ID A0A059C3S2_EUCGR Unreviewed; 336 AA.
AC A0A059C3S2;
DT 09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT 09-JUL-2014, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=EUGRSUZ_E01337 {ECO:0000313|EMBL:KCW72894.1};
OS Eucalyptus grandis (Flooded gum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Myrtales; Myrtaceae; Myrtoideae; Eucalypteae; Eucalyptus.
OX NCBI_TaxID=71139 {ECO:0000313|EMBL:KCW72894.1};
RN [1] {ECO:0000313|EMBL:KCW72894.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf extractions {ECO:0000313|EMBL:KCW72894.1};
RA Schmutz J., Hayes R., Myburg A., Tuskan G., Grattapaglia D., Rokhsar D.S.;
RT "The genome of Eucalyptus grandis.";
RL Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the D-isomer specific 2-hydroxyacid
CC dehydrogenase family. {ECO:0000256|RuleBase:RU003719}.
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DR EMBL; KK198757; KCW72893.1; -; Genomic_DNA.
DR EMBL; KK198757; KCW72894.1; -; Genomic_DNA.
DR RefSeq; XP_010056258.1; XM_010057956.2.
DR EnsemblPlants; KCW72893; KCW72893; EUGRSUZ_E01337.
DR EnsemblPlants; KCW72894; KCW72894; EUGRSUZ_E01337.
DR GeneID; 104444300; -.
DR Gramene; KCW72893; KCW72893; EUGRSUZ_E01337.
DR Gramene; KCW72894; KCW72894; EUGRSUZ_E01337.
DR KEGG; egr:104444300; -.
DR eggNOG; KOG0069; Eukaryota.
DR OrthoDB; 1327616at2759; -.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR CDD; cd12156; HPPR; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR006139; D-isomer_2_OHA_DH_cat_dom.
DR InterPro; IPR006140; D-isomer_DH_NAD-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR10996; 2-HYDROXYACID DEHYDROGENASE-RELATED; 1.
DR PANTHER; PTHR10996:SF179; D-ISOMER SPECIFIC 2-HYDROXYACID DEHYDROGENASE FAMILY PROTEIN-RELATED; 1.
DR Pfam; PF00389; 2-Hacid_dh; 1.
DR Pfam; PF02826; 2-Hacid_dh_C; 1.
DR SUPFAM; SSF52283; Formate/glycerate dehydrogenase catalytic domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|RuleBase:RU003719}.
FT DOMAIN 61..333
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase
FT catalytic"
FT /evidence="ECO:0000259|Pfam:PF00389"
FT DOMAIN 129..302
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase NAD-
FT binding"
FT /evidence="ECO:0000259|Pfam:PF02826"
SQ SEQUENCE 336 AA; 36430 MW; 18DAA2C2FFF462DA CRC64;
MAADPESSGG PPPLRRRAPP CVLLLRHPPH FTLIDRPLPD GFRFLKPWES PLPFDDFLAS
DDVRSAEAIL TSQGVPVTAD MLRRLPAVRL VLTTSAGLNH IDLAECRRRG VAVAGAGEVY
SEEVADLAIG LLIDVLRKVS AGDRYVRRGS WSGEGEFALG SKLGGKRAGV VGLGRIGLEV
AKRLEAFGCT VSYNSRKKKP YVLYPFYSDV RELATNCDVL VICCGLNEQT HHMINREVLL
ALGKEGVIVN IGRGSIIDEK EMVQLLVQGE LGGAGLDVFE NEPKVPEELL ALDNVVLSPH
TAVFTTESLS ELCNLVVGNL EAFFSDKPLL SPVLDE
//
