ID   A0A058ZD67_FONAL        Unreviewed;       416 AA.
AC   A0A058ZD67;
DT   09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT   09-JUL-2014, sequence version 1.
DT   27-MAR-2024, entry version 45.
DE   SubName: Full=26S protease regulatory subunit 8 {ECO:0000313|EMBL:KCV71382.1};
GN   ORFNames=H696_02333 {ECO:0000313|EMBL:KCV71382.1};
OS   Fonticula alba (Slime mold).
OC   Eukaryota; Rotosphaerida; Fonticulaceae; Fonticula.
OX   NCBI_TaxID=691883 {ECO:0000313|EMBL:KCV71382.1};
RN   [1] {ECO:0000313|EMBL:KCV71382.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 38817 {ECO:0000313|EMBL:KCV71382.1};
RG   The Broad Institute Genomics Platform;
RA   Russ C., Cuomo C., Burger G., Gray M.W., Holland P.W.H., King N.,
RA   Lang F.B.F., Roger A.J., Ruiz-Trillo I., Brown M., Walker B., Young S.,
RA   Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W.,
RA   Alvarado L., Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J.,
RA   Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A.,
RA   Ireland A., Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W.,
RA   Priest M., Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J.,
RA   Nusbaum C., Birren B.;
RT   "The Genome Sequence of Fonticula alba ATCC 38817.";
RL   Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC       Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the AAA ATPase family.
CC       {ECO:0000256|ARBA:ARBA00006914, ECO:0000256|RuleBase:RU003651}.
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DR   EMBL; KB932203; KCV71382.1; -; Genomic_DNA.
DR   RefSeq; XP_009494505.1; XM_009496230.1.
DR   AlphaFoldDB; A0A058ZD67; -.
DR   STRING; 691883.A0A058ZD67; -.
DR   EnsemblProtists; KCV71382; KCV71382; H696_02333.
DR   GeneID; 20527058; -.
DR   eggNOG; KOG0728; Eukaryota.
DR   OMA; TANCRVA; -.
DR   OrthoDB; 360215at2759; -.
DR   Proteomes; UP000030693; Unassembled WGS sequence.
DR   GO; GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.8.60; -; 1.
DR   Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR041569; AAA_lid_3.
DR   InterPro; IPR003959; ATPase_AAA_core.
DR   InterPro; IPR003960; ATPase_AAA_CS.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR032501; Prot_ATP_ID_OB_2nd.
DR   PANTHER; PTHR23073; 26S PROTEASOME REGULATORY SUBUNIT; 1.
DR   PANTHER; PTHR23073:SF166; 26S PROTEASOME REGULATORY SUBUNIT 8; 1.
DR   Pfam; PF00004; AAA; 1.
DR   Pfam; PF17862; AAA_lid_3; 1.
DR   Pfam; PF16450; Prot_ATP_ID_OB_C; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS00674; AAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|RuleBase:RU003651};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Hydrolase {ECO:0000313|EMBL:KCV71382.1};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU003651};
KW   Protease {ECO:0000313|EMBL:KCV71382.1};
KW   Proteasome {ECO:0000256|ARBA:ARBA00022942};
KW   Reference proteome {ECO:0000313|Proteomes:UP000030693}.
FT   DOMAIN          188..331
FT                   /note="AAA+ ATPase"
FT                   /evidence="ECO:0000259|SMART:SM00382"
FT   COILED          34..75
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   416 AA;  45648 MW;  34D384B93F1DBE67 CRC64;
     MSSLAMSLAS AVPSGTDAAG ANSDDLAAYF RSRIEDLQVA IHEKTQNLRR LEAQRNELNS
     KVRSLREELQ LLQEPGSYVG EVVKVMGSDR VLVKVHPEGK YLVKVDKAID ISTLTATTRV
     ALRNDSYTLH KILPNKIDPL VSLMMVEKVP DSTYDMIGGL DKQIREIKEV IELPIQHPEL
     FEALGIFQPK GVLLYGPPGT GKTLLARAVA HHTACTFIRV SGSELVQKYI GEGSRMVREL
     FVLAREHAPS IIFMDEIDSI GSSRGDGGGG GKGGGDSEVQ RTMLELLNQL DGFEPNNNIK
     VIMATNRIDI LDDALLRPGR IDRKIEFPPP NDAARVDILK IHSRRMNLAR DIDLNAIASK
     MPGASGAECR GVCTEAGMVA LRERRLHVTH ADFEAAVAKV MRRDADANTS INKLFI
//