ID A0A026WW58_OOCBI Unreviewed; 313 AA.
AC A0A026WW58;
DT 09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT 09-JUL-2014, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=Alcohol dehydrogenase [NADP+] A {ECO:0000313|EMBL:EZA59354.1};
GN ORFNames=X777_16000 {ECO:0000313|EMBL:EZA59354.1};
OS Ooceraea biroi (Clonal raider ant) (Cerapachys biroi).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Dorylinae; Ooceraea.
OX NCBI_TaxID=2015173 {ECO:0000313|EMBL:EZA59354.1, ECO:0000313|Proteomes:UP000053097};
RN [1] {ECO:0000313|EMBL:EZA59354.1, ECO:0000313|Proteomes:UP000053097}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24508170; DOI=10.1016/j.cub.2014.01.018;
RA Oxley P.R., Ji L., Fetter-Pruneda I., McKenzie S.K., Li C., Hu H.,
RA Zhang G., Kronauer D.J.;
RT "The genome of the clonal raider ant Cerapachys biroi.";
RL Curr. Biol. 24:451-458(2014).
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DR EMBL; KK107109; EZA59354.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A026WW58; -.
DR STRING; 2015173.A0A026WW58; -.
DR EnsemblMetazoa; XM_011332809.2; XP_011331111.1; LOC105275736.
DR EnsemblMetazoa; XM_011332810.2; XP_011331112.1; LOC105275736.
DR EnsemblMetazoa; XM_011332811.2; XP_011331113.1; LOC105275736.
DR OMA; RLIKMEH; -.
DR OrthoDB; 890110at2759; -.
DR Proteomes; UP000053097; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR Gene3D; 3.20.20.100; NADP-dependent oxidoreductase domain; 1.
DR InterPro; IPR020471; AKR.
DR InterPro; IPR018170; Aldo/ket_reductase_CS.
DR InterPro; IPR023210; NADP_OxRdtase_dom.
DR InterPro; IPR036812; NADP_OxRdtase_dom_sf.
DR PANTHER; PTHR11732; ALDO/KETO REDUCTASE; 1.
DR PANTHER; PTHR11732:SF507; ALDO_KET_RED DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00248; Aldo_ket_red; 1.
DR PIRSF; PIRSF000097; AKR; 1.
DR PRINTS; PR00069; ALDKETRDTASE.
DR SUPFAM; SSF51430; NAD(P)-linked oxidoreductase; 1.
DR PROSITE; PS00798; ALDOKETO_REDUCTASE_1; 1.
DR PROSITE; PS00062; ALDOKETO_REDUCTASE_2; 1.
DR PROSITE; PS00063; ALDOKETO_REDUCTASE_3; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000053097}.
FT DOMAIN 19..289
FT /note="NADP-dependent oxidoreductase"
FT /evidence="ECO:0000259|Pfam:PF00248"
FT ACT_SITE 51
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000097-1"
FT BINDING 113
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000097-2"
FT SITE 80
FT /note="Lowers pKa of active site Tyr"
FT /evidence="ECO:0000256|PIRSR:PIRSR000097-3"
SQ SEQUENCE 313 AA; 35178 MW; 559DD71410A27ABD CRC64;
MAAIPTVTFS NGHKMPMLGL GTFKSNKGEV GEAVKEAIGL GYRHIDTAFF YDNEKEIGEA
IREKIKDGTV TREDLFITTK LWNTFHKEHL VVPACKQSLV NLGLDYLDLY LLHWPFAFKE
GDVMLPTDAN GKLIDSDVDY VETWRGMEEC IRQGLTRSIG ISNFNSEQIT RLLESAKIAP
VNNQFEVNIN MNQEKMIDLC KKRNMTVTGY CPLGQPGNPL GIGNRLDSPV ILQIAKKYSK
TPAQVALRYV FQHGVTPIPK SVTKSRIKEN MEIFDFALTA DEINAIRKLG TGERIAIFNA
AKHCKNYPFS IPF
//
