ID   A0A058Z0C9_FONAL        Unreviewed;      1042 AA.
AC   A0A058Z0C9;
DT   09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT   09-JUL-2014, sequence version 1.
DT   24-JAN-2024, entry version 42.
DE   RecName: Full=Importin N-terminal domain-containing protein {ECO:0000259|PROSITE:PS50166};
GN   ORFNames=H696_05823 {ECO:0000313|EMBL:KCV67715.1};
OS   Fonticula alba (Slime mold).
OC   Eukaryota; Rotosphaerida; Fonticulaceae; Fonticula.
OX   NCBI_TaxID=691883 {ECO:0000313|EMBL:KCV67715.1};
RN   [1] {ECO:0000313|EMBL:KCV67715.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 38817 {ECO:0000313|EMBL:KCV67715.1};
RG   The Broad Institute Genomics Platform;
RA   Russ C., Cuomo C., Burger G., Gray M.W., Holland P.W.H., King N.,
RA   Lang F.B.F., Roger A.J., Ruiz-Trillo I., Brown M., Walker B., Young S.,
RA   Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W.,
RA   Alvarado L., Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J.,
RA   Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A.,
RA   Ireland A., Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W.,
RA   Priest M., Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J.,
RA   Nusbaum C., Birren B.;
RT   "The Genome Sequence of Fonticula alba ATCC 38817.";
RL   Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the exportin family.
CC       {ECO:0000256|ARBA:ARBA00009466}.
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DR   EMBL; KB932214; KCV67715.1; -; Genomic_DNA.
DR   RefSeq; XP_009497899.1; XM_009499624.1.
DR   AlphaFoldDB; A0A058Z0C9; -.
DR   STRING; 691883.A0A058Z0C9; -.
DR   EnsemblProtists; KCV67715; KCV67715; H696_05823.
DR   GeneID; 20530548; -.
DR   eggNOG; KOG2020; Eukaryota.
DR   OMA; WAFKHNN; -.
DR   OrthoDB; 169519at2759; -.
DR   Proteomes; UP000030693; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR   GO; GO:0005049; F:nuclear export signal receptor activity; IEA:InterPro.
DR   GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR   GO; GO:0006611; P:protein export from nucleus; IEA:InterPro.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR041123; CRM1_repeat.
DR   InterPro; IPR041235; Exp1_repeat_2.
DR   InterPro; IPR013598; Exportin-1/Importin-b-like.
DR   InterPro; IPR001494; Importin-beta_N.
DR   InterPro; IPR045065; XPO1/5.
DR   InterPro; IPR014877; XPO1_C_dom.
DR   InterPro; IPR040485; XPO1_repeat_3.
DR   PANTHER; PTHR11223; EXPORTIN 1/5; 1.
DR   PANTHER; PTHR11223:SF2; EXPORTIN-1; 1.
DR   Pfam; PF08767; CRM1_C; 1.
DR   Pfam; PF18777; CRM1_repeat; 1.
DR   Pfam; PF18784; CRM1_repeat_2; 1.
DR   Pfam; PF18787; CRM1_repeat_3; 1.
DR   Pfam; PF03810; IBN_N; 1.
DR   Pfam; PF08389; Xpo1; 1.
DR   SMART; SM01102; CRM1_C; 1.
DR   SMART; SM00913; IBN_N; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   PROSITE; PS50166; IMPORTIN_B_NT; 1.
PE   3: Inferred from homology;
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW   Reference proteome {ECO:0000313|Proteomes:UP000030693};
KW   Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   DOMAIN          32..98
FT                   /note="Importin N-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS50166"
SQ   SEQUENCE   1042 AA;  118583 MW;  F169A89173FC249B CRC64;
     MEGGPLNVYN LDVSALDQIV KSFHNGTDVM NAQALLVQFQ DHPESWTCVD KILENSTFVP
     TKFLALQIMD KLVQTRWNLI PREQCEGIRN FLVTHAISLA RDEAFMSANA SYMHKLDLVI
     VQIIKQDWPH RWESLIPDLV GSSKTSESIC ENNMIILKLL SEEIFDYSEE QIVSKRVDEL
     KNELANQFAP IFSLCMFILT SASKPSLVLV ALETLLRFLG WIPLGYIFET NLIPFLTEKF
     FVVPQSRNVT LKCLTEIASL KLQQGQGATF VPMIVRLFDS VMEKLPAYLS VETDLASTYN
     NRSGSDQIFI QDLANFFVGL FKEHLSVLES HNPDRLLTAH MYLINISNID DREVFKSCLD
     YWAVLVEQLY REPSMAPSPL LITSSPGPTP RQQFYQQILS HLRVVMINRM VKPEEVLIVE
     EEGEIIREFQ KDTDTIALYK AMQVVLTHLT HLDSEDMEFI MREKLMRLMS NAEWSWSAIN
     KLCWSIGSIS GAMSEPEEKR FLVVVIKELL DLVDLKRGTD NKAVVASNIM YIVGQYPRFL
     RQHWKFLKTV VNKLFEFMHE RHEGVPDMAC DTFIKIASSC RNLFVVAHVN EPGPFINTII
     DSLPATISDL QPQQVQTFYE AVGIMISAAT STEQAHALIH KLMALPNQGW SELLSKIAGD
     ISLLENPTMY KTLANILKTN VSVCSSVGQA FIVHIAHIFR DMMELYPICS QLINNRLQTG
     GPNEPRTPLV RGLRLIKREI LKLFITFFPH CAGDPETVAT SFVPDLLKVT MIDYQNTQPE
     VRDAEVLLLC ASMVDHLKGE VIGKVHPILD AVFECTLSMI SKDFQEYPDH RTGFYRLLRA
     INRHCFEALF TLGQAQFKLF IDSVVWGIKH TMRDIAEMAL HTLQEMLEQF RRKLLAQPGQ
     VTGFYQQYYV SLMQDVFVVL TDSDHKAGFK LQTSILKDMF DIVIDGLMPA QLFDPKAFPD
     NPNMTNVAFL NHYVSDLLAR AFPQVTPAQV KHFVKGLLQK NDPLAFKVLV RDFLISLKQF
     AGQDNQELYV VDEPAADASI AN
//