ID A0A059EZI2_9MICR Unreviewed; 1010 AA.
AC A0A059EZI2;
DT 09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT 09-JUL-2014, sequence version 1.
DT 22-FEB-2023, entry version 37.
DE RecName: Full=Importin N-terminal domain-containing protein {ECO:0000259|PROSITE:PS50166};
GN ORFNames=H312_02335 {ECO:0000313|EMBL:KCZ80277.1};
OS Anncaliia algerae PRA339.
OC Eukaryota; Fungi; Fungi incertae sedis; Microsporidia; Tubulinosematoidea;
OC Tubulinosematidae; Anncaliia.
OX NCBI_TaxID=1288291 {ECO:0000313|EMBL:KCZ80277.1, ECO:0000313|Proteomes:UP000030655};
RN [1] {ECO:0000313|Proteomes:UP000030655}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PRA339 {ECO:0000313|Proteomes:UP000030655};
RG The Broad Institute Genome Sequencing Platform;
RA Cuomo C., Becnel J., Sanscrainte N., Walker B., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KCZ80277.1, ECO:0000313|Proteomes:UP000030655}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PRA339 {ECO:0000313|EMBL:KCZ80277.1,
RC ECO:0000313|Proteomes:UP000030655};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Cuomo C., Becnel J., Sanscrainte N., Walker B., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Anncaliia algerae insect isolate PRA339.";
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the exportin family.
CC {ECO:0000256|ARBA:ARBA00009466}.
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DR EMBL; KK365191; KCZ80277.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A059EZI2; -.
DR STRING; 1288291.A0A059EZI2; -.
DR VEuPathDB; MicrosporidiaDB:H312_02335; -.
DR HOGENOM; CLU_011906_0_0_1; -.
DR Proteomes; UP000030655; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0005049; F:nuclear export signal receptor activity; IEA:InterPro.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0006611; P:protein export from nucleus; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR041235; Exp1_repeat_2.
DR InterPro; IPR013598; Exportin-1/Importin-b-like.
DR InterPro; IPR001494; Importin-beta_N.
DR InterPro; IPR045065; XPO1/5.
DR InterPro; IPR014877; XPO1_C_dom.
DR InterPro; IPR040485; XPO1_repeat_3.
DR PANTHER; PTHR11223; EXPORTIN 1/5; 1.
DR PANTHER; PTHR11223:SF2; EXPORTIN-1; 1.
DR Pfam; PF08767; CRM1_C; 1.
DR Pfam; PF18784; CRM1_repeat_2; 1.
DR Pfam; PF18787; CRM1_repeat_3; 1.
DR Pfam; PF03810; IBN_N; 1.
DR Pfam; PF08389; Xpo1; 1.
DR SMART; SM01102; CRM1_C; 1.
DR SMART; SM00913; IBN_N; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS50166; IMPORTIN_B_NT; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000030655};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 34..100
FT /note="Importin N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50166"
SQ SEQUENCE 1010 AA; 119343 MW; E918856891DDB88E CRC64;
MSEIFDFTKP LNVAALDRIV LEAFDPQNEK KEESEQILVE FKEHPNSWSR VDTILKESSN
PKTHFFALQI LENAVKTRWF LFSMEQRNGL KTYVVQFILE TSAQKENYIL KRFNIILVEI
LKKEWPKNWP SFISDLLNAS KTISMNVCRN SLEILKRLNE EIFEFSNDIT TSKKILLQNQ
FKTEYIQIFQ LIKAILESPN SMDSNLIETT FSAFISFCKK MGKEFLYNTN IIELICSYLN
SPHSISSIQC LREIIESNLE QIDIIDMNDS MVCDKFEKIN TNEENYVSKM ILMNREVVNF
CKLYMEKFNE VKIHKAFNEL DPLERDFIRE LAYFFSLFYE NNLLILEKHD LPTLKEGIEI
LTKFCRINDS RIFKKSIIFF NFFIINLYEE FPFNTQPKKV LRRDNYKNIL DSLIDIIVIK
MPRPEEVFVT VNEYGEVIKE KLTEVEKIEF FHKIKETLYH LASINQYSTK SYFFGKLDRL
LSNPTIFTHE HINHICWATG CISGSFSEEE EYNFFVTILK DLLALCEIKQ TKQDKAIIAS
NIIYIIGQYY RFLLSYLSFL KVLIKKIFEF LHEEHEGIKD MACDTFLRIC DKCSVKFPQM
EENKQNLVLW ILKHTKEITC DLEHYQKRII YQSFVKMIQN APLAHRAIYL DMLFNSFSDI
NILNPQFYAN FSFDDYTIKE TSHIIKSYSL VFKEMPDSSQ LCDKGVLPFL VDFYNKISTS
DFNKKSKELL KNDLINLFIS VIHKDTPNTF LDLIFKNVII DFKNEMKKNY LILNLGSEII
KNIEIDYNQE SFLIYQLINV STFNCDENVG LAMSYFSLVQ CFMSKRFNSF FNSIFSDSFF
NNFMDIIVNG LSSLKDVSDK CLELLNDLLV KLMDLKIYIF FKNYYFLLLE NIIGLLFDKD
KRFNFNLQVK TFCILIRVLS TCPPLGEGRD NYHFVGEFLI KMLCGCFPNL TKESVELFVT
GLFDLFTNER LFGEHVSDFR IKVYEFGTNE DYQDELNILQ LRKSQLLKEV
//
