ID   A0A024UDU4_9STRA        Unreviewed;       586 AA.
AC   A0A024UDU4;
DT   09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT   09-JUL-2014, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   RecName: Full=Folate-Biopterin Transporter (FBT) Family {ECO:0008006|Google:ProtNLM};
GN   ORFNames=H310_03796 {ECO:0000313|EMBL:ETW04586.1};
OS   Aphanomyces invadans.
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Saprolegniales; Saprolegniaceae;
OC   Aphanomyces.
OX   NCBI_TaxID=157072 {ECO:0000313|EMBL:ETW04586.1};
RN   [1] {ECO:0000313|EMBL:ETW04586.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NJM9701 {ECO:0000313|EMBL:ETW04586.1};
RG   The Broad Institute Genomics Platform;
RA   Russ C., Tyler B., van West P., Dieguez-Uribeondo J., Young S.K., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L., Chapman S.B.,
RA   Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C.,
RA   Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C., Pearson M.,
RA   Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S., Wortman J.,
RA   Nusbaum C., Birren B.;
RT   "The Genome Sequence of Aphanomyces invadans NJM9701.";
RL   Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily. Folate-
CC       biopterin transporter (TC 2.A.71) family.
CC       {ECO:0000256|ARBA:ARBA00007015}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; KI913957; ETW04586.1; -; Genomic_DNA.
DR   RefSeq; XP_008866024.1; XM_008867802.1.
DR   AlphaFoldDB; A0A024UDU4; -.
DR   STRING; 157072.A0A024UDU4; -.
DR   EnsemblFungi; H310_03796-t26_1; H310_03796-t26_1-p1; H310_03796.
DR   EnsemblProtists; ETW04586; ETW04586; H310_03796.
DR   GeneID; 20080846; -.
DR   VEuPathDB; FungiDB:H310_03796; -.
DR   OrthoDB; 49634at2759; -.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR   InterPro; IPR039309; BT1.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   PANTHER; PTHR31585; FOLATE-BIOPTERIN TRANSPORTER 1, CHLOROPLASTIC; 1.
DR   PANTHER; PTHR31585:SF5; RIBOSOMAL_L9 DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF03092; BT1; 1.
DR   SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        79..96
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        116..136
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        233..252
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        272..291
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        321..342
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        354..372
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        384..405
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        449..474
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        494..512
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        532..557
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   586 AA;  64097 MW;  9F650ED36770DAF9 CRC64;
     MSAPDAANVM GHLGDVTRPF PLNSTRMRFV SNRDRDDAAS TDDYDPLKTP SQILDDSQHY
     YDGGAIRPGG PPKYTSPEIV ALLSQYVAVG LLYGALPNLA YPLFTAYFHL TGAQYNSATA
     LVSFGWTLKV FVGMLSDCVP ICGYRRKSWM MIGWSLCCTC MAVLSVMDHG PSYAALPATL
     DAVPANMEDR GARVAVLFAA ATISYIIADV PADALVVEVA QREPMASRGR MQSLIYTTRT
     VSSIFSQIVI GVCLNSPNYG GNFSWDMGMN SLFIMLAVAS ALMVPISFFF VQDIKQNGVY
     FSGYVRQFWE LVQRRATWQV MLFNFFFNLF ASGISSTAAP YVKLNWAKVE NLGTQLTTIA
     SNLIFAVVLA AMGKWGLEWN WRWVIVLTTL SMNVIDAAVQ YMTIYDVVRN QWFYLGVPVA
     EQLPYAMQFI VTTFVIVELA EVGNEGITYG LLTTVSNLPL VFGPILANVI FGGFRVDDKF
     IKADSPEART QVAYTYLIYY STTVFACVWV FLMPAQKAHV HELKVTGGKN PLIGGLVLFG
     CTAAMMWSVV VGILGVFEST NCLVIAGGQG CNKMMATAGG GSILTG
//