ID A0A024UIN3_9STRA Unreviewed; 582 AA.
AC A0A024UIN3;
DT 09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT 09-JUL-2014, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Delta l-pyrroline-5-carboxylate synthetase {ECO:0000313|EMBL:ETW06045.1};
GN ORFNames=H310_03643 {ECO:0000313|EMBL:ETW06045.1};
OS Aphanomyces invadans.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Saprolegniales; Saprolegniaceae;
OC Aphanomyces.
OX NCBI_TaxID=157072 {ECO:0000313|EMBL:ETW06045.1};
RN [1] {ECO:0000313|EMBL:ETW06045.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NJM9701 {ECO:0000313|EMBL:ETW06045.1};
RG The Broad Institute Genomics Platform;
RA Russ C., Tyler B., van West P., Dieguez-Uribeondo J., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L., Chapman S.B.,
RA Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C.,
RA Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C., Pearson M.,
RA Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S., Wortman J.,
RA Nusbaum C., Birren B.;
RT "The Genome Sequence of Aphanomyces invadans NJM9701.";
RL Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KI913956; ETW06045.1; -; Genomic_DNA.
DR RefSeq; XP_008865822.1; XM_008867600.1.
DR AlphaFoldDB; A0A024UIN3; -.
DR STRING; 157072.A0A024UIN3; -.
DR EnsemblFungi; H310_03643-t26_1; H310_03643-t26_1-p1; H310_03643.
DR EnsemblProtists; ETW06045; ETW06045; H310_03643.
DR GeneID; 20080693; -.
DR VEuPathDB; FungiDB:H310_03643; -.
DR eggNOG; KOG1154; Eukaryota.
DR eggNOG; KOG4165; Eukaryota.
DR OrthoDB; 314297at2759; -.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004349; F:glutamate 5-kinase activity; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0006561; P:proline biosynthetic process; IEA:UniProtKB-KW.
DR Gene3D; 3.40.1160.10; Acetylglutamate kinase-like; 1.
DR HAMAP; MF_00456; ProB; 1.
DR InterPro; IPR036393; AceGlu_kinase-like_sf.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR001048; Asp/Glu/Uridylate_kinase.
DR InterPro; IPR001057; Glu/AcGlu_kinase.
DR InterPro; IPR005715; Glu_5kinase/COase_Synthase.
DR InterPro; IPR019797; Glutamate_5-kinase_CS.
DR NCBIfam; TIGR01027; proB; 1.
DR PANTHER; PTHR11063:SF8; DELTA-1-PYRROLINE-5-CARBOXYLATE SYNTHASE; 1.
DR PANTHER; PTHR11063; GLUTAMATE SEMIALDEHYDE DEHYDROGENASE; 1.
DR Pfam; PF00696; AA_kinase; 1.
DR PRINTS; PR00474; GLU5KINASE.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR SUPFAM; SSF53633; Carbamate kinase-like; 1.
DR PROSITE; PS00902; GLUTAMATE_5_KINASE; 1.
PE 3: Inferred from homology;
KW Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00022605};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Proline biosynthesis {ECO:0000256|ARBA:ARBA00022650};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 16..264
FT /note="Aspartate/glutamate/uridylate kinase"
FT /evidence="ECO:0000259|Pfam:PF00696"
SQ SEQUENCE 582 AA; 61956 MW; 36063D84DB1F652A CRC64;
MPSQRNLARK DFVHAKRIVI KMGTSVVSTN GEPALGRLAS LVEQISMLKR QGKEVLLVTS
GSIGIGRKKL HKQLLLSASL RMHVQGGTAQ HHALDAKKGA MAAAGQVGLM ALYETLFSMY
DVACSQVLVT DAEFRTPEHR ANIRDTLLHL LEMDVLPIVN ENDAISAGLY RDDEGVFTDN
DSLAALIAGE TSANLLILLT DVDGVFDKPP SEPHAKVLSV FGASTSDGSI VFGEKSSVGR
GGMQAKIQSA NRAINQGVNA VVIASGFKYG ILDTIMKGAA VGTLFVPNPS ALMPANPPEE
MALAARDGSR ALLKLSSGER AAIVRRLARL LVDESPRILA ANQQDLDAAG STLDPQLRSR
LKLTHAKLVT LAQGIASVAD QEEPVGKVVS LMEISTGLVL EQVMTPIGVI LVVFESRPDS
LPQIAALALR SGNGLLLKGG REARHSNECL HALVQDAIRL EAHDKVSPAV IGLVTTRDDV
GALLALDHVV DLCIPRGSNA LVSHIKKHTR IPVLGHAEGG RRRQNRLPCR MQRTGKPCAG
RASCTARGAP SHTRRTRCGG RDVVCWSSGR KFELASRRAG GA
//
