQKDDALHV VSLGQGQGAV ASALIAQCAK
SGEWVLLQNC HLAKSWMPAL EHILHSLRVD PSDVHDDFRL FLTSFPATYF PIAILQSSVK
VTNEPPKGLK PNLLRSFEMV VTDDALSQCS KPAWRKLVFG LCFFHAVLQE RAKFGPIGWT
LSYHFNDSDL ETAMAVLRTF LDENDHIPWE ALHYVTGEIN YGGRVTDEFD RRCLLTNLQR
FYSAATVDDD APGRFFTTTS QVYFAPGYCT TASQFRDFIE LLPGHDAPGV FGLHENANIV
FQTQETNALF NTAMALQSRG ASASSTPVED NNDAIVLQLA VQVDANLPKL LERPASEMPP
PPTALMDSLT TVLGQEMVKF NALIRVVQLS VAQLQLAVKG VVTMSEALDS TYKSLLLKQV
PPEWHKVGFA SLKPLSSWLV DLVERVQFFR EWLEHGQPTT FPLPSFFFPQ GFLTGVLQNH
ARKHLVPINT LEFSFAIDPP DLVVADGAIV TGLFLEGGRW DGDRKVLTDA RPNEMLSVLP
PIHFLPNVAV THGQSKAGTW YDCPVYKTTA RRGTLSTTGI SSNYIISVHL PCDFTAAFWI
LNGTALIGNL NA
//
