ID A0A059AHV4_EUCGR Unreviewed; 714 AA.
AC A0A059AHV4;
DT 09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT 09-JUL-2014, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE RecName: Full=Eukaryotic translation initiation factor 3 subunit B {ECO:0000256|HAMAP-Rule:MF_03001, ECO:0000256|PIRNR:PIRNR036424};
DE Short=eIF3b {ECO:0000256|HAMAP-Rule:MF_03001, ECO:0000256|PIRNR:PIRNR036424};
DE AltName: Full=eIF-3-eta {ECO:0000256|HAMAP-Rule:MF_03001};
DE AltName: Full=eIF3 p110 {ECO:0000256|HAMAP-Rule:MF_03001};
GN ORFNames=EUGRSUZ_J02249 {ECO:0000313|EMBL:KCW52935.1};
OS Eucalyptus grandis (Flooded gum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Myrtales; Myrtaceae; Myrtoideae; Eucalypteae; Eucalyptus.
OX NCBI_TaxID=71139 {ECO:0000313|EMBL:KCW52935.1};
RN [1] {ECO:0000313|EMBL:KCW52935.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf extractions {ECO:0000313|EMBL:KCW52935.1};
RA Schmutz J., Hayes R., Myburg A., Tuskan G., Grattapaglia D., Rokhsar D.S.;
RT "The genome of Eucalyptus grandis.";
RL Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Component of the eukaryotic translation initiation factor 3
CC (eIF-3) complex, which is involved in protein synthesis and, together
CC with other initiation factors, stimulates binding of mRNA and
CC methionyl-tRNAi to the 40S ribosome. {ECO:0000256|PIRNR:PIRNR036424}.
CC -!- FUNCTION: RNA-binding component of the eukaryotic translation
CC initiation factor 3 (eIF-3) complex, which is involved in protein
CC synthesis of a specialized repertoire of mRNAs and, together with other
CC initiation factors, stimulates binding of mRNA and methionyl-tRNAi to
CC the 40S ribosome. The eIF-3 complex specifically targets and initiates
CC translation of a subset of mRNAs involved in cell proliferation.
CC {ECO:0000256|HAMAP-Rule:MF_03001}.
CC -!- SUBUNIT: Component of the eukaryotic translation initiation factor 3
CC (eIF-3) complex. {ECO:0000256|HAMAP-Rule:MF_03001,
CC ECO:0000256|PIRNR:PIRNR036424}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_03001,
CC ECO:0000256|PIRNR:PIRNR036424}.
CC -!- SIMILARITY: Belongs to the eIF-3 subunit B family. {ECO:0000256|HAMAP-
CC Rule:MF_03001, ECO:0000256|PIRNR:PIRNR036424}.
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DR EMBL; KK198762; KCW52935.1; -; Genomic_DNA.
DR EMBL; KK198762; KCW52936.1; -; Genomic_DNA.
DR RefSeq; XP_010033332.1; XM_010035030.2.
DR RefSeq; XP_018719732.1; XM_018864187.1.
DR STRING; 71139.A0A059AHV4; -.
DR EnsemblPlants; KCW52935; KCW52935; EUGRSUZ_J02249.
DR EnsemblPlants; KCW52936; KCW52936; EUGRSUZ_J02249.
DR GeneID; 104422645; -.
DR Gramene; KCW52935; KCW52935; EUGRSUZ_J02249.
DR Gramene; KCW52936; KCW52936; EUGRSUZ_J02249.
DR KEGG; egr:104422645; -.
DR eggNOG; KOG2314; Eukaryota.
DR OMA; LWGGPQF; -.
DR OrthoDB; 5479191at2759; -.
DR GO; GO:0016282; C:eukaryotic 43S preinitiation complex; IEA:UniProtKB-UniRule.
DR GO; GO:0033290; C:eukaryotic 48S preinitiation complex; IEA:UniProtKB-UniRule.
DR GO; GO:0005852; C:eukaryotic translation initiation factor 3 complex; IBA:GO_Central.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-UniRule.
DR GO; GO:0031369; F:translation initiation factor binding; IEA:InterPro.
DR GO; GO:0001732; P:formation of cytoplasmic translation initiation complex; IEA:UniProtKB-UniRule.
DR GO; GO:0006413; P:translational initiation; IBA:GO_Central.
DR CDD; cd12278; RRM_eIF3B; 1.
DR Gene3D; 3.30.70.330; -; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR HAMAP; MF_03001; eIF3b; 1.
DR InterPro; IPR011400; EIF3B.
DR InterPro; IPR034363; eIF3B_RRM.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR InterPro; IPR013979; TIF_beta_prop-like.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR PANTHER; PTHR14068; EUKARYOTIC TRANSLATION INITIATION FACTOR 3 EIF3 -RELATED; 1.
DR PANTHER; PTHR14068:SF0; EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT B; 1.
DR Pfam; PF08662; eIF2A; 1.
DR Pfam; PF00076; RRM_1; 1.
DR PIRSF; PIRSF036424; eIF3b; 1.
DR SMART; SM00360; RRM; 1.
DR SUPFAM; SSF82171; DPP6 N-terminal domain-like; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR PROSITE; PS50102; RRM; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|HAMAP-Rule:MF_03001, ECO:0000256|PIRNR:PIRNR036424};
KW Initiation factor {ECO:0000256|HAMAP-Rule:MF_03001,
KW ECO:0000256|PIRNR:PIRNR036424};
KW Protein biosynthesis {ECO:0000256|HAMAP-Rule:MF_03001,
KW ECO:0000256|PIRNR:PIRNR036424};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|HAMAP-
KW Rule:MF_03001}.
FT DOMAIN 56..143
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 669..695
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 714 AA; 82375 MW; D1F5ABC25CB3C95E CRC64;
MADALIEERA ALMGIDMSQI DLDSVQLPPG EDFGIISDDD DLYQEDTLEL DTGLGNIIIV
DNLPVVPREK FDKLEGVVRK IYSQIGVIKD DGLWMPVDPD TQKTLGYCFI EYNTAQEAEL
AKEKTNGYKL DRSHIFAVSM FEDFDRFMRV PDEWAPPETK PYTPGENLQQ WLTDEKARDQ
FVIRAGSDTE VLWNDARQLK PEPVHRRAFW TESFVQWSPL GTYLATVHRQ GSAVWGGAST
FNRLMRYAHP QVKLIDFSPS EKYLVTYSSH EPSNPRDPQR VVINIFDVRT GKIMRDFKGS
ADDFAVGGTG AVTGVSWPVF RWGGGRDDKY FARIGKSVVS VYETETFSLI DKKSLKVENV
MDFNWSPTDP ILALYVPELG GGNQPARVSL VQIPSKEELR QKNLFSVSDC KMYWQSNGDY
LAVKVDRYTK TKKSTYTGFE LFRIKERDIP IEVLELENKN DKIIAFAWEP KGHRFAVIHG
DGPRPDVSFY SMRSGNNTGR VSKLTTLKGK QANFLFWSPA GRYIILAGLK NFNGQLEFYN
VDELETMATA EHFMATDIEW DPTGRYVATA VTSVHEMENG FNIWSFNGKL LYRILKDHFF
QFLWRPRPPS LLSPEKEEEI AKNLKKYSKK YEAEDQDVSM LLSEQDREKR KMLKDEWEKW
VSRWKQMQEE EKLERQNLRD GEASDEEEEY EAKEVEVEEL LDVSEEVLSF DYEE
//
