ID   A0A059C8G2_EUCGR        Unreviewed;       526 AA.
AC   A0A059C8G2;
DT   09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT   09-JUL-2014, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   RecName: Full=MLO-like protein {ECO:0000256|RuleBase:RU280816};
GN   Name=MLO {ECO:0000256|RuleBase:RU280816};
GN   ORFNames=EUGRSUZ_E03224 {ECO:0000313|EMBL:KCW74509.1};
OS   Eucalyptus grandis (Flooded gum).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Myrtales; Myrtaceae; Myrtoideae; Eucalypteae; Eucalyptus.
OX   NCBI_TaxID=71139 {ECO:0000313|EMBL:KCW74509.1};
RN   [1] {ECO:0000313|EMBL:KCW74509.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Leaf extractions {ECO:0000313|EMBL:KCW74509.1};
RA   Schmutz J., Hayes R., Myburg A., Tuskan G., Grattapaglia D., Rokhsar D.S.;
RT   "The genome of Eucalyptus grandis.";
RL   Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May be involved in modulation of pathogen defense and leaf
CC       cell death. {ECO:0000256|RuleBase:RU280816}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU280816}; Multi-
CC       pass membrane protein {ECO:0000256|RuleBase:RU280816}.
CC   -!- DOMAIN: The C-terminus contains a calmodulin-binding domain, which
CC       binds calmodulin in a calcium-dependent fashion.
CC       {ECO:0000256|RuleBase:RU280816}.
CC   -!- SIMILARITY: Belongs to the MLO family. {ECO:0000256|ARBA:ARBA00006574,
CC       ECO:0000256|RuleBase:RU280816}.
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DR   EMBL; KK198757; KCW74509.1; -; Genomic_DNA.
DR   RefSeq; XP_010057357.1; XM_010059055.2.
DR   AlphaFoldDB; A0A059C8G2; -.
DR   EnsemblPlants; KCW74509; KCW74509; EUGRSUZ_E03224.
DR   GeneID; 104445233; -.
DR   Gramene; KCW74509; KCW74509; EUGRSUZ_E03224.
DR   KEGG; egr:104445233; -.
DR   eggNOG; ENOG502QQFC; Eukaryota.
DR   InParanoid; A0A059C8G2; -.
DR   OMA; SWWIWIF; -.
DR   OrthoDB; 368831at2759; -.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
DR   GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR   GO; GO:0009607; P:response to biotic stimulus; IEA:UniProtKB-KW.
DR   InterPro; IPR004326; Mlo.
DR   PANTHER; PTHR31942:SF72; MLO-LIKE PROTEIN; 1.
DR   PANTHER; PTHR31942; MLO-LIKE PROTEIN 1; 1.
DR   Pfam; PF03094; Mlo; 2.
PE   3: Inferred from homology;
KW   Calmodulin-binding {ECO:0000256|RuleBase:RU280816};
KW   Membrane {ECO:0000256|RuleBase:RU280816, ECO:0000256|SAM:Phobius};
KW   Pathogenesis-related protein {ECO:0000256|ARBA:ARBA00023265,
KW   ECO:0000256|RuleBase:RU280816};
KW   Plant defense {ECO:0000256|RuleBase:RU280816};
KW   Transmembrane {ECO:0000256|RuleBase:RU280816, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU280816,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        20..44
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        65..84
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        130..151
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        253..272
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        278..296
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        337..360
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        380..401
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   526 AA;  60535 MW;  69AA04842245519E CRC64;
     MSETSAESVE ELTLESTPTW AVATVCFVLI LVSVFLEHLI HLLAQYLQNK KKRSLIQALD
     KIKSELMLLG FISLLLTVTE RWIANICIPK SVAETFLPCS TWESSEEEEE TKCLEQGKVS
     LLSREGVRQL QYLIFVLAFF HSLSCMLTFA LGMAKMRKWE SWEAETRTLD YQFSNDPRRF
     KLVHQTSFAR RHLTCWSDLR ILRWPGCFLR QFYNSVSKVD YMTLRHGFIM AHLSEGSTFD
     FQKYIERALE KDFGVVVGIS FWIWIFLVIF IFFHAHVFYN YLWLPFIPLV MLLLVGTKLQ
     GIITKMCIDS NDKSNVVRGT LLVRPSDHFF WFGRPKLLLH LMHFILFQNS FQVAFFTWTW
     YKFGFRSCFH ERTEDIIIEF TMGALVQFLC GYVTLPLYAL VTQMGTSMSG AVFTENVREG
     LKRWRATARK NLAPRDPYAA CLSLEASVTS LDASVTSLDA SVTSHDAYSP SFGHDAAFSI
     DLDHPDLESS ISLDTVDGEN NSHLKTVEDR RKKGSFDGFV ISSTTR
//