ID A0A058Z4U7_FONAL Unreviewed; 519 AA.
AC A0A058Z4U7;
DT 09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT 09-JUL-2014, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=Nucleoside transporter {ECO:0008006|Google:ProtNLM};
GN ORFNames=H696_04362 {ECO:0000313|EMBL:KCV68943.1};
OS Fonticula alba (Slime mold).
OC Eukaryota; Rotosphaerida; Fonticulaceae; Fonticula.
OX NCBI_TaxID=691883 {ECO:0000313|EMBL:KCV68943.1};
RN [1] {ECO:0000313|EMBL:KCV68943.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 38817 {ECO:0000313|EMBL:KCV68943.1};
RG The Broad Institute Genomics Platform;
RA Russ C., Cuomo C., Burger G., Gray M.W., Holland P.W.H., King N.,
RA Lang F.B.F., Roger A.J., Ruiz-Trillo I., Brown M., Walker B., Young S.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W.,
RA Alvarado L., Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J.,
RA Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A.,
RA Ireland A., Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W.,
RA Priest M., Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J.,
RA Nusbaum C., Birren B.;
RT "The Genome Sequence of Fonticula alba ATCC 38817.";
RL Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
CC {ECO:0000256|ARBA:ARBA00007965}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KB932207; KCV68943.1; -; Genomic_DNA.
DR RefSeq; XP_009496514.1; XM_009498239.1.
DR AlphaFoldDB; A0A058Z4U7; -.
DR STRING; 691883.A0A058Z4U7; -.
DR EnsemblProtists; KCV68943; KCV68943; H696_04362.
DR GeneID; 20529087; -.
DR eggNOG; KOG1479; Eukaryota.
DR OMA; GSPWTTK; -.
DR OrthoDB; 517168at2759; -.
DR Proteomes; UP000030693; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005337; F:nucleoside transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR002259; Eqnu_transpt.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR10332; EQUILIBRATIVE NUCLEOSIDE TRANSPORTER; 1.
DR PANTHER; PTHR10332:SF90; NUCLEOSIDE TRANSPORTER FUN26; 1.
DR Pfam; PF01733; Nucleoside_tran; 1.
DR PIRSF; PIRSF016379; ENT; 1.
DR PRINTS; PR01130; DERENTRNSPRT.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000030693};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 84..104
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 124..147
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 154..176
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 182..207
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 219..238
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 258..279
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 338..365
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 377..396
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 408..428
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 448..467
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 488..507
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 519 AA; 55841 MW; 62D0FCB751C56DB8 CRC64;
MTSPYDSLNS SYGISNDYDT SGYGQQQHHH HMAHDDPYAA TSGTGGATYS TKYGTYADED
LDLKAAPKTT VADQLGEPPA DPRGIVYGIF LLLGIGMLFP WNVFVNATSF YGLRFAGSPF
SDNFVNFFSI TYNLSNMILI VVVALLVSRL TPRGSVFGAL MAMAGAFVVQ TALVYVEMDP
TLFFVITLLL VVVCGGSGAF FQSGIFAITA SFPGKYTSAI MIGQGVAGIV VSISQLLTQL
ISDPNAGSAD DGSAELSALL YFLVAVFLLI ACIFSFATLP RMALFTYFTE KAARLTGTGS
DVAPDSDTAP LIPTDPVDED GLALPAQPAG YMAIFREIWF MPVGVFFTFF LTLSLFPMFI
AATAPSTESD SRLFNDLFVS FGFLVFNIGD ITGRFLPTLY VAPAKSLLPM SLLRLVFIPL
FLFCNVVLYD PTGQPIESPV PVIFANDWVF WGILLVFAIS NGYVANVQMM LGAQQVSDMR
NLPKASNLMV SALVAGLLFG SMASFGLRGI LCSCNPFIE
//
