ID A0A059A750_EUCGR Unreviewed; 362 AA.
AC A0A059A750;
DT 09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT 09-JUL-2014, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE RecName: Full=Cysteine proteinase {ECO:0008006|Google:ProtNLM};
GN ORFNames=EUGRSUZ_K02769 {ECO:0000313|EMBL:KCW49190.1};
OS Eucalyptus grandis (Flooded gum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Myrtales; Myrtaceae; Myrtoideae; Eucalypteae; Eucalyptus.
OX NCBI_TaxID=71139 {ECO:0000313|EMBL:KCW49190.1};
RN [1] {ECO:0000313|EMBL:KCW49190.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf extractions {ECO:0000313|EMBL:KCW49190.1};
RA Schmutz J., Hayes R., Myburg A., Tuskan G., Grattapaglia D., Rokhsar D.S.;
RT "The genome of Eucalyptus grandis.";
RL Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase C1 family.
CC {ECO:0000256|ARBA:ARBA00008455}.
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DR EMBL; KK198763; KCW49190.1; -; Genomic_DNA.
DR RefSeq; XP_010037483.1; XM_010039181.2.
DR AlphaFoldDB; A0A059A750; -.
DR MEROPS; C01.010; -.
DR MEROPS; I29.003; -.
DR EnsemblPlants; KCW49190; KCW49190; EUGRSUZ_K02769.
DR GeneID; 104426207; -.
DR Gramene; KCW49190; KCW49190; EUGRSUZ_K02769.
DR KEGG; egr:104426207; -.
DR eggNOG; KOG1543; Eukaryota.
DR InParanoid; A0A059A750; -.
DR OMA; VYYDEEC; -.
DR OrthoDB; 5472443at2759; -.
DR GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR GO; GO:0004197; F:cysteine-type endopeptidase activity; IBA:GO_Central.
DR GO; GO:0051603; P:proteolysis involved in protein catabolic process; IBA:GO_Central.
DR CDD; cd02248; Peptidase_C1A; 1.
DR Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR025661; Pept_asp_AS.
DR InterPro; IPR000169; Pept_cys_AS.
DR InterPro; IPR025660; Pept_his_AS.
DR InterPro; IPR013128; Peptidase_C1A.
DR InterPro; IPR000668; Peptidase_C1A_C.
DR InterPro; IPR039417; Peptidase_C1A_papain-like.
DR InterPro; IPR013201; Prot_inhib_I29.
DR PANTHER; PTHR12411; CYSTEINE PROTEASE FAMILY C1-RELATED; 1.
DR PANTHER; PTHR12411:SF1001; KDEL-TAILED CYSTEINE ENDOPEPTIDASE CEP1; 1.
DR Pfam; PF08246; Inhibitor_I29; 1.
DR Pfam; PF00112; Peptidase_C1; 1.
DR PRINTS; PR00705; PAPAIN.
DR SMART; SM00848; Inhibitor_I29; 1.
DR SMART; SM00645; Pept_C1; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR PROSITE; PS00640; THIOL_PROTEASE_ASN; 1.
DR PROSITE; PS00139; THIOL_PROTEASE_CYS; 1.
DR PROSITE; PS00639; THIOL_PROTEASE_HIS; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Protease {ECO:0000256|ARBA:ARBA00022670}; Signal {ECO:0000256|SAM:SignalP};
KW Thiol protease {ECO:0000256|ARBA:ARBA00022807}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..362
FT /note="Cysteine proteinase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018765690"
FT DOMAIN 40..95
FT /note="Cathepsin propeptide inhibitor"
FT /evidence="ECO:0000259|SMART:SM00848"
FT DOMAIN 128..344
FT /note="Peptidase C1A papain C-terminal"
FT /evidence="ECO:0000259|SMART:SM00645"
SQ SEQUENCE 362 AA; 40242 MW; B171F955612533BC CRC64;
MELNKLFLVA LALVSILGIA ESFDFHEREL ASDDSLWDLY ERWRSHHTVS RSLHDKNERF
NVFKHNVMHV HRVNKQDKPY KLKLNKFADM TNHEFRSLYA GSKINHHRMF RGAQRGSESF
MYKDFAPVPP SVDWRKKGAV ADVKNQGHCG SCWAFSTVAA VEGINYLRTN KLLSLSEQEL
VDCDNTQNQG CNGGLMDIAF EFIKQKGGIT SESNYPYQAS NGTCDAAKEN SPVVSIDGHE
NVPANDEDAL QKAVANQPVS VAIEASGADF QFYSEGVFTG SCGTQLDHGV AIVGYGSTLQ
GTKYWIVRNS WGPEWGEKGY LRMERGIEAK EGLCGIAMEA SYPIKNSSDN PAGVSSPVKD
EL
//
