ID   A0A059C2H4_EUCGR        Unreviewed;       354 AA.
AC   A0A059C2H4;
DT   09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT   09-JUL-2014, sequence version 1.
DT   27-MAR-2024, entry version 37.
DE   RecName: Full=Enoyl reductase (ER) domain-containing protein {ECO:0000259|SMART:SM00829};
GN   ORFNames=EUGRSUZ_E01119 {ECO:0000313|EMBL:KCW72668.1};
OS   Eucalyptus grandis (Flooded gum).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Myrtales; Myrtaceae; Myrtoideae; Eucalypteae; Eucalyptus.
OX   NCBI_TaxID=71139 {ECO:0000313|EMBL:KCW72668.1};
RN   [1] {ECO:0000313|EMBL:KCW72668.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Leaf extractions {ECO:0000313|EMBL:KCW72668.1};
RA   Schmutz J., Hayes R., Myburg A., Tuskan G., Grattapaglia D., Rokhsar D.S.;
RT   "The genome of Eucalyptus grandis.";
RL   Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947,
CC         ECO:0000256|RuleBase:RU361277};
CC   -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC       family. {ECO:0000256|RuleBase:RU361277}.
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DR   EMBL; KK198757; KCW72665.1; -; Genomic_DNA.
DR   EMBL; KK198757; KCW72666.1; -; Genomic_DNA.
DR   EMBL; KK198757; KCW72667.1; -; Genomic_DNA.
DR   EMBL; KK198757; KCW72668.1; -; Genomic_DNA.
DR   RefSeq; XP_018729321.1; XM_018873776.1.
DR   RefSeq; XP_018729322.1; XM_018873777.1.
DR   RefSeq; XP_018729323.1; XM_018873778.1.
DR   RefSeq; XP_018729324.1; XM_018873779.1.
DR   RefSeq; XP_018729325.1; XM_018873780.1.
DR   RefSeq; XP_018729326.1; XM_018873781.1.
DR   RefSeq; XP_018729327.1; XM_018873782.1.
DR   RefSeq; XP_018729328.1; XM_018873783.1.
DR   RefSeq; XP_018729329.1; XM_018873784.1.
DR   RefSeq; XP_018729330.1; XM_018873785.1.
DR   RefSeq; XP_018729331.1; XM_018873786.1.
DR   RefSeq; XP_018729332.1; XM_018873787.1.
DR   RefSeq; XP_018729333.1; XM_018873788.1.
DR   EnsemblPlants; KCW72665; KCW72665; EUGRSUZ_E01119.
DR   EnsemblPlants; KCW72666; KCW72666; EUGRSUZ_E01119.
DR   EnsemblPlants; KCW72667; KCW72667; EUGRSUZ_E01119.
DR   EnsemblPlants; KCW72668; KCW72668; EUGRSUZ_E01119.
DR   GeneID; 104444157; -.
DR   Gramene; KCW72665; KCW72665; EUGRSUZ_E01119.
DR   Gramene; KCW72666; KCW72666; EUGRSUZ_E01119.
DR   Gramene; KCW72667; KCW72667; EUGRSUZ_E01119.
DR   Gramene; KCW72668; KCW72668; EUGRSUZ_E01119.
DR   OrthoDB; 1550at2759; -.
DR   GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0009809; P:lignin biosynthetic process; IEA:UniProt.
DR   CDD; cd05283; CAD1; 1.
DR   Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR013149; ADH-like_C.
DR   InterPro; IPR013154; ADH-like_N.
DR   InterPro; IPR002328; ADH_Zn_CS.
DR   InterPro; IPR047109; CAD-like.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020843; PKS_ER.
DR   PANTHER; PTHR42683; ALDEHYDE REDUCTASE; 1.
DR   PANTHER; PTHR42683:SF17; CINNAMYL ALCOHOL DEHYDROGENASE 1-RELATED; 1.
DR   Pfam; PF08240; ADH_N; 1.
DR   Pfam; PF00107; ADH_zinc_N; 1.
DR   SMART; SM00829; PKS_ER; 1.
DR   SUPFAM; SSF50129; GroES-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   PROSITE; PS00059; ADH_ZINC; 1.
PE   3: Inferred from homology;
KW   Metal-binding {ECO:0000256|RuleBase:RU361277};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Zinc {ECO:0000256|RuleBase:RU361277}.
FT   DOMAIN          20..347
FT                   /note="Enoyl reductase (ER)"
FT                   /evidence="ECO:0000259|SMART:SM00829"
SQ   SEQUENCE   354 AA;  38536 MW;  574BCDDC1C027B51 CRC64;
     MSSEGGKEDC LGWAARDPSG FLSPYKFTRR AVGSEDVSIK ITHCGVCYAD VAWTRNVQGH
     SKYPLVPGHE IVGIVKQVGS SVQRFKVGDH VGVGTYVNSC RECEYCNDRL EVQCEKAVLT
     FDGIDADGTV TKGGYSSHIV VHERYCFRIP ENYPMDLAAP LLCAGITVYT PMIRHKMNQP
     GKSLGVIGLG GLGHMAVKFG KAFGLKVTVL STSISKKEEA LSLLGADHFV ISSDVEQMKA
     IAKSLDFIID TAAGDHPFDP YMSLLKTGGI LALVGFPSEV KFSPASLNLN MRTVTGSVTG
     GTKDTQEMID LCAAQKIYPN IEVIPIDYAN EALERLIKRD VKYRFVIDIE NSLK
//