ID A0A059CY50_EUCGR Unreviewed; 502 AA.
AC A0A059CY50;
DT 09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT 09-JUL-2014, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=Protein DETOXIFICATION {ECO:0000256|RuleBase:RU004914};
DE AltName: Full=Multidrug and toxic compound extrusion protein {ECO:0000256|RuleBase:RU004914};
GN ORFNames=EUGRSUZ_B00055 {ECO:0000313|EMBL:KCW83096.1};
OS Eucalyptus grandis (Flooded gum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Myrtales; Myrtaceae; Myrtoideae; Eucalypteae; Eucalyptus.
OX NCBI_TaxID=71139 {ECO:0000313|EMBL:KCW83096.1};
RN [1] {ECO:0000313|EMBL:KCW83096.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf extractions {ECO:0000313|EMBL:KCW83096.1};
RA Schmutz J., Hayes R., Myburg A., Tuskan G., Grattapaglia D., Rokhsar D.S.;
RT "The genome of Eucalyptus grandis.";
RL Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the multi antimicrobial extrusion (MATE) (TC
CC 2.A.66.1) family. {ECO:0000256|ARBA:ARBA00010199,
CC ECO:0000256|RuleBase:RU004914}.
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DR EMBL; KK198754; KCW83096.1; -; Genomic_DNA.
DR RefSeq; XP_010045479.1; XM_010047177.2.
DR RefSeq; XP_018721447.1; XM_018865902.1.
DR AlphaFoldDB; A0A059CY50; -.
DR EnsemblPlants; KCW83096; KCW83096; EUGRSUZ_B00055.
DR GeneID; 104434201; -.
DR Gramene; KCW83096; KCW83096; EUGRSUZ_B00055.
DR KEGG; egr:104434201; -.
DR eggNOG; KOG1347; Eukaryota.
DR InParanoid; A0A059CY50; -.
DR OMA; DVAEWSG; -.
DR OrthoDB; 10858at2759; -.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0015297; F:antiporter activity; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0042910; F:xenobiotic transmembrane transporter activity; IEA:InterPro.
DR GO; GO:1990961; P:xenobiotic detoxification by transmembrane export across the plasma membrane; IEA:InterPro.
DR CDD; cd13132; MATE_eukaryotic; 1.
DR InterPro; IPR045069; MATE_euk.
DR InterPro; IPR002528; MATE_fam.
DR NCBIfam; TIGR00797; matE; 1.
DR PANTHER; PTHR11206; MULTIDRUG RESISTANCE PROTEIN; 1.
DR PANTHER; PTHR11206:SF194; PROTEIN DETOXIFICATION; 1.
DR Pfam; PF01554; MatE; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|RuleBase:RU004914};
KW Transmembrane {ECO:0000256|RuleBase:RU004914};
KW Transmembrane helix {ECO:0000256|RuleBase:RU004914}.
FT TRANSMEM 87..110
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004914"
FT TRANSMEM 131..148
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004914"
FT TRANSMEM 168..185
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004914"
FT TRANSMEM 197..220
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004914"
FT TRANSMEM 235..257
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004914"
FT TRANSMEM 269..287
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004914"
FT TRANSMEM 318..334
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004914"
FT TRANSMEM 346..370
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004914"
FT TRANSMEM 390..412
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004914"
FT TRANSMEM 419..443
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004914"
FT TRANSMEM 449..471
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004914"
SQ SEQUENCE 502 AA; 54905 MW; CF2B05E63032DC2D CRC64;
MAIVDRDGSD AQWPLLRESA VDGDRNGGDH ENEEEKSLSV RVWAETKKLW HIVGPAIFSR
VASYTMNVVT QAFAGHLGEV ELAAMSIANT VIVGFNFGLL LGMASALETL CGQAFGAKRY
HMLGIYMQRS WIVLFLCCFL LLPFYVFATP LLRLLGQPDD VAEMSGTVAL WLIPLHFSFA
FQFPLTRFLQ SQLKTQVLAW VSLAGLAINV LTSWLCVYVF DFGVVGLSVG LDLSWWFLVL
ALFAYTACGN CPLTWTGLSM EAFTGLWEFV KLSAASGVML CLENWYYRIL ILMTGYLQNA
TVAVDALSVC MTINGWEMMI PLAFFAATGV RVANELGAGN GMAAKFATAV SVVQSTIIGF
FFCALIMVLH DKFAYIFTSS ADVLEEVDTL SYLLGVTILL NSVQPILSGV AVGSGWQAYV
AYINLGCYYV VGLPLGFLMG WVFHLGVMGI WGGMIFGGTA VQTVILAIIT VRCDWEKEAE
KAKVRVAKWS TPTLDDDESA AS
//
