ID   A0A059BU54_EUCGR        Unreviewed;       890 AA.
AC   A0A059BU54;
DT   09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT   09-JUL-2014, sequence version 1.
DT   27-MAR-2024, entry version 43.
DE   RecName: Full=histidine--tRNA ligase {ECO:0000256|ARBA:ARBA00012815};
DE            EC=6.1.1.21 {ECO:0000256|ARBA:ARBA00012815};
GN   ORFNames=EUGRSUZ_F02946 {ECO:0000313|EMBL:KCW69499.1};
OS   Eucalyptus grandis (Flooded gum).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Myrtales; Myrtaceae; Myrtoideae; Eucalypteae; Eucalyptus.
OX   NCBI_TaxID=71139 {ECO:0000313|EMBL:KCW69499.1};
RN   [1] {ECO:0000313|EMBL:KCW69499.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Leaf extractions {ECO:0000313|EMBL:KCW69499.1};
RA   Schmutz J., Hayes R., Myburg A., Tuskan G., Grattapaglia D., Rokhsar D.S.;
RT   "The genome of Eucalyptus grandis.";
RL   Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + L-histidine + tRNA(His) = AMP + diphosphate + H(+) + L-
CC         histidyl-tRNA(His); Xref=Rhea:RHEA:17313, Rhea:RHEA-COMP:9665,
CC         Rhea:RHEA-COMP:9689, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:33019, ChEBI:CHEBI:57595, ChEBI:CHEBI:78442,
CC         ChEBI:CHEBI:78527, ChEBI:CHEBI:456215; EC=6.1.1.21;
CC         Evidence={ECO:0000256|ARBA:ARBA00001137};
CC   -!- SIMILARITY: Belongs to the class-II aminoacyl-tRNA synthetase family.
CC       {ECO:0000256|ARBA:ARBA00008226}.
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DR   EMBL; KK198758; KCW69499.1; -; Genomic_DNA.
DR   RefSeq; XP_010062368.1; XM_010064066.2.
DR   AlphaFoldDB; A0A059BU54; -.
DR   STRING; 71139.A0A059BU54; -.
DR   EnsemblPlants; KCW69499; KCW69499; EUGRSUZ_F02946.
DR   GeneID; 104449799; -.
DR   Gramene; KCW69499; KCW69499; EUGRSUZ_F02946.
DR   KEGG; egr:104449799; -.
DR   eggNOG; KOG1936; Eukaryota.
DR   InParanoid; A0A059BU54; -.
DR   OMA; IMEQQEM; -.
DR   OrthoDB; 5476704at2759; -.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0004821; F:histidine-tRNA ligase activity; IBA:GO_Central.
DR   GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR   GO; GO:0006427; P:histidyl-tRNA aminoacylation; IBA:GO_Central.
DR   GO; GO:0032543; P:mitochondrial translation; IBA:GO_Central.
DR   CDD; cd00773; HisRS-like_core; 1.
DR   Gene3D; 3.40.50.800; Anticodon-binding domain; 1.
DR   HAMAP; MF_00127; His_tRNA_synth; 1.
DR   InterPro; IPR006195; aa-tRNA-synth_II.
DR   InterPro; IPR045864; aa-tRNA-synth_II/BPL/LPL.
DR   InterPro; IPR004154; Anticodon-bd.
DR   InterPro; IPR036621; Anticodon-bd_dom_sf.
DR   InterPro; IPR015807; His-tRNA-ligase.
DR   InterPro; IPR041715; HisRS-like_core.
DR   NCBIfam; TIGR00442; hisS; 1.
DR   PANTHER; PTHR11476:SF7; HISTIDINE--TRNA LIGASE; 1.
DR   PANTHER; PTHR11476; HISTIDYL-TRNA SYNTHETASE; 1.
DR   Pfam; PF03129; HGTP_anticodon; 1.
DR   Pfam; PF13393; tRNA-synt_His; 1.
DR   SUPFAM; SSF52954; Class II aaRS ABD-related; 1.
DR   SUPFAM; SSF55681; Class II aaRS and biotin synthetases; 1.
DR   PROSITE; PS50862; AA_TRNA_LIGASE_II; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Ligase {ECO:0000256|ARBA:ARBA00022598};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT   DOMAIN          439..785
FT                   /note="Aminoacyl-transfer RNA synthetases class-II family
FT                   profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50862"
SQ   SEQUENCE   890 AA;  97205 MW;  C5BFF7BB92720D08 CRC64;
     MADGGETTAT ATATATATAT ALVALGGKGS SLSPSSLHAV SAGTARVRVD SSARDRLASS
     PPAANRTSPA AANLQISFPP YFTAAETRAS LAVLLNKLLV SGGPGTGTAL VDLISDSLNS
     AEGYEGFGNL AVTNEEVSIS EKAHSSLYGI SALLDHLSTA LSTTVDAVAA LSCEAIKADV
     AVFNPTDSGD GFVSKDEIGV ASDMKVLLNG SKLVGKVESE AISSILKVHA TLRRVVKSVH
     SEVRVYLNSS VKIQKTGSTT DGAAVVNVLW PLADVLLSIG ESSLCRAKMD LDAIAADALK
     SSLTGMFEKE CARMDDLENE KKVLNDAYVG REFEKFVHEL YVLCGCVWKT VVWEAITAFV
     ALEGSELIEK GKHEEINGVQ ADKKSEKKKK KVVLGRGTSV LVQLIKDRFQ RNGSDESVSL
     EKLVKDLLLF LDARGPEFDH FLNKVKDIVD SNESRRLPKL PKGTRDFGKE QMAVREKAFS
     IITEVFKKHG ATALDTPVFE LRETLMGKYG EDSKLIYDLA DQGGELCSLR YDLTVPFARY
     MAMNGLTSLK RYQIAKVYRR DNPSKGRYRE FYQCDLDIAG QNVRMGPDFE VIEVLVELLD
     KLNIGDYEIK LNHRKLLDGM LEICGVPAEK FRTICSSIDK LDKQSFDQIR KEMVEEKGLT
     AEVADRIGNF VKERGPPLEL LAKLQDTGSK FLENEGSVHA LKDLEILFNA LEKSKSINRV
     VFDLSLARGL DYYTGVIYEA VFKGATQVGT IAAGGRYDNL IGMFGTKQVP AVGVSLGIER
     VFAIMENQII RPTETQVLIG FLGDDLPLTA ELVKEFWVAG LKAEFLINKR VMKHIDYAKE
     YRIPWLVLVG ERELTEGVVK LKDFENAKEE VVPRSAIVQE LLSRLGAVRT
//