ID A0A024VMF4_PLAFA Unreviewed; 1130 AA.
AC A0A024VMF4;
DT 09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT 09-JUL-2014, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=Tr-type G domain-containing protein {ECO:0000259|PROSITE:PS51722};
GN ORFNames=PFFCH_02662 {ECO:0000313|EMBL:ETW29889.1};
OS Plasmodium falciparum FCH/4.
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX NCBI_TaxID=1036724 {ECO:0000313|EMBL:ETW29889.1, ECO:0000313|Proteomes:UP000030656};
RN [1] {ECO:0000313|EMBL:ETW29889.1, ECO:0000313|Proteomes:UP000030656}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FCH/4 {ECO:0000313|EMBL:ETW29889.1,
RC ECO:0000313|Proteomes:UP000030656};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Neafsey D., Hoffman S., Volkman S., Rosenthal P., Walker B., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W.,
RA Alvarado L., Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J.,
RA Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A.,
RA Ireland A., Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W.,
RA Priest M., Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J.,
RA Nusbaum C., Birren B.;
RT "The Genome Annotation of Plasmodium falciparum FCH/4.";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ETW29889.1, ECO:0000313|Proteomes:UP000030656}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FCH/4 {ECO:0000313|EMBL:ETW29889.1,
RC ECO:0000313|Proteomes:UP000030656};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Neafsey D., Cheeseman I., Volkman S., Adams J., Walker B., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Plasmodium falciparum FCH/4.";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KI927945; ETW29889.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A024VMF4; -.
DR EnsemblProtists; ETW29889; ETW29889; PFFCH_02662.
DR Proteomes; UP000030656; Unassembled WGS sequence.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0006412; P:translation; IEA:UniProtKB-KW.
DR CDD; cd01514; Elongation_Factor_C; 1.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.30.70.240; -; 1.
DR Gene3D; 3.30.70.870; Elongation Factor G (Translational Gtpase), domain 3; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR InterPro; IPR041095; EFG_II.
DR InterPro; IPR035647; EFG_III/V.
DR InterPro; IPR000640; EFG_V-like.
DR InterPro; IPR031157; G_TR_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR43261:SF1; RIBOSOME-RELEASING FACTOR 2, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43261; TRANSLATION ELONGATION FACTOR G-RELATED; 1.
DR Pfam; PF00679; EFG_C; 1.
DR Pfam; PF14492; EFG_III; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SUPFAM; SSF54980; EF-G C-terminal domain-like; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS00301; G_TR_1; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000030656}.
FT DOMAIN 22..341
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
FT REGION 540..559
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 910..938
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 921..938
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1130 AA; 132754 MW; 96520CFC8D560FA8 CRC64;
MFKRVYVYKN SFWKYKKRFF SKKLVNIGIL AHIDAGKTTI SEDILYQSKE IKVKGNINDQ
NTQLDFLKQE RERGITIKSA YSCFEWNKIK VNLIDTPGHI DFSNETFISL CVLDKCIIVI
DSKEGVQIQT INIFRYIKEN LPIYFFLNKM DINHIDIDSN FLSIKNRLTK KGLLITYPIY
ENKKLKYILD IPSMVLYSYP HINYGQTFMY NSYFLKTLLE GSLYEKKLYS HFAMINPKPD
NLSKENKNKN NINIANVLND DIIDYIIKKR EEIIEILCDL DNTIEYKYLN NIPISYEHFK
NSLSLCIDKK YIFPIFSGSA LHSYGVHILL DYITHNEKGM EKGMEKGMEK GKKGMEKGME
KGMEMEKERQ MNHNKQRTNN NTNETPFLSY ERINKDKYHI YQNKKCGNNS DMYHPYDITY
NHNNLIKNTD VIKNNIIFNN KKALNSLYKT IIFIFKLSNE KNGFNTFCKV FKGKLSKNTK
LLNLRNKKTE IVKGIYKVKA DRYITTNVLD TNDIGMVRGF ENIILCDIIC EKDDEKPSHN
NNDFFSEDQT TDHNKQNNEY SHSNHIENTL NELYHKSHKE DEKNHALHEG TYSQNNLFIG
HNDLPPLSNI YKLLKDEIPN KQWLYFLKSY KKRISKNIIV CTCAIEPKEY KKEKDLKNIL
KQICLEDNSI LIFTDKNNKL VIGSIGILNI EVIIDKIKND YNIDIKTSPV EIIQKEYIQG
YYENSIKKEM KVGSYISTII LGFVIKEKDE FIDISSYVQN VLKHEKISHF LSSEEGIKNN
ISNNKYNNNN KYNNNNKYNN NNKLNISDNL DKDNNLLLYD DIRFEDNKKM YISTTNDDRQ
NYDEHHNINI LDNMEIKEST EKDRKKNYVY NNLKLGNSKS MYDTKGVKNW VHKYNDDHDK
IYLEDNIKDH PHKQSIDDEP ELLCDNDDND DNDNDDDNDD VDEYLLNFNY DTLFENSVTV
HKDVLLYIDE LKKMNKKKKN VYDNILNSCI ISLKNCLSNG YHTNGNIINT EIIIKNLKIF
DSSTTAVAKY ACNHLYYEMI KKANIQIVNP LSLILIQTDE AYTGIIVKDL IQYRNGTIIQ
IMKNKESDFK LMKIYAIIPV KFTHNYSSIL RSISSGHANF LMTFCGYKKC
//
