ID A0A024WN20_PLAFA Unreviewed; 1387 AA.
AC A0A024WN20;
DT 09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT 09-JUL-2014, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Diphosphate-fructose-6-phosphate 1-phosphotransferase {ECO:0000313|EMBL:ETW48629.1};
GN ORFNames=PFMALIP_03344 {ECO:0000313|EMBL:ETW48629.1};
OS Plasmodium falciparum MaliPS096_E11.
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX NCBI_TaxID=1036727 {ECO:0000313|EMBL:ETW48629.1, ECO:0000313|Proteomes:UP000030699};
RN [1] {ECO:0000313|EMBL:ETW48629.1, ECO:0000313|Proteomes:UP000030699}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MaliPS096_E11 {ECO:0000313|EMBL:ETW48629.1,
RC ECO:0000313|Proteomes:UP000030699};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Neafsey D., Hoffman S., Volkman S., Rosenthal P., Walker B., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W.,
RA Alvarado L., Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J.,
RA Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A.,
RA Ireland A., Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W.,
RA Priest M., Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J.,
RA Nusbaum C., Birren B.;
RT "The Genome Annotation of Plasmodium falciparum MaliPS096_E11.";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ETW48629.1, ECO:0000313|Proteomes:UP000030699}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MaliPS096_E11 {ECO:0000313|EMBL:ETW48629.1,
RC ECO:0000313|Proteomes:UP000030699};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Neafsey D., Cheeseman I., Volkman S., Adams J., Walker B., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Plasmodium falciparum MaliPS096_E11.";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KI925568; ETW48629.1; -; Genomic_DNA.
DR EnsemblProtists; ETW48629; ETW48629; PFMALIP_03344.
DR UniPathway; UPA00109; UER00182.
DR Proteomes; UP000030699; Unassembled WGS sequence.
DR GO; GO:0003872; F:6-phosphofructokinase activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.450; -; 4.
DR Gene3D; 3.40.50.460; Phosphofructokinase domain; 1.
DR InterPro; IPR000023; Phosphofructokinase_dom.
DR InterPro; IPR035966; PKF_sf.
DR PANTHER; PTHR43650; PYROPHOSPHATE--FRUCTOSE 6-PHOSPHATE 1-PHOSPHOTRANSFERASE; 1.
DR PANTHER; PTHR43650:SF1; PYROPHOSPHATE--FRUCTOSE 6-PHOSPHATE 1-PHOSPHOTRANSFERASE SUBUNIT BETA 1; 1.
DR Pfam; PF00365; PFK; 2.
DR SUPFAM; SSF53784; Phosphofructokinase; 2.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000030699};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:ETW48629.1}.
FT DOMAIN 133..458
FT /note="Phosphofructokinase"
FT /evidence="ECO:0000259|Pfam:PF00365"
FT DOMAIN 923..1190
FT /note="Phosphofructokinase"
FT /evidence="ECO:0000259|Pfam:PF00365"
FT REGION 611..705
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 611..668
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 669..683
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1387 AA; 162230 MW; 64B77552574918F4 CRC64;
MDIENSKKHL SELQEERRRH KITLPDMFKR KVLIKEENND TYEKNLETKN DMCYSLNRSD
DEKEYLKMKF PNIINNPIIK LYTDPYYTIH MSDKKMNTTD SINTSMDMSS YNYTTNSFMK
EMINMYKPHE KLNIGILFTG QQTPGGHNII CGVFDCLKKK NKKNTLYGFM NGFQGMLKYN
FMELKNEYIS MFRNSGGFDM IKSSDIQIIN EDQKKKCFKI CRQLNLNGLV IIGDVSGNKS
TAILSEYFET ITIYSNNNIP YDNIQSYNMS YDNISTYDFT YDNISDISDE EINKKYPKKN
KSFVKTSIVS APTCVYNEMK NKYIECSLGF DTTIFSYCQY ISYLITHIQT YLQGYHFIKV
MGNSSSHIAL ECFLQTKVNI ILVTEEIKKN NLTLDQIIQF IVDVIQNRYK KYHKNYGIVI
IPDGILKKIT QFKKLVTSII HIKTKFIENK INILTDLQNI LSKHLIKEQQ EFFKTLPDFF
QIQLLEEICS QQFHYARLST ELLLTHLVKK KLEERQINDL EFHTHSYGKE VTCSLPTNFD
CAYSYILGFS CVEMLQHKYN GYMCVIKKLK NLLLNVNDIE ILGIPLCHIM KIKKKNKNVA
QINIVEQVKS AGEKKKKIEE KDNPQEIKEN GKINKAEKPT KKNKTEKKDK VTKKDKTSKK
DKNNTTDRVK KSSSNIQNDN VNKKDDALTN DLCEPTDSTT NNQNKNALVI RNDPFEEFFI
KRTKVNLKDD AYFIKYKKYR YMYLYEDHYR VLTGIQYEHN FCIDYDDKSL KFRNKLNSTL
SSNDYITIKP NNIFSKINFT ISGLTKEYFN KKEHNEEKSS MTQNNILQNG VILQNNNTYK
FNYCKHSSML SEIEKMLTAS AIKFNTILIR HNTRITYINN NFFNKLYTIS FIHIPKIKDF
YILQDNQFHL KQNYRNVTCP KNVGVVLLSH CTPGTNNILV GLHQRLSINN FKLIGFIKGL
KGLLNNDICL INDNNLKTSI NIGGFPLLGV HIQYEKKTND DQILHIHDLI KENNISKIIK
SCKNNNITNL VFIGDEKVIT LMNILNDIFI NKDVNIKIVS IPISLYNSFD KNLIECSIGY
HSMVRHISDI ISNVQSNCLN INTYYYFIKI HTNISSSLIL SVQLQTHCNI CYIGESLNNQ
LTSLHTVIEN ISLIIIERIN RMKYYGVILF SSNLIYYIND FHELCKDVDE NIKNVQEIDE
IVKNDILPER FQKILKKESV DLLNLLTESM KDKLLRKEKR ENEDIDSNFE VMLINEIKKY
IQNLMEKSKQ NKELYCYKKH MNTISSPINV KNIKVYSDID YILHFQTLIK VIDREINCFF
PTHFDNSLAF SHGLLAGIAV ENDLLNYVTS IKHLNLNKQN WSSSLYPGIY FINNKDDKGH
FNEVLKK
//
