ID A0A024V8G1_PLAFA Unreviewed; 605 AA.
AC A0A024V8G1;
DT 09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT 09-JUL-2014, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=GRAM domain-containing protein {ECO:0000259|Pfam:PF02893};
GN ORFNames=PFFVO_01962 {ECO:0000313|EMBL:ETW19106.1};
OS Plasmodium falciparum Vietnam Oak-Knoll (FVO).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX NCBI_TaxID=1036723 {ECO:0000313|EMBL:ETW19106.1, ECO:0000313|Proteomes:UP000030690};
RN [1] {ECO:0000313|EMBL:ETW19106.1, ECO:0000313|Proteomes:UP000030690}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Vietnam Oak-Knoll (FVO) {ECO:0000313|Proteomes:UP000030690};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Neafsey D., Hoffman S., Volkman S., Rosenthal P., Walker B., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W.,
RA Alvarado L., Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J.,
RA Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A.,
RA Ireland A., Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W.,
RA Priest M., Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J.,
RA Nusbaum C., Birren B.;
RT "The Genome Annotation of Plasmodium falciparum Vietnam Oak-Knoll (FVO).";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ETW19106.1, ECO:0000313|Proteomes:UP000030690}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Vietnam Oak-Knoll (FVO) {ECO:0000313|Proteomes:UP000030690};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Neafsey D., Cheeseman I., Volkman S., Adams J., Walker B., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Plasmodium falciparum Vietnam Oak-Knoll (FVO).";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KI925073; ETW19106.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A024V8G1; -.
DR EnsemblProtists; ETW19106; ETW19106; PFFVO_01962.
DR Proteomes; UP000030690; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0043226; C:organelle; IEA:UniProt.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR004182; GRAM.
DR InterPro; IPR011993; PH-like_dom_sf.
DR PANTHER; PTHR23319:SF4; AT22714P-RELATED; 1.
DR PANTHER; PTHR23319; UNCHARACTERIZED; 1.
DR Pfam; PF02893; GRAM; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 582..599
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 80..169
FT /note="GRAM"
FT /evidence="ECO:0000259|Pfam:PF02893"
FT REGION 1..48
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 30..48
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 605 AA; 71676 MW; A866CA3652A57D9F CRC64;
MSPDFNNDTN KKRETHINNN IPNPNDGRNE DKTTILDEKR KLEESQNEEK NKCPILEIDD
HIFEINDKDH LNYIMRSSMN TFNCALSKKI LIQGKIFITM DGIYFISLFN SLFSKNTILK
IKYVDIVSVE KLTILHFLAN SIKIITKYKS FVFTSFVHRN HCYNLIMDMI YENNNTHIIP
KKGTVIIDRY HEYDTDEKND LSDEVDNTND INYHIKEGIH TNDKIYKGDI INDYKNNHII
DHYLKDNEML TDSSKIKNDF PTNIENNKTK NNITNGKCPI LHVSNYTKDN NIIYVETINK
HLPLNIDTEE NEILKNNNFI NCTNYIDSLF INRNFKDIFL DIYSNLQNQY NPLLKSVLDK
KPLNLSYEHI KDIKDLMYNK TFLTYTTEYN ILLFNNETKL IGLPDRSNVK EIFMFFFFKN
NIIIQKIITL LSNIPLAGSF NTIVTLNIHN VMNQNTNNYY TQIDFSYDIE FVKSTFFKNH
IKNNALPRLE KSIKDLKDYT KEAILQIYQN YDNQTINNNH VNPHQQNNMN QKNKSQKYQS
FTFKNNIHIA KTDLQHMTIN ELREYFKHDF KSVDHLSSYT PLMYFLIVSI TAFVIYKLLD
VKYHF
//
