ID A0A024VJT6_PLAFA Unreviewed; 2415 AA.
AC A0A024VJT6;
DT 09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT 09-JUL-2014, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=SCD domain-containing protein {ECO:0000259|PROSITE:PS51425};
GN ORFNames=PFFCH_03585 {ECO:0000313|EMBL:ETW28969.1};
OS Plasmodium falciparum FCH/4.
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX NCBI_TaxID=1036724 {ECO:0000313|EMBL:ETW28969.1, ECO:0000313|Proteomes:UP000030656};
RN [1] {ECO:0000313|EMBL:ETW28969.1, ECO:0000313|Proteomes:UP000030656}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FCH/4 {ECO:0000313|EMBL:ETW28969.1,
RC ECO:0000313|Proteomes:UP000030656};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Neafsey D., Hoffman S., Volkman S., Rosenthal P., Walker B., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W.,
RA Alvarado L., Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J.,
RA Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A.,
RA Ireland A., Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W.,
RA Priest M., Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J.,
RA Nusbaum C., Birren B.;
RT "The Genome Annotation of Plasmodium falciparum FCH/4.";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ETW28969.1, ECO:0000313|Proteomes:UP000030656}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FCH/4 {ECO:0000313|EMBL:ETW28969.1,
RC ECO:0000313|Proteomes:UP000030656};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Neafsey D., Cheeseman I., Volkman S., Adams J., Walker B., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Plasmodium falciparum FCH/4.";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KI928002; ETW28969.1; -; Genomic_DNA.
DR EnsemblProtists; ETW28969; ETW28969; PFFCH_03585.
DR Proteomes; UP000030656; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0030867; C:rough endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR020839; SCD.
DR InterPro; IPR013721; STAG.
DR PANTHER; PTHR22929; RNA POLYMERASE III TRANSCRIPTION INITIATION FACTOR B; 1.
DR PANTHER; PTHR22929:SF0; TRANSCRIPTION FACTOR TFIIIB COMPONENT B'' HOMOLOG; 1.
DR Pfam; PF08514; STAG; 1.
DR PROSITE; PS51425; SCD; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000030656}.
FT DOMAIN 614..703
FT /note="SCD"
FT /evidence="ECO:0000259|PROSITE:PS51425"
FT REGION 25..139
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 212..250
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 743..776
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 957..976
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1629..1691
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2126..2205
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2264..2309
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2378..2402
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 25..59
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 60..79
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 114..132
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 745..761
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1629..1643
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1644..1664
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1665..1691
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2131..2148
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2159..2173
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2175..2191
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2271..2308
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2415 AA; 285743 MW; E1ED61C41F18F485 CRC64;
MDNNKMFLRR SSRLSHNFDE NNRNRELIEK REGGNMVKKQ ITHERRKSIY KDKDESLLST
DENSSTYDSD YTVSVNDDDS SVGNKRKYNK ENENNKNNNN NNNNRHNRRN KNKHNNNNNN
SSGDNSNAIT PFYDGDKNKD NECIENVRTR KNNNYEKNNL KNNSYIDILN EDIDDEDFDI
FKRSKMDRSK RISTSYKNTQ YNDINLRKRK SVYVESSNSE DSNKSDDDDE EYINEESSRN
NKKKKLKQTY SSSTFKNKKN FVNKKVYKNF EDFNLYENIK KNPKNLHDII EEIYYSLFNK
DTNEKVKIST FFLNFLAECS GNETLTWTVD IIDYIDKQIY LYEDIPNNNQ LQNVIIGNTI
NNTTLSDIMT PSTVRSSNKI TNMDEIIRDE NNFEKVCTFK CEKLEQYLST DLNTDVLIKI
KNENNKSYKA FANFFADFSF HFDENYIYDI LYICIWIFSL SVSKYRKIRF TSSLASLSIL
LGLCKKIRYI NNHERQSRKQ LMAEYTRERK NINNLTGAGR KRNSSTTITR TSNTIHNNNN
NKNNSNNSTL DIINDDRSLN IEDLINYKNK KDTELYNIVE RNLIISQLID NINEDRKNLT
ILNNFLLCTY NILYKNKIKD IFIDIRIITL EYFYLYLDVL TLYFTNRKFT KLLIWILYDK
DNKIKICCLK ILIYLCNYYN NSNKKIFKIV ELLYMSKKKL LNLIFDSDYN VRIKTFELIL
EMNKMKLNRT EFLHFKKTLK NKKNSAHNKK DDPHINDNTS SSEYEEDTDV NSTESEKIQN
KKSIVLYNHN KRNKKNIGNK QNHDGKEDDI YVISDNMCIL STKEKKIVSN LIWFNNNNKI
SQMITSLIYE SQIKNKIKNY EKRKHNYFDV EHNDTNSEIV KYNIIYLTKY LNKNIPTVKN
FVHYFDYMKN YNENLKLYTV IDKFISGIRE KLDCINNIDI IIELLCEDDI SLSYIGKKKG
SDKTNDKEKD MGEDENNVQL SQRFNNNDNN VIDGERVIDG EHVIDGERVI DGEHVIDGER
GIDGEHGIDG ERVTENNTET RKHSTYLSHD CDKNNSDKGR DLRKCLLYIC ESSYRNLQND
INEMEKNKNR KGTSASTNSN NINNINNNVN INGVLLSDKN TAHSKLNNDT NKIKKMIIYT
FYIIKNSKQL IKLHQTNQEH LLLVFKILKI ALYECKHIYK HEEKNNIYNF SSTIMEYFKN
DIESNMNYFF NNIYIYLKET YEYLFYLLKN YKLPYYSSKY TMNIISIFLS LNDSLKGSNK
LSSDLFFDLY YTYFNNFLEN FLYYQKNYNM EVDRNEEDNK GEDESDTHDE HGEDNVYLLN
KKRKIILISE NLVNKDKNII EAIEEEIILN LTNLIHIYTL GFNYINNDLS NYKDIKNDIL
KKKKNIEKSI KMLCEQDYFS IKVKEKCQSF FFKDNIINLN EFLEENLLTS YYDENDIESY
THENNIQSDQ YSEDVEMSYD DNDEDINYIG KKKNKNNKQK DKNKHNNINN INKRKTMNIQ
DILHLNDNMT KNNKNSSYIQ SEEENFQYEQ NLHNLYYSSD ACIHANVIIH LCLHIIKAKV
NSIYYYDEDV VLHTPSSRLL LLCIDQIYII YENYIYHLCK KRYFFNFLYN IFLHKYKNDK
IDGKKNEWEK KNEGEKKNRN NQHNLNDNES NLENNIQNNN IKIEINENDK SEKNNNIDDN
KNKNNKENDS NNINLEDLKK LHNLNNKKID ALKNIFIELN YIYANISTLR KDINHVLIFL
IRSCNNTILR YGTFLNLMNI AQLENILLYS IEDLNKYKTL ELFLNKIKNN DEIGSCMDIH
IKEDMENYLD KDEEINKYKN VSRYIYKDDN ILFNFVTELF KYVENMNNNN YNFVNSFLSI
DISVFFPINT YTYIADMCKI YNKDVLSKNE KILEMQYMHM TLIIAQFILN CNNINIFNSC
LGVLLLIHLN VKNKGLSSIA LNFHNKLKKY NIDVFYEVLL CALIGLYTAY INNALEEKDL
LLFSASIASR LGVKIVEKQK LPLCKFIHSC VNCALNLKNQ NSFLKYILPY AQKLSLSEYQ
LNYLKKQILN LIDSYNVANQ SHIKYENSIF EHMMLIICKK RKLNDEFKDI NYENSYMNLN
ESIHMNISKN IINRNRQSEA STIIKTRKSV LQMNRNKDKD QVDKMNDDEN KDEDNDGNNN
NDSYNNDIQN DDLSDENNNI DKKKSSNDED NINSESDINE NNYVNQNMRH YRIKKELIHH
ENEHAEKEQT NNIHKAKDKY KRINKQNYGN EKNNSNNNEI YSELDEKSHS NSTLSDLVSL
NDEDNNNNNN DKGKSHYDMN SSPKPVRSKK YNNMHVIPKY NSELNMNDTD NKSMDINSKH
SVDISLNSSL GNISYKDDDN MSLISDVKGK NKYFTQNADD SNSDIVPGMS PIKKNDGKRS
ELSTPISYAD DLMNF
//
