ID A0A058Z5P1_FONAL Unreviewed; 1124 AA.
AC A0A058Z5P1;
DT 09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT 09-JUL-2014, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=SEC7 domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=H696_03856 {ECO:0000313|EMBL:KCV69426.1};
OS Fonticula alba (Slime mold).
OC Eukaryota; Rotosphaerida; Fonticulaceae; Fonticula.
OX NCBI_TaxID=691883 {ECO:0000313|EMBL:KCV69426.1};
RN [1] {ECO:0000313|EMBL:KCV69426.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 38817 {ECO:0000313|EMBL:KCV69426.1};
RG The Broad Institute Genomics Platform;
RA Russ C., Cuomo C., Burger G., Gray M.W., Holland P.W.H., King N.,
RA Lang F.B.F., Roger A.J., Ruiz-Trillo I., Brown M., Walker B., Young S.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W.,
RA Alvarado L., Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J.,
RA Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A.,
RA Ireland A., Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W.,
RA Priest M., Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J.,
RA Nusbaum C., Birren B.;
RT "The Genome Sequence of Fonticula alba ATCC 38817.";
RL Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KB932206; KCV69426.1; -; Genomic_DNA.
DR RefSeq; XP_009495991.1; XM_009497716.1.
DR AlphaFoldDB; A0A058Z5P1; -.
DR STRING; 691883.A0A058Z5P1; -.
DR EnsemblProtists; KCV69426; KCV69426; H696_03856.
DR GeneID; 20528581; -.
DR eggNOG; KOG0930; Eukaryota.
DR OrthoDB; 204547at2759; -.
DR Proteomes; UP000030693; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0012505; C:endomembrane system; IEA:UniProt.
DR GO; GO:0043231; C:intracellular membrane-bounded organelle; IEA:UniProt.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0051641; P:cellular localization; IEA:UniProt.
DR GO; GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:UniProt.
DR CDD; cd00171; Sec7; 1.
DR Gene3D; 1.10.220.20; -; 1.
DR Gene3D; 1.10.1000.11; Arf Nucleotide-binding Site Opener,domain 2; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR023394; Sec7_C_sf.
DR InterPro; IPR000904; Sec7_dom.
DR InterPro; IPR035999; Sec7_dom_sf.
DR PANTHER; PTHR10663; GUANYL-NUCLEOTIDE EXCHANGE FACTOR; 1.
DR PANTHER; PTHR10663:SF406; MIP16918P; 1.
DR Pfam; PF00169; PH; 1.
DR Pfam; PF01369; Sec7; 1.
DR SMART; SM00233; PH; 1.
DR SMART; SM00222; Sec7; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF48425; Sec7 domain; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
DR PROSITE; PS50190; SEC7; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000030693}.
FT DOMAIN 481..670
FT /note="SEC7"
FT /evidence="ECO:0000259|PROSITE:PS50190"
FT DOMAIN 687..766
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 1..38
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 50..177
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 288..324
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 344..430
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 761..848
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 860..944
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 964..1026
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 23..38
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 61..99
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 114..128
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 129..154
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 344..368
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 766..784
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 802..848
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 913..940
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 969..993
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1124 AA; 115287 MW; D86F6D26011CE5CA CRC64;
MSPEAGAAHH QPPAAPPPEG AEASFPNSSN TSSSSSTTAI TAASVAIADP AGLPLPDSTP
CSSMPDLTSS TITSTTATTT TTTTTTGSAP GSSPPQSFFH PGPGNLELTD SDSDEDGANC
HEVLSDDESD PVSSTSSGQM APSIPTTPSA VSIPLPDGDS SDHSSPDLPP LSPVTYLSDD
TQVVGAPAMP VTSCPISIPR SPSDSPFRLR RHLSDDHSLF SDTSAEDILV PLASGDDCVG
PLPGDSGGLM DDLFPSLDGM VSGDAEATTA ITSTPAASVS VTATATGDVA GDAGVEAGPS
PDSRSPHPPM EASSPGGAGG ARARASSGIL SGFSLRRSAG RFGSLTRGAS TRTSVATTTD
SAEASPTAPR SPTALDLPSA PAPASGEGDA PLKRASSSLG IMSTSLPVGG GGGGGAGGLS
SPLSSSPVVT ASPTLRSPGM HPLSPGLAHG GISRHAGTRT SISLLSPSSP ISLLDSPDFE
AAEAEQRLRR HWAIARSKFS ADPLSAFDYL KDVGLIDGSA LSIAQYLAGP ENNFLNKEAI
GEFLGGGDAF NVEVLSLFAG LQEFHSLSFD NALRQFLSTF RLPGEAQKID RMMERFASRF
HENNPGVFAR SDTAYILAFS TIMLNTDLHN PAIRNKITKD AFIRNNRGID NGADLPESFL
TNLYDTILKE EIKLNDAASR ERLTFFNPER EGYLWKQGGR VKTWKKRFFI LTGNCVYYFK
RQGDPRPCGI IPLENLRVCE AGQSRDKKTR FRFQLYHPDN PPAHLLAQQP KQQAQPSTRS
GAVSPLPGES PLSPDAAPPA SPSSGGPSSA SSFPSSLSSF TSSLSSSLGF GSSSGPQSSP
DLILLSPSRS NASTLGRYNS LLSVQPPSEQ GPASPSAAPT PSPVVSPSGV ASPIEHLPDC
QVVRPIPPPD ASEQGTSPSE QGTAPSEQGT APSEQGTAPS GEQPAALVEC PGCMAEVAAG
PGCDESPLNA SPSAGSSLDA SGASSSLSLS QVGGIEPPTD VAPVASIPIS GPVPQTPGAG
PTQAPIVASS TGASATASPL ASSTSSLLSV GLLSRTRSMS MTIKAAKHAG DGKMVEGHHS
YYLLGCDSED ARHDWICSLN AHMQQIPIYI LMRERREKVT GQVS
//
