ID   A0A024U349_9STRA        Unreviewed;       442 AA.
AC   A0A024U349;
DT   09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT   09-JUL-2014, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   RecName: Full=Serine aminopeptidase S33 domain-containing protein {ECO:0000259|Pfam:PF12146};
GN   ORFNames=H310_07240 {ECO:0000313|EMBL:ETW00679.1};
OS   Aphanomyces invadans.
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Saprolegniales; Saprolegniaceae;
OC   Aphanomyces.
OX   NCBI_TaxID=157072 {ECO:0000313|EMBL:ETW00679.1};
RN   [1] {ECO:0000313|EMBL:ETW00679.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NJM9701 {ECO:0000313|EMBL:ETW00679.1};
RG   The Broad Institute Genomics Platform;
RA   Russ C., Tyler B., van West P., Dieguez-Uribeondo J., Young S.K., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L., Chapman S.B.,
RA   Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C.,
RA   Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C., Pearson M.,
RA   Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S., Wortman J.,
RA   Nusbaum C., Birren B.;
RT   "The Genome Sequence of Aphanomyces invadans NJM9701.";
RL   Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the peptidase S33 family.
CC       {ECO:0000256|ARBA:ARBA00010088}.
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DR   EMBL; KI913964; ETW00679.1; -; Genomic_DNA.
DR   RefSeq; XP_008870814.1; XM_008872592.1.
DR   AlphaFoldDB; A0A024U349; -.
DR   EnsemblFungi; H310_07240-t26_1; H310_07240-t26_1-p1; H310_07240.
DR   EnsemblProtists; ETW00679; ETW00679; H310_07240.
DR   GeneID; 20084290; -.
DR   VEuPathDB; FungiDB:H310_07240; -.
DR   eggNOG; ENOG502SR96; Eukaryota.
DR   OrthoDB; 1941245at2759; -.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR022742; Hydrolase_4.
DR   PANTHER; PTHR43248; 2-SUCCINYL-6-HYDROXY-2,4-CYCLOHEXADIENE-1-CARBOXYLATE SYNTHASE; 1.
DR   PANTHER; PTHR43248:SF2; PROLYL AMINOPEPTIDASE; 1.
DR   Pfam; PF12146; Hydrolase_4; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..35
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          100..195
FT                   /note="Serine aminopeptidase S33"
FT                   /evidence="ECO:0000259|Pfam:PF12146"
SQ   SEQUENCE   442 AA;  48588 MW;  9083BE03B1124668 CRC64;
     MTLTLKAASK AFAAVILAPV AIAGFALFLA VWFVMTITFV GPLVQYCCNQ RDRKLLDRSR
     LCERVPDLQF IRIPHGNNCA GFDLAVRFTR STTSTTLPPV CIPNGLGASM TTISQLHEEL
     VKRGHTVLSY DRLGVGLSDR NTTGVSPTAD DVVKDMEFVL SSVLPPTTKW LVVGPSMGSI
     VGQYFVATYP NRVVAFLNMD GFPYPFCRRR AKFVLAGLIY KAYAAIIWTG VMRPFISMGI
     QSWRSRLQSA AFSIDVVRAE TNQANFFRNL AHEMITMIDL ADKVNAAWGS QSCLELSPAD
     LHTLAHTKPS AVGDVRDDGE WVPIDDSAIT DQLIPNYGTI EPAETAQAIA SLLARQPQSQ
     LAKTWQTLHV DVMSGRNFDY AGASMFIDDE MKDWYAAEHT IHALLAARGC RTVFPTKAHS
     DMFAMVQCIA DHVDKLSGAI DV
//