ID A0A024VW41_PLAFA Unreviewed; 1777 AA.
AC A0A024VW41;
DT 09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT 09-JUL-2014, sequence version 1.
DT 13-SEP-2023, entry version 36.
DE RecName: Full=Shikimate kinase {ECO:0008006|Google:ProtNLM};
GN ORFNames=PFFCH_00064 {ECO:0000313|EMBL:ETW32543.1};
OS Plasmodium falciparum FCH/4.
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX NCBI_TaxID=1036724 {ECO:0000313|EMBL:ETW32543.1, ECO:0000313|Proteomes:UP000030656};
RN [1] {ECO:0000313|EMBL:ETW32543.1, ECO:0000313|Proteomes:UP000030656}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FCH/4 {ECO:0000313|EMBL:ETW32543.1,
RC ECO:0000313|Proteomes:UP000030656};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Neafsey D., Hoffman S., Volkman S., Rosenthal P., Walker B., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W.,
RA Alvarado L., Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J.,
RA Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A.,
RA Ireland A., Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W.,
RA Priest M., Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J.,
RA Nusbaum C., Birren B.;
RT "The Genome Annotation of Plasmodium falciparum FCH/4.";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ETW32543.1, ECO:0000313|Proteomes:UP000030656}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FCH/4 {ECO:0000313|EMBL:ETW32543.1,
RC ECO:0000313|Proteomes:UP000030656};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Neafsey D., Cheeseman I., Volkman S., Adams J., Walker B., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Plasmodium falciparum FCH/4.";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KI927792; ETW32543.1; -; Genomic_DNA.
DR EnsemblProtists; ETW32543; ETW32543; PFFCH_00064.
DR Proteomes; UP000030656; Unassembled WGS sequence.
DR GO; GO:0016765; F:transferase activity, transferring alkyl or aryl (other than methyl) groups; IEA:InterPro.
DR Gene3D; 3.65.10.10; Enolpyruvate transferase domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR036968; Enolpyruvate_Tfrase_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR013792; RNA3'P_cycl/enolpyr_Trfase_a/b.
DR InterPro; IPR031322; Shikimate/glucono_kinase.
DR Pfam; PF01202; SKI; 1.
DR SUPFAM; SSF55205; EPT/RTPC-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000030656}.
FT REGION 1..36
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 109..192
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 802..843
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1021..1040
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1196..1240
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1441..1461
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 109..147
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 168..182
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1203..1232
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1777 AA; 211951 MW; D13D830E958237FA CRC64;
MILNQNIHLN EENKNDITTK NNNNNNNNNN NNNNKVNNQI CVQHKLPCDY TFYQNIKKED
YKQCGLFNTT SKAFIDMTLY VMRTWGIHIK VNHKGIYYVQ KKEMYQLYDD NNNNNNNNNN
KSDICLNRVN PNKCSSEKKT NNPNSSSILK KDKEKKKNQM DGKIVTNLVK GDNKEEEGNN
NIIKNDDSAS KGTNEHMMQR INDAETTQNN TLHKENKLCT TKDQNKIHTK INSKENEKVK
KYYYYHINND LGLYFYFLVG FIIKKKNCTI SLKLNINNLN VKYKGNNIYK IKTVMYQKDI
YNYYLLNILL LVGVKIYIRQ HNKLNKESEY NVNSQNLIGS KSKSSKIYMV HFITSEISFN
KKKILRPFYK IQKKINNKYK RIIMNQSAHI NIKESKNNII SNNVEEKNSV TSNIVSNISS
NNISPYYKSI KENNKMKKTN NCIEHILNNY KIKYNIYEKI YIKYETNNNH MLSFKIVIDA
ESFSDDFFSI CILFSHFILS NINENIIFKI KNIHNQNIKE STRIYHVVFI LKLFFHNLLF
ISCTNNSIYI TKMLHPLQNI QFYRYKKNIR TNNQKIYNTN YIHNKYEKIQ NFVNNSKYVI
NDMQSLYLYV DTQNDHRIIF MSTILSLIFK NIIIPKCDNV HKSFPLFFHY AKKYLHIYVQ
NGSNQFINTY NFQDVNNINL LHCTKKKRPQ RGSTPDEKYK GGEIKGNDII KESDIIKCND
IIKESDVVNK NEIVENMNII IEKDEIKTDK YTEPIKYDNT SDAKSISTST SVLSSESSNE
LSDCCMNKLT KENMEMNNVI ITKNNNNDNN NENNENNENN DNNENNENND NNNNNNNNNN
VEVYKPNYKI NGLQNIINSC LNFICSKRKN IKNKIKNKII KHKKNKIINH KKKKKNCNTR
HRGNTQINNK LVLINITPYI LRYPNNNKSS KKLSCTKEIK KKTFPRICES YDIKKNIDIH
NVNKKNYKKI DDTLNVHKEE IDTSKQHTDE KICKKIQKYL YLDVKRKRYI SLYMYNKKKG
KDTNNKNIQK KKKKEEEKKQ ISYNISSKHN SILNNRMKYN NIIDMYKRNN FIYKDDNYKR
IYTYDEILEN DINISYLIKQ INILNVTIIC GMRNVGKTFL SKKIENNIII DIDEYILKDE
IKFDKLSISD FRYYEYVTFI SSLYLAFYIL TFDRNLSAPK DQTGATIKHV DIRDEKINSK
NQNKQTEYDN DINDNNNYNN SDNHNLLHNN KDNQHTSTKK KIQKKVSFSD VCEIYVDGPN
FENKNYDDNI FYTYTNKGIT FYNKKINDLF CKLRKKCIQE KQNGEHQMTN VTIVLGGGII
EFDKSKEVLK KLKNTILIKR DIDEIYDICI NDNIKPKLNG NIKDIIHRRT ILYDKLSNAF
HFIIPSENMI NKYIRHSEYN KYINRNELIV HSFLRFFNYP FFKKPLIGDI ITNYKIDKNE
KNDEKNDEKK KKKKKKKNDC NHNHINNYYR VLYINLNNLR HFPYMNLLKE DYDIIHIKIY
KYEQIKLLEL AIFLIRSCTC KEYKIIVKLY PQYFFTYQEY IIKKKKHKKK SLKNKKKSNK
KYEFDNYICE NILHIFYKYK INIFELDNHF LKVAKKILSY KKENIFFIIS KKEKIINKLK
IQSDLYKLNI WQADIIKLSS SNQISLTECN LLENILYDFY VDTINQPANT LLFEKRLHNN
DKNEQTHILY YNATDKCLFS FLYNNITHLS YNKRFLPIIK KNKMYGYLSN IKEDHTNQNI
QSESYYTQSS YYNRVKPILF YTIIQNVKEK NDHQQTN
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