ID   A0A024UIT3_9STRA        Unreviewed;       566 AA.
AC   A0A024UIT3;
DT   09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT   09-JUL-2014, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   RecName: Full=Transmembrane protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=H310_03456 {ECO:0000313|EMBL:ETW05772.1};
OS   Aphanomyces invadans.
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Saprolegniales; Saprolegniaceae;
OC   Aphanomyces.
OX   NCBI_TaxID=157072 {ECO:0000313|EMBL:ETW05772.1};
RN   [1] {ECO:0000313|EMBL:ETW05772.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NJM9701 {ECO:0000313|EMBL:ETW05772.1};
RG   The Broad Institute Genomics Platform;
RA   Russ C., Tyler B., van West P., Dieguez-Uribeondo J., Young S.K., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L., Chapman S.B.,
RA   Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C.,
RA   Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C., Pearson M.,
RA   Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S., Wortman J.,
RA   Nusbaum C., Birren B.;
RT   "The Genome Sequence of Aphanomyces invadans NJM9701.";
RL   Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily. Folate-
CC       biopterin transporter (TC 2.A.71) family.
CC       {ECO:0000256|ARBA:ARBA00007015}.
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DR   EMBL; KI913956; ETW05772.1; -; Genomic_DNA.
DR   RefSeq; XP_008865549.1; XM_008867327.1.
DR   AlphaFoldDB; A0A024UIT3; -.
DR   STRING; 157072.A0A024UIT3; -.
DR   EnsemblFungi; H310_03456-t26_1; H310_03456-t26_1-p1; H310_03456.
DR   EnsemblProtists; ETW05772; ETW05772; H310_03456.
DR   GeneID; 20080506; -.
DR   VEuPathDB; FungiDB:H310_03456; -.
DR   OrthoDB; 89278at2759; -.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 2.
DR   InterPro; IPR039309; BT1.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   PANTHER; PTHR31585; FOLATE-BIOPTERIN TRANSPORTER 1, CHLOROPLASTIC; 1.
DR   PANTHER; PTHR31585:SF5; RIBOSOMAL_L9 DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF03092; BT1; 1.
DR   SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        66..88
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        94..116
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        128..147
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        185..204
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        225..244
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        264..283
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        313..334
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        346..364
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        376..398
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        486..505
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        525..547
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   566 AA;  61920 MW;  F68B954BCB5673F2 CRC64;
     MKDDTAFTSM RRDDTIQSDE YGIHHIQVDT PAIADIEAAM VYAGALRPGG ALNYTSPEVL
     GLLSQYVAIG LMLGAFSNLV YPVFTVYFRM SGAQIHGITA LTVIGWNLKV LFGILSDCFP
     IFGYRRKSWM VIGWLACCAV LVCLATYDAG GPYIADTAYF RKALPTDPTL RASLVNENAK
     TRGSIVGMLC GVAVISYVVA DVAADALFVE MAQREPERIR GRLQSMIYVA RYVATVIAQA
     VIGLCLNSEE YGGTFSWSMG QQWFFVFLAV PCAIMVPISV TCVDDAPHRG VHFGQYMREF
     WQLVQNRAMW QFMVFRFSFN FLSSGLVTTA APYVQYHWAH VTTMNSQLFS IAGNLVFAGG
     LAYTGSCGTA WNWRTVIVAT NLSIVAVDAA VTFCTIYDVV RNEYVYLVVT QVIENIPSAV
     QFLVTGFIIV ELAEMGNEGI TYALLSTMNN LPIAFGPLVG NIVSGQFNVT EADVVADTRR
     DRHNVAYTYL IYYMAAILAC GVVVLCPSQK PQVYQLKVQG GNQPVVAAVV LVLSFICLMF
     SIVVSLLSMF PSTQCLVVAG GKGCHV
//