ID A0A059J9E6_TRIIM Unreviewed; 2430 AA.
AC A0A059J9E6;
DT 09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT 09-JUL-2014, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=Carrier domain-containing protein {ECO:0000259|PROSITE:PS50075};
GN ORFNames=H109_04037 {ECO:0000313|EMBL:KDB24092.1};
OS Trichophyton interdigitale (strain MR816).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Arthrodermataceae; Trichophyton.
OX NCBI_TaxID=1215338 {ECO:0000313|EMBL:KDB24092.1, ECO:0000313|Proteomes:UP000024533};
RN [1] {ECO:0000313|EMBL:KDB24092.1, ECO:0000313|Proteomes:UP000024533}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MR816 {ECO:0000313|EMBL:KDB24092.1,
RC ECO:0000313|Proteomes:UP000024533};
RG The Broad Institute Genomics Platform;
RA Cuomo C.A., White T.C., Graser Y., Martinez-Rossi N., Heitman J.,
RA Young S.K., Zeng Q., Gargeya S., Abouelleil A., Alvarado L., Chapman S.B.,
RA Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C.,
RA Imamovic A., Larimer J., Martinez D., Murphy C., Pearson M.D.,
RA Persinoti G., Poon T., Priest M., Roberts A.D., Saif S., Shea T.D.,
RA Sykes S.N., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Trichophyton interdigitale MR816.";
RL Submitted (FEB-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KDB24092.1}.
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DR EMBL; AOKY01000279; KDB24092.1; -; Genomic_DNA.
DR STRING; 1215338.A0A059J9E6; -.
DR HOGENOM; CLU_000022_60_4_1; -.
DR OMA; ERSAWAI; -.
DR Proteomes; UP000024533; Unassembled WGS sequence.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR CDD; cd05918; A_NRPS_SidN3_like; 2.
DR CDD; cd19542; CT_NRPS-like; 2.
DR Gene3D; 3.30.300.30; -; 2.
DR Gene3D; 1.10.1200.10; ACP-like; 2.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 2.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 2.
DR Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 2.
DR InterPro; IPR010071; AA_adenyl_domain.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR001242; Condensatn.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR NCBIfam; TIGR01733; AA-adenyl-dom; 2.
DR PANTHER; PTHR45527:SF1; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR Pfam; PF00501; AMP-binding; 2.
DR Pfam; PF00668; Condensation; 2.
DR Pfam; PF00550; PP-binding; 2.
DR SMART; SM00823; PKS_PP; 2.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 2.
DR SUPFAM; SSF47336; ACP-like; 2.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 4.
DR PROSITE; PS00455; AMP_BINDING; 2.
DR PROSITE; PS50075; CARRIER; 2.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 1.
PE 4: Predicted;
KW Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000024533}.
FT DOMAIN 775..851
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 1865..1941
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT REGION 1851..1870
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1856..1870
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2430 AA; 269179 MW; 69F9A926A1785629 CRC64;
MDSAQVHSFN CTSTETRDDS IGKFPLLTDG YSPTCSKFEL ETKRHNICVE EGLTPGNLSE
SIVISAWALT LSIYIGSSNV SFHVLLNDES RWRTSMFHID ACENQTQQQF VQKSQNLLQK
LKSKSISNED VGDIELLEQP VNTAIVIGHV SSGSDLSTLK FVKKFIALDA MGPAVGTGFH
LNYQNSLLSD KQAMNVGSTF AKILSGFRQV SDRPLGSLEY MSQIHISQLW KFNSGSPKEP
WMECFHTIVE RHARGNPRSQ AIDAWDGIFT YAELNNLSII LAKYLQSHGV GPGSVVPISF
ERSAWAIVAM LSVSKAGGAF VSIPPYLPSG RREAMVQMIS PSILLTTSNF CHLWTTGPKC
IPIEGGRINC LPTSEMPLIT RSKPEDTFYI IFTSGSTGAP KGCMVSHSSF LNGALRNAPQ
WKFGPDRRVL QMLSHTFDMS LLEICTSLGS GACVCVPRTE EIEDSLADAI NKYKVSLAVM
TPSLARRLEP KAVPGLQVLC LGGESFPKEL VTLWSERINL FQFYGPSECS INSSTNAITH
KNTDPLNIGV PNNAACWVVS PEDYNKLVPI GAIGELLVSG AIVGQGYYKN PVKTAESFVQ
NVGFLQGDPH YSGWRCYRTG DLVRWNSDGT LVFCGRLDSQ VKLNGQRLEL GEVEYHLTLE
EEVGHAMAIV PGAGRCKDNL MGIISLKSPP PIDSKDKISV LPGALVDQNT QSIRKRLQNS
LPRYMVPTIW AYILRMPMSA SGKIDRVRVR RWVEEMSEST FREITGGIRQ PEDRKPLNKM
EQLIQGIWSA VLDLSTQDVG LHQSFIQLGG SSILAQEVVA KCRKEGIGLT MTDILTCNGI
AGAASLATAL GNNESQKRLL DSTSTQAWRK LQEKYDLSRL GVSHIEEVED VYPCTPMQIG
MFLGQIRKPG SYHLRFFYKP IVKGGKLPEL GRIKSAWHKV VSHHPSLRTV FVDDLGVGAE
YHSVVLRNTS VDVCIDEVSV NLSPSGAMDT FTKSIKPFAK RSTFHRISLC VCGDKVTYLM
IEMSHALADG AAMENLMRDF ATAFDDGQLL YQPQSHRDFV EYVASQNNEA SAKYWTSYLK
DCPPCMIPIS KQMIFDDLPT RFLRKDFVYE RSSDFLAKCK EKQITVASAV RVAWALVLRA
YIGSSDVCFT YVAAGRDVPV KDVHKMVGLC LSIQPCRAQL YSGSTFVSLA ERMQQDYIES
MPYQHYPLTE LKARLYPKGS EAMFNTAVSM EWTARTNPFY NTSIAFEEIR EQDDPTEYDI
VANVEIVDNI MKLGFLYWPS FSGIDVIHIA NAFKKALDCL LDSADKSVET ISLDGEHEFH
AMKTSDQESL DHTETCVFDA IEKQAMAQLN TQAVVSWDGE YSYGQLTEYY TTYAKYLVEQ
GINSGDIVVV CLDKSCWSVI TMLAILKAGA VFVATNPLHS QQRLENIVNH CHAKLIIVEP
RYSSLFETVD TSTVVVNKET VERALLSTTL PAIHDSDIAT IVYTSGTTGL PKGIIIDHGS
LSTSVLQGHG KRYGFDNQTR ALQFAAFTFD ACLQEIITVL SHGGCVCVPS EDERLSDLAG
CITQMHVNLA LFTPTVARLI RPQDVPCLKR IILCGEPMSR QDLEVWAGKV TLYNGYGPAE
ATICVSISGP LHVSDDPSNI GYAVEGTRLW ITEAADYNRL APVGCIGELV IESRQVSRGY
LHDVEKTTAM FINPAWLPGC RVYKTGDLAK RNPDGSLTYC GRKDTQVKLR GQRVELGEVE
YHVRECWTNA SGVVAEVIYP TGEEKATLAV FVCTGDAQKN ALSDLDGLEE PKNGVSPVWV
SKEFIEKLED RLPCYMVPSI FFTVPSIPLT LSGKTDRQQL RDIGSNFTSE QLSRVSDHQK
NSKRTPSGAR ERKLQQLWSS VLNVDKSQIS LDDSFFRLGG DSVSAMRLVT NARKSGINLT
VADVFRHPHI DEQARIASSS SKNILKTLIA KPFAHIQRKD LERVVSLVGL GPYAEIASDI
EDILPATDVQ SFYVSRAAES SRDALNYFYL RFDNTPDIAR LRHSCQGIVD QFPILRTIFI
STQGRTYQVV IRRLQVPFEI HNGVKNLSKA SDIFCLQDLE NKIVSGSLLL SFTLIRHVIS
GSQLIIRMSH AQYDGMSWPL ILRCLQESYA GVPRSPTQSF SSFISYTIGK VSESRKYWTN
LLQGSHMAQI SDKFRTETTL QRLEKTHVEK TVELPIPPKG ITVASLVSSA WSLVLRQITG
NRDVVYGFVV AGRNIGMPQI QEVVGPCMNT VPVRICFNSM RTTIDLQCHA MNQYLAMGDA
DSLGFQDIVE NCTQWPSGTK LDTLLQYHDI DETPVVTLSA GPGSEPCSAQ LDWFRKPYAA
PTNIEVSARP NGNTLGITLS SDGSLLSIDS AMAILTMFER SIRILSNGRA LPLDSINLLA
VTGRRNQSKI PDLCPPAYLT FQLLSLMFGS
//
