ID A0A059IZ85_TRIIM Unreviewed; 808 AA.
AC A0A059IZ85;
DT 09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT 09-JUL-2014, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=DUF803 domain membrane protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=H109_07125 {ECO:0000313|EMBL:KDB20941.1};
OS Trichophyton interdigitale (strain MR816).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Arthrodermataceae; Trichophyton.
OX NCBI_TaxID=1215338 {ECO:0000313|EMBL:KDB20941.1, ECO:0000313|Proteomes:UP000024533};
RN [1] {ECO:0000313|EMBL:KDB20941.1, ECO:0000313|Proteomes:UP000024533}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MR816 {ECO:0000313|EMBL:KDB20941.1,
RC ECO:0000313|Proteomes:UP000024533};
RG The Broad Institute Genomics Platform;
RA Cuomo C.A., White T.C., Graser Y., Martinez-Rossi N., Heitman J.,
RA Young S.K., Zeng Q., Gargeya S., Abouelleil A., Alvarado L., Chapman S.B.,
RA Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C.,
RA Imamovic A., Larimer J., Martinez D., Murphy C., Pearson M.D.,
RA Persinoti G., Poon T., Priest M., Roberts A.D., Saif S., Shea T.D.,
RA Sykes S.N., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Trichophyton interdigitale MR816.";
RL Submitted (FEB-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KDB20941.1}.
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DR EMBL; AOKY01000649; KDB20941.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A059IZ85; -.
DR HOGENOM; CLU_012349_2_1_1; -.
DR OMA; VMQIRYI; -.
DR Proteomes; UP000024533; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015095; F:magnesium ion transmembrane transporter activity; IEA:InterPro.
DR InterPro; IPR008521; Mg_trans_NIPA.
DR PANTHER; PTHR12570:SF93; DUF803 DOMAIN MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G07070); 1.
DR PANTHER; PTHR12570; UNCHARACTERIZED; 1.
DR Pfam; PF05653; Mg_trans_NIPA; 1.
DR SUPFAM; SSF103481; Multidrug resistance efflux transporter EmrE; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000024533};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..16
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 17..808
FT /note="DUF803 domain membrane protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001578935"
FT TRANSMEM 53..76
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 208..228
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 234..254
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 263..281
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 301..319
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 326..343
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 355..374
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 395..414
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 100..182
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 449..808
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 123..151
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 486..514
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 539..555
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 610..624
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 646..662
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 737..775
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 789..808
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 808 AA; 87949 MW; 7D1816A94B9186ED CRC64;
MHVAFLLFLI AEQVSSTALP SPLHQSSFAA GNAPVLISEK PGEGGHGRDP ISEWSSTIGI
VTAIIGNVLI SVALNIQRYA HVRIEREYEG NILRLRAEWK RSSSPPRADG PTSSYSDYGA
VDRENARNQD DVGTSRYTDD PEEDGRRPRK AHTNGNGHAH AQSQENQSSE DEEADDPLQR
SFLSDRTATS FEKTIAGVDR KSYLRSSYWW FGIILMTVGE AGNFLAYGFA PASIVSPLGV
VALVSNCVIA PFMLKERFRQ RDFLGVVIAV AGAVIVVLSA KTSENKIGPD EIWGMITRWE
FETYLGITVV LIIALMSISR KYGRKTILID IGLVGLFGGY TALSTKGVSS LLSNTLWHAI
TFPITYVLVA VLVFSAVMQI RYINLALQHF NSTQVIPTQF VLFTLSVIMG SAILYRDFES
ATGERVAKFV GGCLLTFFAV YLITSGRTQK EDESESESET DEEEAIGLQN EEPYRDYVDW
QQDGAPIPRR QSTDSAGPGS KTKPSPSRSL QSLEEVYNES EDEDGQLTPR VRISASPGSL
LPPISSSSSI LDPSPLPAIS NPWATPSHER EEPDYLAATP GKDILSRSAD VYPPPTNVIL
QFPAAPGATD SPPRISPPQL GPQTPQGSPR RRSPTRAEQH STHKHSGQPL RTPGSVHRNS
LSRFSPGPLL PPLSGGLSAV VADSLRRGEG SPQQLRRSLR GSTRHKSKNR VRAGIPLYLD
AALDPRPVAE TENESAGTPR DGPQISRSTS TTGPDAFPSE HQRIRSLSDS WSGGLLNFGG
NLRLSGRRSK GKLPAENSEE PASRQPEP
//
