ID A0A059EXP5_9MICR Unreviewed; 225 AA.
AC A0A059EXP5;
DT 09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT 09-JUL-2014, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=(d)CMP kinase {ECO:0000256|ARBA:ARBA00012906};
DE EC=2.7.4.25 {ECO:0000256|ARBA:ARBA00012906};
GN ORFNames=H312_02926 {ECO:0000313|EMBL:KCZ79685.1};
OS Anncaliia algerae PRA339.
OC Eukaryota; Fungi; Fungi incertae sedis; Microsporidia; Tubulinosematoidea;
OC Tubulinosematidae; Anncaliia.
OX NCBI_TaxID=1288291 {ECO:0000313|EMBL:KCZ79685.1, ECO:0000313|Proteomes:UP000030655};
RN [1] {ECO:0000313|Proteomes:UP000030655}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PRA339 {ECO:0000313|Proteomes:UP000030655};
RG The Broad Institute Genome Sequencing Platform;
RA Cuomo C., Becnel J., Sanscrainte N., Walker B., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KCZ79685.1, ECO:0000313|Proteomes:UP000030655}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PRA339 {ECO:0000313|EMBL:KCZ79685.1,
RC ECO:0000313|Proteomes:UP000030655};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Cuomo C., Becnel J., Sanscrainte N., Walker B., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Anncaliia algerae insect isolate PRA339.";
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + CMP = ADP + CDP; Xref=Rhea:RHEA:11600,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:58069, ChEBI:CHEBI:60377,
CC ChEBI:CHEBI:456216; EC=2.7.4.25;
CC Evidence={ECO:0000256|ARBA:ARBA00001097};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + dCMP = ADP + dCDP; Xref=Rhea:RHEA:25094,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:57566, ChEBI:CHEBI:58593,
CC ChEBI:CHEBI:456216; EC=2.7.4.25;
CC Evidence={ECO:0000256|ARBA:ARBA00001115};
CC -!- SIMILARITY: Belongs to the cytidylate kinase family. Type 1 subfamily.
CC {ECO:0000256|ARBA:ARBA00009427}.
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DR EMBL; KK365240; KCZ79685.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A059EXP5; -.
DR STRING; 1288291.A0A059EXP5; -.
DR VEuPathDB; MicrosporidiaDB:H312_02926; -.
DR HOGENOM; CLU_079959_0_0_1; -.
DR Proteomes; UP000030655; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004127; F:cytidylate kinase activity; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd02020; CMPK; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR HAMAP; MF_00238; Cytidyl_kinase_type1; 1.
DR InterPro; IPR003136; Cytidylate_kin.
DR InterPro; IPR011994; Cytidylate_kinase_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR00017; cmk; 1.
DR PANTHER; PTHR21299:SF2; CYTIDYLATE KINASE; 1.
DR PANTHER; PTHR21299; CYTIDYLATE KINASE/PANTOATE-BETA-ALANINE LIGASE; 1.
DR Pfam; PF02224; Cytidylate_kin; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000313|EMBL:KCZ79685.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000030655};
KW Transferase {ECO:0000313|EMBL:KCZ79685.1}.
FT DOMAIN 6..211
FT /note="Cytidylate kinase"
FT /evidence="ECO:0000259|Pfam:PF02224"
SQ SEQUENCE 225 AA; 25114 MW; 6EB2690FB8959594 CRC64;
MKNLIITIDG PAGAGKTDTA GMVGKKLNLI HYNSGYTYRA ITFALIKNNL INYEYDSDKV
RSFIRQINIK NIGNEVLLDC EKITDQLKSK EVDAFVPKVS KVAYIREKAK EILLEFATSG
VGLVVEGRDI GTVVLPNADV KIFLTASLEI RALRRFDQTA NSSYEDVFKG IKERDNIDTT
REIAPMKIPE NGFIVDNSYL TKSETAEQIV GITRGLMNIK SLDEE
//
