ID   A0A059CVG1_EUCGR        Unreviewed;       623 AA.
AC   A0A059CVG1;
DT   09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT   09-JUL-2014, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   RecName: Full=Mechanosensitive ion channel MscS domain-containing protein {ECO:0000259|Pfam:PF00924};
GN   ORFNames=EUGRSUZ_C03566 {ECO:0000313|EMBL:KCW82176.1};
OS   Eucalyptus grandis (Flooded gum).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Myrtales; Myrtaceae; Myrtoideae; Eucalypteae; Eucalyptus.
OX   NCBI_TaxID=71139 {ECO:0000313|EMBL:KCW82176.1};
RN   [1] {ECO:0000313|EMBL:KCW82176.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Leaf extractions {ECO:0000313|EMBL:KCW82176.1};
RA   Schmutz J., Hayes R., Myburg A., Tuskan G., Grattapaglia D., Rokhsar D.S.;
RT   "The genome of Eucalyptus grandis.";
RL   Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; KK198755; KCW82176.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A059CVG1; -.
DR   STRING; 71139.A0A059CVG1; -.
DR   EnsemblPlants; KCW82176; KCW82176; EUGRSUZ_C03566.
DR   Gramene; KCW82176; KCW82176; EUGRSUZ_C03566.
DR   eggNOG; KOG4629; Eukaryota.
DR   InParanoid; A0A059CVG1; -.
DR   OMA; WNIEHEE; -.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0008381; F:mechanosensitive monoatomic ion channel activity; IBA:GO_Central.
DR   GO; GO:0050982; P:detection of mechanical stimulus; IBA:GO_Central.
DR   GO; GO:0006820; P:monoatomic anion transport; IBA:GO_Central.
DR   Gene3D; 2.30.30.60; -; 1.
DR   InterPro; IPR010920; LSM_dom_sf.
DR   InterPro; IPR016688; MscS-like_plants/fungi.
DR   InterPro; IPR023408; MscS_beta-dom_sf.
DR   InterPro; IPR006685; MscS_channel_2nd.
DR   PANTHER; PTHR31618:SF7; MECHANOSENSITIVE ION CHANNEL PROTEIN; 1.
DR   PANTHER; PTHR31618; MECHANOSENSITIVE ION CHANNEL PROTEIN 5; 1.
DR   Pfam; PF00924; MS_channel_2nd; 1.
DR   SUPFAM; SSF50182; Sm-like ribonucleoproteins; 1.
PE   4: Predicted;
KW   Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW   Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00023065}.
FT   TRANSMEM        152..173
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        179..197
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        218..235
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        255..280
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        416..436
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          459..523
FT                   /note="Mechanosensitive ion channel MscS"
FT                   /evidence="ECO:0000259|Pfam:PF00924"
FT   REGION          25..105
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        28..105
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   623 AA;  70408 MW;  14242D2AA63E59EE CRC64;
     MEVNASPLEK KEANEVVLRI SGVECQIRGS SPKPNTEPIE LENPLSSSQI SNSTSPSAME
     LTQSIPTPSE LLNIQTRKSI SSSTNEKLKS RSMEPPHPSD TSASASKGAV ELALSKFPVS
     SVPSPAVEDE DDEDVCETVN PESQVMSGRM KFILAQLVMF VCITVLLIAS LTIRNLRNIV
     IWHLATDWSI ALLVFLIDKK YLPEKKVFYF LFASKNSAAV FAWLCLVILA WVLLINHGVK
     CSRHTTKILN RVTRALLSCL IGAALWLIKS VLITSLAVSF QHKRIFDRMQ DYFFQHYVIR
     QLSGPVVPSL KVDIEKLIKM KLDKVFPRKI INLADSLRDK EMTNGQEAKD AAKKIFKNVA
     KSGSQFIEKD DLLRFMPKER VEKFLAFFPG AKETGKIRKS LFKIWLKTCI DKLDKLASAL
     FLVVIIILGL LLTGLLTTPV QIFISSQLLL LEFIFGNAAK DLFEAIVFVF VKHPFDVSDR
     CLVDGDELEV EEMNIMTTVF LTKDDEKKSY PNSVLASKPI INSGRSAKMS ESLEFVVDLS
     TSVESLEALT NKIREYIERK PRHWHRDHSV EFKEIAEVDN SKVLKMALHV THTLDCQEVM
     ERTKRRSELV LELKKIFEEL HLK
//