ID A0A059JAL5_TRIIM Unreviewed; 976 AA.
AC A0A059JAL5;
DT 09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT 09-JUL-2014, sequence version 1.
DT 13-SEP-2023, entry version 30.
DE RecName: Full=PXA domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=H109_03467 {ECO:0000313|EMBL:KDB24683.1};
OS Trichophyton interdigitale (strain MR816).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Arthrodermataceae; Trichophyton.
OX NCBI_TaxID=1215338 {ECO:0000313|EMBL:KDB24683.1, ECO:0000313|Proteomes:UP000024533};
RN [1] {ECO:0000313|EMBL:KDB24683.1, ECO:0000313|Proteomes:UP000024533}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MR816 {ECO:0000313|EMBL:KDB24683.1,
RC ECO:0000313|Proteomes:UP000024533};
RG The Broad Institute Genomics Platform;
RA Cuomo C.A., White T.C., Graser Y., Martinez-Rossi N., Heitman J.,
RA Young S.K., Zeng Q., Gargeya S., Abouelleil A., Alvarado L., Chapman S.B.,
RA Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C.,
RA Imamovic A., Larimer J., Martinez D., Murphy C., Pearson M.D.,
RA Persinoti G., Poon T., Priest M., Roberts A.D., Saif S., Shea T.D.,
RA Sykes S.N., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Trichophyton interdigitale MR816.";
RL Submitted (FEB-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the sorting nexin family.
CC {ECO:0000256|ARBA:ARBA00010883}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KDB24683.1}.
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DR EMBL; AOKY01000245; KDB24683.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A059JAL5; -.
DR STRING; 1215338.A0A059JAL5; -.
DR HOGENOM; CLU_007315_0_0_1; -.
DR OMA; INGWIIH; -.
DR Proteomes; UP000024533; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR CDD; cd06093; PX_domain; 1.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR InterPro; IPR003114; Phox_assoc.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR013937; Sorting_nexin_C.
DR PANTHER; PTHR22775:SF47; MEIOTICALLY UP-REGULATED GENE 122 PROTEIN; 1.
DR PANTHER; PTHR22775; SORTING NEXIN; 1.
DR Pfam; PF08628; Nexin_C; 1.
DR Pfam; PF00787; PX; 1.
DR Pfam; PF02194; PXA; 1.
DR SMART; SM00313; PXA; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR PROSITE; PS50195; PX; 1.
DR PROSITE; PS51207; PXA; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000024533};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 68..85
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 147..329
FT /note="PXA"
FT /evidence="ECO:0000259|PROSITE:PS51207"
FT DOMAIN 487..603
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
FT REGION 1..30
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 120..144
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 344..367
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 410..465
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 660..695
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 774..813
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 346..367
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 414..465
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 663..678
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 976 AA; 105212 MW; 5387F65CB1EC1201 CRC64;
MATKEDDTAV TASNESLAQP KSATVPPSST SQSLVDQVSL FVAHADGTTL ISISAGVVAV
SYVLFGRLAL LLVGAIGGVI LHIWWEGQDN GTNGDNEETA KRKRHELSLE VANRLTALYA
DNGSKQEDDE DPLNRSGEPS LDYSRMGPAT EAALTALTNS VIADYVSWWY KPILPSEDEF
PEACRNTLVS MVLAVSSRIS RKRPADMFLQ FATNSTSFMI VFFSELSAAV GTATTGSRPV
ADSIDEYLDK NPESSLANVL SSTQQEKKLG LVGTDILKTF LEPSVYNCGP LRIFLREVLS
RLILQPTIDM CSDAEYINTW IVYLLEQGEP QLLNAIDAGL EQADDVKQKN PTSTGTPTTN
VLEGKASNIV TNLGDQKLAE QMQPMRQPVD ANFAQHKDIS AVGMPKELPI SADSEETGGN
SAVYTHLPTD SSSSNTTDHQ PTPGSSTSLN EDSLDNPPID SQTTPILNTS ATSLITMQTS
QFHGSSVAII EDFNEDDKSN IRSKPTSEYL IQIEPSNSKL TGWMIARKYS DFEILHETLR
RISVVSGISD FSLQHNELPG WKGRNRNGLR ISLEKYLQAA LQYEQLAECE GMKKFLEKGR
QSGLEPESAS SKSGFPFAAP VAVFENVGKG VMGVLGTAPK GVANSKKVIV GGVSGIFGAS
GNDNRKRASS NAASRPTAVR GTSMDILPSP MTNVTAHSKN LSMSNLQDRP RTTFQRQPTH
LENESGDIGF GLPTSVTHAD SSLASSCEDL ADEGNVTPLS SSDTPDTVHV ALPSEANVES
NKELATRDIP ESASSGDVEP SPKKSSEGRS YAPVSEEEAV VVVELLFAVI NEVYSLSSAW
NIRKRLLNAS KSFLLRPGNP SLEAIRTLLQ DSIIDGNTSD EALAGYITKL RKSSLPTEED
MKAYPPPLSP EQKEQLRIKA RTLLISRGMP PALMGIMGAN ATGEALGKIF DCLQIPSVGR
AFVFAILLQA IRVMTQ
//
