ID A0A024VYZ1_PLAFA Unreviewed; 1460 AA.
AC A0A024VYZ1;
DT 09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT 09-JUL-2014, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=Potassium channel domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=PFTANZ_05639 {ECO:0000313|EMBL:ETW33672.1};
OS Plasmodium falciparum Tanzania (2000708).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX NCBI_TaxID=1036725 {ECO:0000313|EMBL:ETW33672.1, ECO:0000313|Proteomes:UP000030708};
RN [1] {ECO:0000313|EMBL:ETW33672.1, ECO:0000313|Proteomes:UP000030708}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tanzania (2000708) {ECO:0000313|Proteomes:UP000030708};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Neafsey D., Hoffman S., Volkman S., Rosenthal P., Walker B., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W.,
RA Alvarado L., Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J.,
RA Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A.,
RA Ireland A., Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W.,
RA Priest M., Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J.,
RA Nusbaum C., Birren B.;
RT "The Genome Annotation of Plasmodium falciparum Tanzania (2000708).";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ETW33672.1, ECO:0000313|Proteomes:UP000030708}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tanzania (2000708) {ECO:0000313|Proteomes:UP000030708};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Neafsey D., Cheeseman I., Volkman S., Adams J., Walker B., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Plasmodium falciparum Tanzania (2000708).";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; KI926563; ETW33672.1; -; Genomic_DNA.
DR EnsemblProtists; ETW33672; ETW33672; PFTANZ_05639.
DR eggNOG; KOG1420; Eukaryota.
DR Proteomes; UP000030708; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 1.
DR InterPro; IPR003929; K_chnl_BK_asu.
DR InterPro; IPR013099; K_chnl_dom.
DR InterPro; IPR047871; K_chnl_Slo-like.
DR PANTHER; PTHR10027; CALCIUM-ACTIVATED POTASSIUM CHANNEL ALPHA CHAIN; 1.
DR PANTHER; PTHR10027:SF10; SLOWPOKE 2, ISOFORM D; 1.
DR Pfam; PF03493; BK_channel_a; 1.
DR Pfam; PF07885; Ion_trans_2; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE 4: Predicted;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Potassium {ECO:0000256|ARBA:ARBA00022958};
KW Potassium channel {ECO:0000256|ARBA:ARBA00022826};
KW Potassium transport {ECO:0000256|ARBA:ARBA00022538};
KW Reference proteome {ECO:0000313|Proteomes:UP000030708};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 12..32
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 44..70
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 182..205
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 217..238
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 277..302
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 322..340
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 347..364
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 285..371
FT /note="Potassium channel"
FT /evidence="ECO:0000259|Pfam:PF07885"
FT DOMAIN 523..618
FT /note="Calcium-activated potassium channel BK alpha
FT subunit"
FT /evidence="ECO:0000259|Pfam:PF03493"
FT REGION 771..792
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1460 AA; 174107 MW; 6A1205DAE82B2163 CRC64;
MKSGLFSMND IFFLVNSIFK YFLILLNGSH LLKLLYSSKE NIHIIEGLLC IITGVILKLS
LIYIYCTYFM NIYIIKDYRR KNVLNIFNMN NNYKRNGNVI ESDDFEYRKL IKKFFFKKVY
YSIKKKHKRI ELYMLKIYNS NFNYYFCNIR DMCYTIIWYI SLYYWRRDTY NMIWGFNKIP
TYIYNMLLIL LSTSYIDLVM VIISYNKSKY YLMKSKLLID IFFSAPCTYL FSKFIFVFEH
QIDIYFMMGF LRNIKIFLNV SYVRIEHNSI LTNTEIKIIR IVLGVLLLCN AFASTIYTIQ
AIHPYNLDNE NFNYFLNSYL DYFYFSIISI STVGYGDIFP INKLSKVVCI IFIFWTFIWV
PIQFNDLIIS IFSKKKTYGK ISMNNQKFIL LIGDVEPQQL NVFLFESVAQ GNKLKFHLLT
TYPINIYDEQ IKIADHFCIS LYIKNFDLNE KENINLLYSI NAQNAYYLFL FSNKFHNGHY
NIDTKSFTRL LILKKFLHGK KNAVIELRSN CVSNIVRSIG CENFIIVNLK HSLIVKNIKY
PGFITLILNL FTAYNYDISS YNFNDIASYP SLKYIGEFNR GSRTKIFSFI VHKNMVGLIF
DKLFYKLYES LGIILVGIET NTTNYYINNK KHKNKNSYVD DNFTTMRKNN MKNKKKKSFK
FIYLHLLKKY GHTNHYTQKK KKKKYDNIIN HHGSKSKMEY STQLRHNNKT IKIYDEYNTI
ETYQNYLNYE TINNSRINIY NSDEKKKKYN DVSPTNNILT NYKNGKLHIE KRDDFDNNNN
NNNNIVKSRK KGRENKNDEI INVCININSD IKKKYNNNNN NNNNNDNDNN NIINDHDNYN
IYNNLNSNLK CRCLPNTKKN KAQNVNNVTN NKDNDVSVKR IKTHLQDDNT IDNKKELKCY
LNLLGKNYAI RDSDKCVVIA NSRKVIKYLS KAKSLFWIFE IKSKKKDNIS YDLKSVIKTK
QTFNKYFTTN IKKKLPTTSI QNNVYVNKNA HIIAMNYHDL FNTYRISRIF TKNNYNYKRK
NSRKKHLFRN LNGEFNETKL YHHCNNTHNI KTTDKKNMEK LDKLYFSTKL NSKSNTNIHI
HNNNNNNNNN NEHYDDEIKT YYFNLTEKNS HLLLNYKKQL KKKNYINTCY SVNKSDESIN
KIKNMNSDNN NINSNNINSN INNNNNNNTK LNHTLKNRIT FSYMEACEKY FPTENRNNKL
LLIINCTCNI IQLIKMFNNK YKYNVIILTD EIPTMNIMDL FKYNVVFIKC KILDDYNLIN
SGLMNAEYIL ILPTEAKNIN EINEIDMNTI IVTRKITHLL KKKKRTYYIN NIITELINPS
NVIFLEENKM IKLKDKKSSY DDFFPYVNSS QFYSSNIICE TMLYNFMTHH KSFTDFSVCT
NTLECLIKFL RIIYICDLSK YYDFSFKKIK TFRDLFYFLS KKNIITIGLY RKGDKKVPFY
IYTKPNENCL LRFDDIVYIL
//
