ID A0A059J862_TRIIM Unreviewed; 1184 AA.
AC A0A059J862;
DT 09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT 09-JUL-2014, sequence version 1.
DT 22-FEB-2023, entry version 26.
DE RecName: Full=MIF4G domain-containing protein {ECO:0000259|SMART:SM00543};
GN ORFNames=H109_04250 {ECO:0000313|EMBL:KDB23868.1};
OS Trichophyton interdigitale (strain MR816).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Arthrodermataceae; Trichophyton.
OX NCBI_TaxID=1215338 {ECO:0000313|EMBL:KDB23868.1, ECO:0000313|Proteomes:UP000024533};
RN [1] {ECO:0000313|EMBL:KDB23868.1, ECO:0000313|Proteomes:UP000024533}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MR816 {ECO:0000313|EMBL:KDB23868.1,
RC ECO:0000313|Proteomes:UP000024533};
RG The Broad Institute Genomics Platform;
RA Cuomo C.A., White T.C., Graser Y., Martinez-Rossi N., Heitman J.,
RA Young S.K., Zeng Q., Gargeya S., Abouelleil A., Alvarado L., Chapman S.B.,
RA Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C.,
RA Imamovic A., Larimer J., Martinez D., Murphy C., Pearson M.D.,
RA Persinoti G., Poon T., Priest M., Roberts A.D., Saif S., Shea T.D.,
RA Sykes S.N., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Trichophyton interdigitale MR816.";
RL Submitted (FEB-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KDB23868.1}.
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DR EMBL; AOKY01000287; KDB23868.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A059J862; -.
DR STRING; 1215338.A0A059J862; -.
DR HOGENOM; CLU_002633_1_1_1; -.
DR OMA; DFQHHQI; -.
DR Proteomes; UP000024533; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:InterPro.
DR Gene3D; 1.25.40.180; -; 3.
DR Gene3D; 4.10.80.160; -; 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR003890; MIF4G-like_typ-3.
DR InterPro; IPR039762; Nmd2/UPF2.
DR InterPro; IPR007193; Upf2/Nmd2_C.
DR PANTHER; PTHR12839; NONSENSE-MEDIATED MRNA DECAY PROTEIN 2 UP-FRAMESHIFT SUPPRESSOR 2; 1.
DR PANTHER; PTHR12839:SF7; REGULATOR OF NONSENSE TRANSCRIPTS 2; 1.
DR Pfam; PF02854; MIF4G; 2.
DR Pfam; PF04050; Upf2; 1.
DR SMART; SM00543; MIF4G; 2.
DR SUPFAM; SSF48371; ARM repeat; 2.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000024533}.
FT DOMAIN 498..688
FT /note="MIF4G"
FT /evidence="ECO:0000259|SMART:SM00543"
FT DOMAIN 703..911
FT /note="MIF4G"
FT /evidence="ECO:0000259|SMART:SM00543"
FT REGION 170..213
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 260..288
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 438..491
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 935..1171
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 260..285
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 438..453
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 461..491
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 941..989
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 990..1035
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1054..1098
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1123..1149
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1150..1170
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1184 AA; 133987 MW; 2F22EC61F4A92C3C CRC64;
MERARKRELR DLNALVWAGE TDVFEVSKSL DSSLKKNTAF IKRLRTGITA AGLPTFITDV
RSLSLHKYLS EIISAFYEGL CKLKTPGEIA AGVEIASAIH QRFGPDEFTK RLAWNLGRGL
TSPDKAQLKA WTPEVREREE KERLSRHRVL LRVVTEFWLV GLLRSLDDVE RPDDSMPKCK
DSVPTLGGKG ADGSSKPRQS QSTKPNQDRD EEPFPLEVLK DLLGYDREHV NLPLALLFAR
TYSWDILGIK ALEEGRKTVE TNGTTTDTTP KEAQGGTSGD EAGTNTAQLD DAPLVPEKLQ
TRFKNVLNRY LEDVKKHVSR DQKALANQSR RNAEAYVKSG EILEDRQSNF EKQTKAHEKL
VSNTQSLCEI LGVEMPDLAE KDASDGAMSG SIGLVKTGEY LRGQGEGAGI WEDEEERRFY
ENLADFKGKV PAVLLEDGKK KKADGDDQSK VKPDAEGQNG TAAPEGTSKP DSQAADSSAR
EPEESATTIA NKSVGAQVDA LLSKLPELAN KDAVDQLALD FCFLNSKASR NRLVKAVQEV
PKGRSDLLPL YARLVATLGQ YLPDVPQGLI TYLDDEFRSL QRRKQKEFLG QVRTSNIRYL
AELTKFGVVP EHVIFHCFKV SLDEFSRMNI EIIGNLLENC GRYLLRNPET APRMASFLET
LGRKKSAQHL GQQERMIIEN AMYYVDPPQR PAIQQKERTP MELYIRKLIY LDMNKRNYTK
ILKAIRKLHW EEPEVVNILE RIFSKPGKIK YGNIHLLAII ISALYRYHQS FVIGVIDNVL
ERITIGLENN DFKFNQSRIS EVKYLGELYN YKMVDSPVIF DTLYRIVTYG HEGGTPSPGK
INPLDMPDDY FRIRLVCTIL DTCGVCFDRG SAKKKLDFFL TFFQYYLHTK DPIPMDVDFV
IQDTFALTRP QWKFAADFTE ATKLFAEAVA QNYQVQETDK APEPEDEEES SSSDEDIEDD
GAPDIEEVST DEAEVTANEP DDDNESESEE EQIFVSRQEE ERDPEAEAEF DRAFEKMVSE
SVESRKFERK TMFDVPLPMR RANPREPAQV EETKEPSPTP SSTMPFSLMT KRGNRQQTRT
IDLPSDSSFA VAMKTQQQAE REEQQRIKNL VLNYDLGDDN DSNDGDSNIS STHHFILRPN
TNAKGSLKGS DKRTSSHRDS RNDKSARSGF RARKLQLSDV DWYD
//
