ID A0A058ZAW2_FONAL Unreviewed; 677 AA.
AC A0A058ZAW2;
DT 09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT 09-JUL-2014, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=Choline/carnitine acyltransferase domain-containing protein {ECO:0000259|Pfam:PF00755};
GN ORFNames=H696_02500 {ECO:0000313|EMBL:KCV71560.1};
OS Fonticula alba (Slime mold).
OC Eukaryota; Rotosphaerida; Fonticulaceae; Fonticula.
OX NCBI_TaxID=691883 {ECO:0000313|EMBL:KCV71560.1};
RN [1] {ECO:0000313|EMBL:KCV71560.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 38817 {ECO:0000313|EMBL:KCV71560.1};
RG The Broad Institute Genomics Platform;
RA Russ C., Cuomo C., Burger G., Gray M.W., Holland P.W.H., King N.,
RA Lang F.B.F., Roger A.J., Ruiz-Trillo I., Brown M., Walker B., Young S.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W.,
RA Alvarado L., Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J.,
RA Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A.,
RA Ireland A., Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W.,
RA Priest M., Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J.,
RA Nusbaum C., Birren B.;
RT "The Genome Sequence of Fonticula alba ATCC 38817.";
RL Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the carnitine/choline acetyltransferase family.
CC {ECO:0000256|ARBA:ARBA00005232}.
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DR EMBL; KB932203; KCV71560.1; -; Genomic_DNA.
DR RefSeq; XP_009494683.1; XM_009496408.1.
DR AlphaFoldDB; A0A058ZAW2; -.
DR STRING; 691883.A0A058ZAW2; -.
DR EnsemblProtists; KCV71560; KCV71560; H696_02500.
DR GeneID; 20527225; -.
DR eggNOG; KOG3717; Eukaryota.
DR OMA; MAMSSYE; -.
DR OrthoDB; 1429709at2759; -.
DR Proteomes; UP000030693; Unassembled WGS sequence.
DR GO; GO:0016746; F:acyltransferase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 1.
DR Gene3D; 3.30.559.70; Choline/Carnitine o-acyltransferase, domain 2; 1.
DR InterPro; IPR000542; Carn_acyl_trans.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR039551; Cho/carn_acyl_trans.
DR InterPro; IPR042231; Cho/carn_acyl_trans_2.
DR PANTHER; PTHR22589:SF115; CARNITINE O-ACETYLTRANSFERASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR22589; CARNITINE O-ACYLTRANSFERASE; 1.
DR Pfam; PF00755; Carn_acyltransf; 1.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 2.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315};
KW Reference proteome {ECO:0000313|Proteomes:UP000030693};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 79..653
FT /note="Choline/carnitine acyltransferase"
FT /evidence="ECO:0000259|Pfam:PF00755"
FT ACT_SITE 380
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR600542-1"
SQ SEQUENCE 677 AA; 73927 MW; EB556B5AB6440751 CRC64;
MMHRLPRASR VLSGPARAAR TLIGPGAAQC AIRGLATTTA GAPAAGSLPA SHFVPADPRV
LPRDDLTPLW KAQSHLPPLP LHRLEQSVRG VLSNVDALLG PAAVAEVVPL AETFTDEDGL
GPELHARLER LAQTEPGNNW FLRFWNQHAY FQPRASLPTN VSYFYSYTDD QSFRTPLARA
ASLAHRALQF RWALDQKLYP AEYTRDGKPL CMLQFHHLLN SCRIPRPGAD TFVQRDRAVP
GNHLGLVVLR GGHVFHLDLI CPDTGVMFPE STLAKSLETI TERAGQLGPA KYPIGLLTAI
DRDQSAKGLD LLEQASPKNA AHLACVRNAA LVLCLDDTSP DTPDQVCREI WHSDGRNRFY
DHSVQIICFA NGKAGHINEH SLADGSTSIR VAEAATGRGQ GADRLNEAQA LGFDPTGATS
GTLATSSLRA PRHLDFDLTD DLRAQITTAA TAVREDAGRR DMRQFDFRGF GSAHISKRLH
QSPDAFVQMA MQLAYRRLHG MACSTYETGQ TRLFAGGRTE AIRTVSHESV MWTTAMMDDT
FNPEVRAYLL DNALRRHATT TRAVVEGSGF DRHLSALKYV LEPGETDPFL ESAILDASRQ
WTLSTSQLVS PAVNGYGWGQ VCDQGYGIPY LVQADSLRFS VACLSGYARA ADMNEAIGAA
LEDMNQLLLA HPPPARV
//
