ID   A0A059CI64_EUCGR        Unreviewed;       645 AA.
AC   A0A059CI64;
DT   09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT   09-JUL-2014, sequence version 1.
DT   27-MAR-2024, entry version 32.
DE   RecName: Full=SPX domain-containing protein {ECO:0000259|PROSITE:PS51382};
GN   ORFNames=EUGRSUZ_D01930 {ECO:0000313|EMBL:KCW77620.1};
OS   Eucalyptus grandis (Flooded gum).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Myrtales; Myrtaceae; Myrtoideae; Eucalypteae; Eucalyptus.
OX   NCBI_TaxID=71139 {ECO:0000313|EMBL:KCW77620.1};
RN   [1] {ECO:0000313|EMBL:KCW77620.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Leaf extractions {ECO:0000313|EMBL:KCW77620.1};
RA   Schmutz J., Hayes R., Myburg A., Tuskan G., Grattapaglia D., Rokhsar D.S.;
RT   "The genome of Eucalyptus grandis.";
RL   Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily.
CC       {ECO:0000256|ARBA:ARBA00008335}.
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DR   EMBL; KK198756; KCW77620.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A059CI64; -.
DR   EnsemblPlants; KCW77620; KCW77620; EUGRSUZ_D01930.
DR   Gramene; KCW77620; KCW77620; EUGRSUZ_D01930.
DR   eggNOG; KOG1161; Eukaryota.
DR   eggNOG; KOG2325; Eukaryota.
DR   InParanoid; A0A059CI64; -.
DR   OMA; QAYYINY; -.
DR   GO; GO:0009705; C:plant-type vacuole membrane; IBA:GO_Central.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:1905011; P:transmembrane phosphate ion transport from cytosol to vacuole; IBA:GO_Central.
DR   CDD; cd14479; SPX-MFS_plant; 1.
DR   Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   InterPro; IPR004331; SPX_dom.
DR   InterPro; IPR045264; SPXM_SPX_plant.
DR   PANTHER; PTHR23510; INNER MEMBRANE TRANSPORT PROTEIN YAJR; 1.
DR   PANTHER; PTHR23510:SF75; SPX DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF07690; MFS_1; 1.
DR   Pfam; PF03105; SPX; 1.
DR   SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR   PROSITE; PS51382; SPX; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        197..215
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        221..250
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        262..279
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        285..303
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        324..346
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        358..378
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        461..487
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        493..512
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        524..544
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        550..573
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        623..644
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          1..92
FT                   /note="SPX"
FT                   /evidence="ECO:0000259|PROSITE:PS51382"
SQ   SEQUENCE   645 AA;  71697 MW;  0630957F3ECC94A9 CRC64;
     MLDNQIEKIV LFLLEQQGLL ASRIAKLGEQ QEALQEHPDI SQISELREAY RTVGRDLLKL
     LYFVEINAIG LRKILKKFDK RFGYRFTDYY IKTRANHPYS QLQQVFKHVG IGAVVGAISR
     NLGELQDRQG SYISIYDQPP LPLQDSVIDL MKAAVDRLTH STNFLNFLAQ HALILQEELP
     FPVDEHVEDQ RYHFMSLMLN LASTFLYMVN TYIIVPTADD YALSLGAAAT VCGIVIGAMA
     VAQIFSSVYF SAWSNKSYFR PLIFSTIVLF VGNVMYALAY DLDSIVVLLV GRLFCGLGSA
     RAVNRRYISD CVPLKIRMQA SAGFVSASAL GMACGPALAG LLQYNFKIYK LTFNEETLPG
     WVMAVAWLIY LIWLWILFKE PSREVEANET PQESNAEPVE GDALENGIKK PLLISSERME
     QDADGDNECE GSDEAPEESH QAATSLQSAY RLLTPSVKVQ LLIYFMLKYA MEILLSESSV
     ITTYYFGWST SSVAIFLACL GLTVLPVNIV VGNYICNMFE DRQILLASEI VVCIGILLSF
     HVFIPYSIPQ YVISGLIMFV SAEVLEGVNL SLLSRVMSSR LSRGTYNGGL LSTEAGTIAR
     VVADSTITLA GYLGDSKLLN VTLLPSLIIC ISSIIATLCT YNSLY
//