ID   A0A059AFW9_EUCGR        Unreviewed;       189 AA.
AC   A0A059AFW9;
DT   09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT   09-JUL-2014, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   RecName: Full=Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding domain-containing protein {ECO:0000259|Pfam:PF02882};
GN   ORFNames=EUGRSUZ_J01713 {ECO:0000313|EMBL:KCW52290.1};
OS   Eucalyptus grandis (Flooded gum).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Myrtales; Myrtaceae; Myrtoideae; Eucalypteae; Eucalyptus.
OX   NCBI_TaxID=71139 {ECO:0000313|EMBL:KCW52290.1};
RN   [1] {ECO:0000313|EMBL:KCW52290.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Leaf extractions {ECO:0000313|EMBL:KCW52290.1};
RA   Schmutz J., Hayes R., Myburg A., Tuskan G., Grattapaglia D., Rokhsar D.S.;
RT   "The genome of Eucalyptus grandis.";
RL   Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KK198762; KCW52290.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A059AFW9; -.
DR   STRING; 71139.A0A059AFW9; -.
DR   EnsemblPlants; KCW52290; KCW52290; EUGRSUZ_J01713.
DR   Gramene; KCW52290; KCW52290; EUGRSUZ_J01713.
DR   eggNOG; KOG0089; Eukaryota.
DR   InParanoid; A0A059AFW9; -.
DR   OMA; TSCEEIF; -.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0004477; F:methenyltetrahydrofolate cyclohydrolase activity; IBA:GO_Central.
DR   GO; GO:0004488; F:methylenetetrahydrofolate dehydrogenase (NADP+) activity; IBA:GO_Central.
DR   GO; GO:0035999; P:tetrahydrofolate interconversion; IBA:GO_Central.
DR   CDD; cd01080; NAD_bind_m-THF_DH_Cyclohyd; 1.
DR   Gene3D; 3.40.50.10860; Leucine Dehydrogenase, chain A, domain 1; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR000672; THF_DH/CycHdrlase.
DR   InterPro; IPR020631; THF_DH/CycHdrlase_NAD-bd_dom.
DR   PANTHER; PTHR48099; C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC-RELATED; 1.
DR   PANTHER; PTHR48099:SF13; METHENYLTETRAHYDROFOLATE CYCLOHYDROLASE; 1.
DR   Pfam; PF02882; THF_DHG_CYH_C; 1.
DR   PRINTS; PR00085; THFDHDRGNASE.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
FT   DOMAIN          47..161
FT                   /note="Tetrahydrofolate dehydrogenase/cyclohydrolase
FT                   NAD(P)-binding"
FT                   /evidence="ECO:0000259|Pfam:PF02882"
SQ   SEQUENCE   189 AA;  21198 MW;  1352329E842C86CE CRC64;
     MRYYHSFNTS CEEIFTVMPP NVMFAQHVDE ERIINFVSPE KDVDGFHPLN MGNLAMKGRE
     PLFIPCAPKS CIELLLRSGV EIMGKRAVVV GRSKIVGLPT SLLLQRHHAT VSTVHSFTKN
     PEQITREADI VIADVGIPNL IRGSWLKPGA VVVDMGTNQV QVGILKVRHQ WHSQTVWPHL
     NANLDCNVR
//