ID A0A031LX18_9GAMM Unreviewed; 505 AA.
AC A0A031LX18;
DT 09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT 09-JUL-2014, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE SubName: Full=Acetyl-CoA hydrolase {ECO:0000313|EMBL:EZQ12320.1};
GN ORFNames=CL42_01010 {ECO:0000313|EMBL:EZQ12320.1};
OS Acinetobacter sp. Ver3.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Moraxellales; Moraxellaceae;
OC Acinetobacter.
OX NCBI_TaxID=466088 {ECO:0000313|EMBL:EZQ12320.1, ECO:0000313|Proteomes:UP000023816};
RN [1] {ECO:0000313|EMBL:EZQ12320.1, ECO:0000313|Proteomes:UP000023816}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ver3 {ECO:0000313|EMBL:EZQ12320.1,
RC ECO:0000313|Proteomes:UP000023816};
RA Kurth D.G., Ordonez O.F., Albarracin V.H., Revale S., Farias M.E.;
RT "Polyextremophylic features in the genome of Acinetobacter sp. Ver3
RT isolated from a high altitude andean lake.";
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the acetyl-CoA hydrolase/transferase family.
CC {ECO:0000256|ARBA:ARBA00009632}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EZQ12320.1}.
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DR EMBL; JFYL01000002; EZQ12320.1; -; Genomic_DNA.
DR RefSeq; WP_035263930.1; NZ_JFYL01000002.1.
DR AlphaFoldDB; A0A031LX18; -.
DR eggNOG; COG0427; Bacteria.
DR Proteomes; UP000023816; Unassembled WGS sequence.
DR GO; GO:0008775; F:acetate CoA-transferase activity; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0006083; P:acetate metabolic process; IEA:InterPro.
DR GO; GO:0006084; P:acetyl-CoA metabolic process; IEA:InterPro.
DR Gene3D; 3.30.750.70; 4-hydroxybutyrate coenzyme like domains; 1.
DR Gene3D; 3.40.1080.20; Acetyl-CoA hydrolase/transferase C-terminal domain; 1.
DR Gene3D; 3.40.1080.10; Glutaconate Coenzyme A-transferase; 1.
DR InterPro; IPR026888; AcetylCoA_hyd_C.
DR InterPro; IPR038460; AcetylCoA_hyd_C_sf.
DR InterPro; IPR046433; ActCoA_hydro.
DR InterPro; IPR003702; ActCoA_hydro_N.
DR InterPro; IPR037171; NagB/RpiA_transferase-like.
DR InterPro; IPR017821; Succinate_CoA_transferase.
DR NCBIfam; TIGR03458; YgfH_subfam; 1.
DR PANTHER; PTHR43609; ACETYL-COA HYDROLASE; 1.
DR PANTHER; PTHR43609:SF1; ACETYL-COA HYDROLASE; 1.
DR Pfam; PF13336; AcetylCoA_hyd_C; 1.
DR Pfam; PF02550; AcetylCoA_hydro; 1.
DR SUPFAM; SSF100950; NagB/RpiA/CoA transferase-like; 2.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000313|EMBL:EZQ12320.1}.
FT DOMAIN 9..215
FT /note="Acetyl-CoA hydrolase/transferase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02550"
FT DOMAIN 321..464
FT /note="Acetyl-CoA hydrolase/transferase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13336"
FT ACT_SITE 289
FT /note="5-glutamyl coenzyme A thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR617821-1"
FT BINDING 379
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /evidence="ECO:0000256|PIRSR:PIRSR617821-2"
FT BINDING 383
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /evidence="ECO:0000256|PIRSR:PIRSR617821-2"
FT BINDING 403
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /evidence="ECO:0000256|PIRSR:PIRSR617821-2"
SQ SEQUENCE 505 AA; 54956 MW; A6C99D4B3DC78D1F CRC64;
MSLDRIRLES LHEKVISAEQ ASTFIEDGMT VGMSGFTRAG EAKAVPLALV KRAHTNPLKI
TLITGASLGN DLDKQLTEAG VLARRLPFQV DNTLRKAINK GEVMFIDQHL SETVEQMRNK
QLKKPDIAVI EAVAITEDGG IIPTTSVGNS ASFAIFAEKV IVEINTNLSL AFEGLHDIYI
PSYRPTRQPI PLTQVDERIG THAINIDPAK IVGIVFNSEF HDSPSTVTAP DDETQAIANH
LIEFFEKEVA DERLPKNLGP LQAGIGSIAN AVLTGLKESN FEDLIMYSEV LQDCTFELID
AGKMKFASGS SITLSARYGE KVFNNLEQYK DKLVLRPQEI SNHPELVRRL GIIGINTALE
FDIYGNVNST HVCGSKMMNG IGGSGDFARN AHIAIFVTKS IAKGGDISSV VPMASHVDHT
GHDVDVLVTE QGLADLRGLA PRERARAIID NCVHPLYKDA LNDYFDRACA KGGQTPHLLT
EALSWHSNFE ETGHMLSAPA EAKSA
//
