ID   A0A024UQJ3_9STRA        Unreviewed;       538 AA.
AC   A0A024UQJ3;
DT   09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT   09-JUL-2014, sequence version 1.
DT   27-MAR-2024, entry version 37.
DE   RecName: Full=Importin subunit alpha {ECO:0000256|PIRNR:PIRNR005673};
GN   ORFNames=H310_01121 {ECO:0000313|EMBL:ETW08569.1};
OS   Aphanomyces invadans.
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Saprolegniales; Saprolegniaceae;
OC   Aphanomyces.
OX   NCBI_TaxID=157072 {ECO:0000313|EMBL:ETW08569.1};
RN   [1] {ECO:0000313|EMBL:ETW08569.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NJM9701 {ECO:0000313|EMBL:ETW08569.1};
RG   The Broad Institute Genomics Platform;
RA   Russ C., Tyler B., van West P., Dieguez-Uribeondo J., Young S.K., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L., Chapman S.B.,
RA   Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C.,
RA   Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C., Pearson M.,
RA   Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S., Wortman J.,
RA   Nusbaum C., Birren B.;
RT   "The Genome Sequence of Aphanomyces invadans NJM9701.";
RL   Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the importin alpha family.
CC       {ECO:0000256|ARBA:ARBA00010394, ECO:0000256|PIRNR:PIRNR005673}.
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DR   EMBL; KI913953; ETW08569.1; -; Genomic_DNA.
DR   RefSeq; XP_008862374.1; XM_008864152.1.
DR   AlphaFoldDB; A0A024UQJ3; -.
DR   STRING; 157072.A0A024UQJ3; -.
DR   EnsemblFungi; H310_01121-t26_1; H310_01121-t26_1-p1; H310_01121.
DR   EnsemblProtists; ETW08569; ETW08569; H310_01121.
DR   GeneID; 20078171; -.
DR   VEuPathDB; FungiDB:H310_01121; -.
DR   eggNOG; KOG0166; Eukaryota.
DR   OrthoDB; 916229at2759; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR   GO; GO:0061608; F:nuclear import signal receptor activity; IEA:InterPro.
DR   GO; GO:0006606; P:protein import into nucleus; IEA:InterPro.
DR   Gene3D; 1.20.5.690; Importin-alpha, importin-beta-binding domain; 1.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR032413; Arm_3.
DR   InterPro; IPR000225; Armadillo.
DR   InterPro; IPR002652; Importin-a_IBB.
DR   InterPro; IPR036975; Importin-a_IBB_sf.
DR   InterPro; IPR024931; Importin_alpha.
DR   PANTHER; PTHR23316; IMPORTIN ALPHA; 1.
DR   PANTHER; PTHR23316:SF71; IMPORTIN SUBUNIT ALPHA; 1.
DR   Pfam; PF00514; Arm; 8.
DR   Pfam; PF16186; Arm_3; 1.
DR   Pfam; PF01749; IBB; 1.
DR   PIRSF; PIRSF005673; Importin_alpha; 1.
DR   SMART; SM00185; ARM; 8.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   PROSITE; PS50176; ARM_REPEAT; 3.
DR   PROSITE; PS51214; IBB; 1.
PE   3: Inferred from homology;
KW   Protein transport {ECO:0000256|ARBA:ARBA00022927,
KW   ECO:0000256|PIRNR:PIRNR005673};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR005673}.
FT   DOMAIN          1..54
FT                   /note="IBB"
FT                   /evidence="ECO:0000259|PROSITE:PS51214"
FT   REPEAT          124..167
FT                   /note="ARM"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT   REPEAT          167..209
FT                   /note="ARM"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT   REPEAT          293..335
FT                   /note="ARM"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT   REGION          1..71
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..44
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   538 AA;  59552 MW;  005C5B09A4DDDDA0 CRC64;
     MQRPDDRHKN FKKGIDADEN RRRREELTLN IRKTKKDEQV NRRRRMVGGS APGDFEGMVS
     DSPFPSSESA SASTSAQAYL SQLPEMVEEL NSQDIDVQLS AVTKFRKLLS IENNPPIQEV
     INLNVVPIFT AFLKAENLPK LQFEAAWALT NIASGTSDHT RIVIQNGAVP LFVYLLMSPN
     DEVREQAVWA LGNISGDSPA CRDLVLEAGA VLPLLHQLSE RASPSMLRNA TWTLSNFCRG
     KPQPRFDLVR PALSTLARLI FSQDQDVLTD ACWALSYLSD GPNEKIQAVI EAGVVPRLIE
     LLLHTNSSVQ TPALRTIGNI VTGDDLQTQF VINEGALNRL LPLLQSPKKG IRKEACWTVS
     NITAGSADQI QAVINANILP PLIQLLATGE FEVRKEAAWA ISNASSGGTR EQLHYMVQQG
     CIPPLVALLE STDSKIICVC LDALENILRM GSEEQEEQLS DENKMALIVE EYDGVNKIQQ
     LQYHEALEVY RKSLAIIETY FGGEDEEEND LLPTEDPAAQ QFTFGTGSGT MFNFQGQH
//