ID A0A059J4P9_TRIIM Unreviewed; 1106 AA.
AC A0A059J4P9;
DT 09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT 09-JUL-2014, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=R3H domain-containing protein {ECO:0000259|PROSITE:PS51061};
GN ORFNames=H109_05311 {ECO:0000313|EMBL:KDB22754.1};
OS Trichophyton interdigitale (strain MR816).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Arthrodermataceae; Trichophyton.
OX NCBI_TaxID=1215338 {ECO:0000313|EMBL:KDB22754.1, ECO:0000313|Proteomes:UP000024533};
RN [1] {ECO:0000313|EMBL:KDB22754.1, ECO:0000313|Proteomes:UP000024533}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MR816 {ECO:0000313|EMBL:KDB22754.1,
RC ECO:0000313|Proteomes:UP000024533};
RG The Broad Institute Genomics Platform;
RA Cuomo C.A., White T.C., Graser Y., Martinez-Rossi N., Heitman J.,
RA Young S.K., Zeng Q., Gargeya S., Abouelleil A., Alvarado L., Chapman S.B.,
RA Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C.,
RA Imamovic A., Larimer J., Martinez D., Murphy C., Pearson M.D.,
RA Persinoti G., Poon T., Priest M., Roberts A.D., Saif S., Shea T.D.,
RA Sykes S.N., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Trichophyton interdigitale MR816.";
RL Submitted (FEB-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the NFX1 family.
CC {ECO:0000256|ARBA:ARBA00007269}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KDB22754.1}.
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DR EMBL; AOKY01000337; KDB22754.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A059J4P9; -.
DR STRING; 1215338.A0A059J4P9; -.
DR HOGENOM; CLU_005714_2_1_1; -.
DR OMA; PRTSCED; -.
DR Proteomes; UP000024533; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd06008; NF-X1-zinc-finger; 5.
DR Gene3D; 3.30.1370.50; R3H-like domain; 1.
DR InterPro; IPR034078; NFX1_fam.
DR InterPro; IPR001374; R3H_dom.
DR InterPro; IPR036867; R3H_dom_sf.
DR InterPro; IPR000967; Znf_NFX1.
DR PANTHER; PTHR12360; NUCLEAR TRANSCRIPTION FACTOR, X-BOX BINDING 1 NFX1; 1.
DR PANTHER; PTHR12360:SF12; TRANSCRIPTIONAL REPRESSOR NF-X1; 1.
DR Pfam; PF01424; R3H; 1.
DR Pfam; PF01422; zf-NF-X1; 6.
DR SMART; SM00393; R3H; 1.
DR SMART; SM00438; ZnF_NFX; 9.
DR SUPFAM; SSF82708; R3H domain; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS51061; R3H; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000024533};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 878..941
FT /note="R3H"
FT /evidence="ECO:0000259|PROSITE:PS51061"
FT REGION 1..194
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 247..266
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1002..1033
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 969..1001
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1067..1098
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..23
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 55..79
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 122..151
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 247..264
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1010..1030
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1106 AA; 121396 MW; 02C0DF3AF6DC60DE CRC64;
MASSIDVPAS PTAASSSLGA QGRSRPQGDH RGSRRGRGSH RRGRGGRGDA HAVVNGTSQP
PQQQPQQQPQ QQPTTQEHPH EQQHQQRRSR GGRGWGRGRG ASHAGRSEVV TTRAFRGRLT
QPAESRHTNG QASQDQRHSA EAESSSSLRP DASEFVPGLS HKTPNPPEQS SSPSKQPRRH
PKKPTKTLTK SVADNITTRI HEDISNNLYE CPICTSELGP RSKVWSCRQC WTVFHLHCIK
KWSTNEGSVH TRPRDQEQED GSELPPARQW RCPGCNLPQD TLPSGYTCWC EKEMDIRSVP
GLPPHSCGQS CSRSREGCPH PCDSVCHAGP CAPCQAMGPV QSCYCGRHEI QKKCVDTDYV
SGWSCKETCE ELLPCLQHTC QRSCHEGLCG ECEELVPARC YCGKVTSQIL CNVKEEERES
RNQEETWIGS FTCPDVCGRL FDCGIHHCEK SCHPQDTLPS HCPTAPDMVS HCACGKTKLA
DMDVKPREAC TDSIPNCQKS CDKPLRCGHP CPKPCHTGPC PPCYLTMEVS CMCGRTTAKT
LCHQGKTEAP SCMRVCKATL NCGRHACGEH CCTGERKAIE RLATKKKLKS MNVRQTDEND
IEAEHICTRV CGKPLKCGTH ECQELCHRGP CARCPEAIFH EITCNCGRSV LYPPLPCGTG
PPACNFNCGR SKRCGHPQTP HNCHTDDESC PKCPFLMEKK CLCGKKVLKN QPCWLVDARC
GLVCGQELQC GSHTCKKECH RPGDCEDSIT SCQQQCGKIK KQCFHTCTEP CHAPFPCPEK
TPCQSKVTVT CQCGRIKQEK RCGATKDKDR QGHEAPSSLP CDEECGRIQR NRTIASAFGL
EVDPSSTATA SEPLTLENLP YSKETLDMYM ELASSSSLST METYESKLYE LARSMTDRST
RFPPARANFR AFVHSLAEDW GFKSESLDPE PHRHVVVFKS GGWLPPSLAG PGIGIRGISV
GDCAKFRDRE RLKERAAKRE AAAERARLEA ALKEAASASA NDGWAQVVSR KRPGTSSSPG
EASPYGFGTA TPSDSKGKLV LRSGIGLGRT VGSTSRFGAL GMDDADAHAD EDVAEDWEEE
VAREEQEMKE KMETMNVQHD GNSPSA
//
