ID   A0A059CRE0_EUCGR        Unreviewed;       409 AA.
AC   A0A059CRE0;
DT   09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT   09-JUL-2014, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   RecName: Full=Protein DETOXIFICATION {ECO:0008006|Google:ProtNLM};
GN   ORFNames=EUGRSUZ_C02409 {ECO:0000313|EMBL:KCW81033.1};
OS   Eucalyptus grandis (Flooded gum).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Myrtales; Myrtaceae; Myrtoideae; Eucalypteae; Eucalyptus.
OX   NCBI_TaxID=71139 {ECO:0000313|EMBL:KCW81033.1};
RN   [1] {ECO:0000313|EMBL:KCW81033.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Leaf extractions {ECO:0000313|EMBL:KCW81033.1};
RA   Schmutz J., Hayes R., Myburg A., Tuskan G., Grattapaglia D., Rokhsar D.S.;
RT   "The genome of Eucalyptus grandis.";
RL   Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the multi antimicrobial extrusion (MATE) (TC
CC       2.A.66.1) family. {ECO:0000256|ARBA:ARBA00010199}.
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DR   EMBL; KK198755; KCW81033.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A059CRE0; -.
DR   EnsemblPlants; KCW81033; KCW81033; EUGRSUZ_C02409.
DR   Gramene; KCW81033; KCW81033; EUGRSUZ_C02409.
DR   eggNOG; KOG1347; Eukaryota.
DR   InParanoid; A0A059CRE0; -.
DR   OMA; LECPLIS; -.
DR   GO; GO:0016020; C:membrane; IBA:GO_Central.
DR   GO; GO:0015297; F:antiporter activity; IEA:InterPro.
DR   GO; GO:0022857; F:transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0042910; F:xenobiotic transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:1990961; P:xenobiotic detoxification by transmembrane export across the plasma membrane; IEA:InterPro.
DR   CDD; cd13132; MATE_eukaryotic; 1.
DR   InterPro; IPR045069; MATE_euk.
DR   InterPro; IPR002528; MATE_fam.
DR   NCBIfam; TIGR00797; matE; 1.
DR   PANTHER; PTHR11206; MULTIDRUG RESISTANCE PROTEIN; 1.
DR   PANTHER; PTHR11206:SF196; PROTEIN DETOXIFICATION; 1.
DR   Pfam; PF01554; MatE; 2.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        124..147
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        159..178
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        190..209
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        221..240
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        261..280
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        300..318
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        339..361
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   409 AA;  45114 MW;  BA58FA72EE34310B CRC64;
     MDVEEQKQHL ESLLLAVPRE KAASTLGNGF KKDEIFSEIK QQLSLAGPLV SVNLMIYCLQ
     VISVMFVGHL GELALSGASM ATSFASVTGF SMLEWQVHWD TFCGQSYGAK QYHMLGIHKQ
     RAMIVLLLAS IPLAIIWANT GQILLFFKQD PQISAEAGSY ARFMIPSIFA YALLQCHVRF
     LQTQNNVVPM MVSSGITTFL HIFICWFLVF KSGLGNKGAA LANAISYWIN VLLLAIYVRI
     SPSCKRTWTG FSKEAFHGIP EFLKLAIPSA VMICFEIWSF EMMVLLSGLL PNPKLETSVL
     SISLNTCSLV YMIPLGLSGS ISTRVSNELG AGRPRAARLA IYVSLMMVAT EGLLAGTLMI
     FCRRAWGYLY STEEEIVNYV GDMLVLIATS NLIDGIQSVL SGMHQVCLF
//