ID A0A059APH8_EUCGR Unreviewed; 1318 AA.
AC A0A059APH8;
DT 09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT 09-JUL-2014, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=SSD domain-containing protein {ECO:0000259|PROSITE:PS50156};
GN ORFNames=EUGRSUZ_I01521 {ECO:0000313|EMBL:KCW55669.1};
OS Eucalyptus grandis (Flooded gum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Myrtales; Myrtaceae; Myrtoideae; Eucalypteae; Eucalyptus.
OX NCBI_TaxID=71139 {ECO:0000313|EMBL:KCW55669.1};
RN [1] {ECO:0000313|EMBL:KCW55669.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf extractions {ECO:0000313|EMBL:KCW55669.1};
RA Schmutz J., Hayes R., Myburg A., Tuskan G., Grattapaglia D., Rokhsar D.S.;
RT "The genome of Eucalyptus grandis.";
RL Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the patched family.
CC {ECO:0000256|ARBA:ARBA00005585}.
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DR EMBL; KK198761; KCW55669.1; -; Genomic_DNA.
DR STRING; 71139.A0A059APH8; -.
DR EnsemblPlants; KCW55669; KCW55669; EUGRSUZ_I01521.
DR Gramene; KCW55669; KCW55669; EUGRSUZ_I01521.
DR InParanoid; A0A059APH8; -.
DR OMA; VSLHCQN; -.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0005319; F:lipid transporter activity; IEA:InterPro.
DR GO; GO:0032934; F:sterol binding; IBA:GO_Central.
DR GO; GO:0015918; P:sterol transport; IBA:GO_Central.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR004765; NPC1-like.
DR InterPro; IPR032190; NPC1_N.
DR InterPro; IPR003392; Ptc/Disp.
DR InterPro; IPR000731; SSD.
DR NCBIfam; TIGR00917; 2A060601; 1.
DR PANTHER; PTHR45727; NPC INTRACELLULAR CHOLESTEROL TRANSPORTER 1; 1.
DR PANTHER; PTHR45727:SF8; PATCHED FAMILY PROTEIN; 1.
DR Pfam; PF16414; NPC1_N; 1.
DR Pfam; PF02460; Patched; 2.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
DR PROSITE; PS50156; SSD; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Membrane {ECO:0000256|SAM:Phobius}; Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 294..314
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 387..408
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 439..456
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 654..672
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 687..710
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 722..742
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 762..783
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 790..816
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 867..888
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1140..1163
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1170..1190
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1202..1223
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1235..1260
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1272..1296
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 653..816
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
FT REGION 325..345
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1318 AA; 144774 MW; 0847FDD6EE02A9CA CRC64;
MAISKRDLSA RSFRAFLALF QVIGYASLLS CQGIEMEMLS SSGAMSLERH SEDYCAMYDI
CGERSDGKVL NCPYGSSSVK PDELFSAKIQ SLCPTISGNV CCTETQFETL RAQVQQAIPF
LVGCPACLRN FLNLFCELSC SPNQSLFINV TSVTEIDGNM AVDAIDFFVT DTFGEMLYDS
CKEVKFGTMN TRAIDFIGAG AKSYREWFSF IGQKADLGFP GSPYSISFKS NVPESSGMEL
MNVSSYSCGD TSLGCSCGDC PASPFCSDAE PPSPHKRDSC SISIGSLEVA CLELSLGILY
IVFISAFFGW SSCYGRRENR RPAPIRKPLL DPINDGESSS VLQKDKERPV KMEEMASAES
NMVQFSSVQG YISSFYRSYG LWIARNATLV LCSSLAIVLL LCLGLLRFEV ETRPEKLWVG
PGSKAAEEKQ FFDSHLAPFY RIEQLFSIVS IVIYLLHDMM YLQLILATVP DVEGGRQPSI
VTDRNIRLLF DLQQKVDGIR VNISGKMVSL ADICLKPLGN DCATQSILQY YKMDPDSYNM
YGGVTHAEYC FQHYTSADTC MSAFEAPLDP STALGGFSGN NYSEASAFVV TYPVNNAMDD
ATDENRMALA WEKAFIQLAK EELLPSAESN NLTLSFSSES SIEEELKRES TADVLTIVVS
YLVMFAYISF TLGDPLSSST FYISSKVLLG LAGVLIVMLS VLGSVGFFSA IGIKSTLIIM
EVIPFLVLAV GVDNMCILVH AVKRQPSDMS LEERISSALV EVGPSITLAS LSEVLAFAVG
AFIPMPACRV FSMFAALAIL LDFLLQVTAF VALIVFDFTR AENNRVDCLP CIKINSPGVS
DEVSHQRNPG LLVRYMKDVH ARILGHWAVK IFVVAAFVAF SLASIALCTR IEAGLEQQIV
LPQDSYLQGY FNNVSEYLRV GPPLYFVVKD YNYSAESSHT NKLCSISHCD ANSLLNEISR
ASLTPESSYI AKPAASWLDD FLVWLSPEAF GCCRKFINGT YCPPDDQPPC CTPDEGPCGI
GGVCEDCTTC FLQSDLKKGR PSTGQFREKL PWFLKALPSA DCAKGGHGAY TSSVNLNGYE
SGVIHASEFR TYHTPLNKQG DYVNSMRAAR EFSSRVSSSL KMDIFPYSVF YIFFEQYLDI
WRVALMNIAI ALGAIFVVFL VVTSSLWSSI IMLVVLAMIV VDLMGVMALL NIQLNAVSVV
NLVMSIGIAV EFCVHIMQAF LVCPGNRNQR MQGALTTMGA SVFSGITLTK LCGVLVLFFA
RSEIFVVYYF QMYLALVIIG FLHGLVLLPV LLSLFGPPPR YMVVEKQQHN TPASSQQS
//
