ID A0A059CXA4_EUCGR Unreviewed; 493 AA.
AC A0A059CXA4;
DT 09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT 09-JUL-2014, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=Protein DETOXIFICATION {ECO:0000256|RuleBase:RU004914};
DE AltName: Full=Multidrug and toxic compound extrusion protein {ECO:0000256|RuleBase:RU004914};
GN ORFNames=EUGRSUZ_B00058 {ECO:0000313|EMBL:KCW83103.1};
OS Eucalyptus grandis (Flooded gum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Myrtales; Myrtaceae; Myrtoideae; Eucalypteae; Eucalyptus.
OX NCBI_TaxID=71139 {ECO:0000313|EMBL:KCW83103.1};
RN [1] {ECO:0000313|EMBL:KCW83103.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf extractions {ECO:0000313|EMBL:KCW83103.1};
RA Schmutz J., Hayes R., Myburg A., Tuskan G., Grattapaglia D., Rokhsar D.S.;
RT "The genome of Eucalyptus grandis.";
RL Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the multi antimicrobial extrusion (MATE) (TC
CC 2.A.66.1) family. {ECO:0000256|ARBA:ARBA00010199,
CC ECO:0000256|RuleBase:RU004914}.
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DR EMBL; KK198754; KCW83103.1; -; Genomic_DNA.
DR RefSeq; XP_010026120.1; XM_010027818.2.
DR AlphaFoldDB; A0A059CXA4; -.
DR EnsemblPlants; KCW83103; KCW83103; EUGRSUZ_B00058.
DR GeneID; 104416416; -.
DR Gramene; KCW83103; KCW83103; EUGRSUZ_B00058.
DR KEGG; egr:104416416; -.
DR eggNOG; KOG1347; Eukaryota.
DR InParanoid; A0A059CXA4; -.
DR OMA; AINIVWP; -.
DR OrthoDB; 10858at2759; -.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0015297; F:antiporter activity; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0042910; F:xenobiotic transmembrane transporter activity; IEA:InterPro.
DR GO; GO:1990961; P:xenobiotic detoxification by transmembrane export across the plasma membrane; IEA:InterPro.
DR CDD; cd13132; MATE_eukaryotic; 1.
DR InterPro; IPR045069; MATE_euk.
DR InterPro; IPR002528; MATE_fam.
DR NCBIfam; TIGR00797; matE; 1.
DR PANTHER; PTHR11206; MULTIDRUG RESISTANCE PROTEIN; 1.
DR PANTHER; PTHR11206:SF130; PROTEIN DETOXIFICATION; 1.
DR Pfam; PF01554; MatE; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|RuleBase:RU004914};
KW Transmembrane {ECO:0000256|RuleBase:RU004914};
KW Transmembrane helix {ECO:0000256|RuleBase:RU004914}.
FT TRANSMEM 55..75
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004914"
FT TRANSMEM 81..108
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004914"
FT TRANSMEM 129..150
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004914"
FT TRANSMEM 162..183
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004914"
FT TRANSMEM 195..216
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004914"
FT TRANSMEM 231..253
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004914"
FT TRANSMEM 260..280
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004914"
FT TRANSMEM 300..323
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004914"
FT TRANSMEM 344..367
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004914"
FT TRANSMEM 373..398
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004914"
FT TRANSMEM 419..441
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004914"
FT TRANSMEM 447..468
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004914"
FT REGION 1..31
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 15..31
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 493 AA; 53316 MW; A6C35B482D4DAE78 CRC64;
MGTTERGEQN PLLASPSHDE DERREEKEDD PVQLGLLSRT LSESKELWRV AGPSIFSRVA
LYSITVVTQA FAGHLGDIDL AAISIATTVI ISISFGFLLG MASALETLCG QAYGAKQYRM
LGIYLQRSWI VLFACSILLL PLFVFATPIL KLIGQSSAVA EQTGVVAIWL IPFHLCFPFQ
FTLQRFLQSQ LKTAVIVWVS GGSLALHMLI SWLFVYKLRV GLVGTALTID FSWWVTVLGM
FGYTVYGGCP LTWTGFSTQA IVGLGEFLKL SIASGVMLLL ENFYYRVLII VSGYLNNSEV
AVDALSICIT MFGWESMIAL GFLAATGVRV ANELGAGNAK GAKFALLVSL FSSLVVGILF
CTIVIAFNKK LAMIFSSSVA IINMVNELAV LLAFTILFNS IQPVLSGAAV GSGWQALAAV
VNIGSYYLIG VPLGVLFGWF LSFGITGTWA GMISGTVVQT LILALITVKC EWEEEARKAK
TRVRNEAGLI GDI
//
