ID A0A024VDX2_PLAFA Unreviewed; 540 AA.
AC A0A024VDX2;
DT 09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT 09-JUL-2014, sequence version 1.
DT 13-SEP-2023, entry version 31.
DE RecName: Full=Iron-binding zinc finger CDGSH type domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=PFFCH_05685 {ECO:0000313|EMBL:ETW26894.1};
OS Plasmodium falciparum FCH/4.
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX NCBI_TaxID=1036724 {ECO:0000313|EMBL:ETW26894.1, ECO:0000313|Proteomes:UP000030656};
RN [1] {ECO:0000313|EMBL:ETW26894.1, ECO:0000313|Proteomes:UP000030656}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FCH/4 {ECO:0000313|EMBL:ETW26894.1,
RC ECO:0000313|Proteomes:UP000030656};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Neafsey D., Hoffman S., Volkman S., Rosenthal P., Walker B., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W.,
RA Alvarado L., Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J.,
RA Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A.,
RA Ireland A., Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W.,
RA Priest M., Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J.,
RA Nusbaum C., Birren B.;
RT "The Genome Annotation of Plasmodium falciparum FCH/4.";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ETW26894.1, ECO:0000313|Proteomes:UP000030656}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FCH/4 {ECO:0000313|EMBL:ETW26894.1,
RC ECO:0000313|Proteomes:UP000030656};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Neafsey D., Cheeseman I., Volkman S., Adams J., Walker B., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Plasmodium falciparum FCH/4.";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=[2Fe-2S] cluster; Xref=ChEBI:CHEBI:190135;
CC Evidence={ECO:0000256|ARBA:ARBA00034078};
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DR EMBL; KI928153; ETW26894.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A024VDX2; -.
DR EnsemblProtists; ETW26894; ETW26894; PFFCH_05685.
DR Proteomes; UP000030656; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0043231; C:intracellular membrane-bounded organelle; IEA:InterPro.
DR GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR Gene3D; 3.30.70.330; -; 1.
DR Gene3D; 3.40.5.90; CDGSH iron-sulfur domain, mitoNEET-type; 1.
DR Gene3D; 3.30.1370.10; K Homology domain, type 1; 1.
DR InterPro; IPR018967; FeS-contain_CDGSH-typ.
DR InterPro; IPR004087; KH_dom.
DR InterPro; IPR036612; KH_dom_type_1_sf.
DR InterPro; IPR042216; MitoNEET_CISD.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR Pfam; PF09360; zf-CDGSH; 1.
DR SMART; SM00322; KH; 1.
DR SMART; SM00704; ZnF_CDGSH; 1.
DR SUPFAM; SSF54791; Eukaryotic type KH-domain (KH-domain type I); 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000030656}.
FT DOMAIN 237..316
FT /note="K Homology"
FT /evidence="ECO:0000259|SMART:SM00322"
FT DOMAIN 415..450
FT /note="Iron-binding zinc finger CDGSH type"
FT /evidence="ECO:0000259|SMART:SM00704"
FT REGION 374..400
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 540 AA; 62680 MW; 44EC937F94952465 CRC64;
MSIRNRDKNY MSHVNAGKYS MNKVSNNNSN SNISNNNYSL GLYIDNPQKA FLFDENDLKE
LFSYYKGAHD IRILADKAAA QITFNDKNMI QQVKKDINGL TINDIGTIRC IILNEGKVIE
QFLPFSANDP NVTSENDNTV SNNESTVNML KKLSSLINTN NNNNNNNNNN NINSININNI
NNVNSNNGNK KWDMNNRINN INNNNNISNN NNFNQLTNNN KNEQNDNSFA NKKLSRIELI
DIFGFPNEFD VMNKILGKNN SNINYINEQT NNMVNIELKG KPINEAPVVE RMHLSITSDN
LNAYKKAIDL IMKLLNSLFQ EFVDFCLENN FVLPENLSFK RHEYMYNSDG STKYLGFKEN
NYGEKEIYKN DFSYNKKNKN MPKSDNDKRN NNNNNSSFNM NINGAYGNNQ NLIENCPSEY
ENEKVIRICR CWQSAKFPYC DDTHKIFVEN GDNVGPYVAK LVSYKLSDEE KLKKQKYNEK
YIKLNNKMSY IKSENFNFKW FPTPIINYKF KKYVLLSFFV LTSSVLYTKK EKLYNFNTES
//
