ID   A0A059C954_EUCGR        Unreviewed;      1165 AA.
AC   A0A059C954;
DT   09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT   09-JUL-2014, sequence version 1.
DT   27-MAR-2024, entry version 33.
DE   RecName: Full=TIR domain-containing protein {ECO:0000259|PROSITE:PS50104};
GN   ORFNames=EUGRSUZ_E03133 {ECO:0000313|EMBL:KCW74435.1};
OS   Eucalyptus grandis (Flooded gum).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Myrtales; Myrtaceae; Myrtoideae; Eucalypteae; Eucalyptus.
OX   NCBI_TaxID=71139 {ECO:0000313|EMBL:KCW74435.1};
RN   [1] {ECO:0000313|EMBL:KCW74435.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Leaf extractions {ECO:0000313|EMBL:KCW74435.1};
RA   Schmutz J., Hayes R., Myburg A., Tuskan G., Grattapaglia D., Rokhsar D.S.;
RT   "The genome of Eucalyptus grandis.";
RL   Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KK198757; KCW74435.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A059C954; -.
DR   EnsemblPlants; KCW74435; KCW74435; EUGRSUZ_E03133.
DR   Gramene; KCW74435; KCW74435; EUGRSUZ_E03133.
DR   InParanoid; A0A059C954; -.
DR   GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR   GO; GO:0006952; P:defense response; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 3.
DR   Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR   InterPro; IPR042197; Apaf_helical.
DR   InterPro; IPR044974; Disease_R_plants.
DR   InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR002182; NB-ARC.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR000157; TIR_dom.
DR   InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR11017:SF580; DISEASE RESISTANCE-LIKE PROTEIN DSC1; 1.
DR   PANTHER; PTHR11017; LEUCINE-RICH REPEAT-CONTAINING PROTEIN; 1.
DR   Pfam; PF00931; NB-ARC; 1.
DR   Pfam; PF01582; TIR; 1.
DR   PRINTS; PR00364; DISEASERSIST.
DR   SMART; SM00369; LRR_TYP; 4.
DR   SMART; SM00255; TIR; 1.
DR   SUPFAM; SSF52058; L domain-like; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF52047; RNI-like; 1.
DR   SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS50104; TIR; 1.
PE   4: Predicted;
KW   Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          63..201
FT                   /note="TIR"
FT                   /evidence="ECO:0000259|PROSITE:PS50104"
SQ   SEQUENCE   1165 AA;  131171 MW;  DBEE18A978CE5968 CRC64;
     MEWNTVKLAV LFLFFGSVLS LPLQILLVMT LGAIAITASL TRRTMTTDSH SSSSAPISDL
     AGNNYDVFLS FRGPDTRRSF TDILHQRLTD AEIHVFLDDN ELPFGEPIKP ELIKAIKQSE
     VLIPIISADY ASSRSCLMEL VEMLECKQRM SREIIPIFYE IDPSDLKEQK NSFAESFREH
     RRNGVNGKTI EEWKLALKQI GSLRGFETEK IHNGLHSKIM DKLIPVVLQT LKKGLLPMEE
     YMVGVDHHVQ KIMRKLGVVH HYGEVFELCR SGVQVLGIYG IGGVGKSTIA KFVYNQLYGH
     FQGYSYVDIP KLCQDDLTLS LQNKLISDLR KRTAQFTCSN DARTALAKRF QNEQVLILLD
     GMDNVGPLNS VVQKLTWFGQ GSRIIVTSRK SNILQGFKEA ETYEVEAMEE DKALQLFSKL
     AFGRDCPDKG FESLSKNITE ATGRVPLALE VTGKFLSGKP KDIWKETLDQ LKDAPHEKVK
     TVLKISYNAL ADNAKQIFLD IACFLIGKGS RIAFYMWEDC KLCPHTEIDA LRVQSLVKIG
     ENDELLMHDL LRTLGRSLVK NEDPVPRNRS RLWMHNQALS ILQRTEGTPT VQALGLAFDK
     GSDDCFTSRE FDQLSQLRFL DLDRANMRGN FTGLLSQLRW LRWQGYHKSS EPLIFCLENL
     VILDLSWSAV ADDWEGWTQI IEKANKLKVL DLSGCSQLRK TPCFPAEGKL ERLILEGCSQ
     LSLIDKSIGK LKYLKSLNIK STPIVLFPKE MGSLDNLEEL LIDKTSIRHL HFLKGSMEHL
     KTLSASGCKS LAEISKSIGY VRSLSYLALD EANIPGLPDS VTLLKGLEEL SLRDCQQMTA
     LPVSIEMLTS LQKLDLSNTK IKILPKSIKY LVKLQVLRME KTHISKFPDD ITNLGTLQFI
     TFSDCQSLNG KIMCDISGLS SLRSLDLSYT RICSLPESIY ALPHLQTLHL LGCDKLQTLP
     SLPSSLVSLR WGTKNMRIVL DFSNLTDLKV LELVNVPDEE DIPFSEPSQT ENFGWISSLS
     NLETLKLCLP NVTSLPEYFD ALTRLKTLDL SCINLLDLPQ LPSSLSKLLL KNCKSQRVDF
     SNLEILSGLE LCDCNASEIL GLGNLRLLQV LKISGCNMKN LDGLEQSSQL RWFSMSECLS
     LDRLPDLSRC ASLKFKEIVF CNIQD
//