ID A0A059JF95_TRIIM Unreviewed; 435 AA.
AC A0A059JF95;
DT 09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT 09-JUL-2014, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE RecName: Full=Endoplasmic reticulum-Golgi intermediate compartment protein {ECO:0000256|RuleBase:RU369013};
GN ORFNames=H109_01648 {ECO:0000313|EMBL:KDB26556.1};
OS Trichophyton interdigitale (strain MR816).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Arthrodermataceae; Trichophyton.
OX NCBI_TaxID=1215338 {ECO:0000313|EMBL:KDB26556.1, ECO:0000313|Proteomes:UP000024533};
RN [1] {ECO:0000313|EMBL:KDB26556.1, ECO:0000313|Proteomes:UP000024533}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MR816 {ECO:0000313|EMBL:KDB26556.1,
RC ECO:0000313|Proteomes:UP000024533};
RG The Broad Institute Genomics Platform;
RA Cuomo C.A., White T.C., Graser Y., Martinez-Rossi N., Heitman J.,
RA Young S.K., Zeng Q., Gargeya S., Abouelleil A., Alvarado L., Chapman S.B.,
RA Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C.,
RA Imamovic A., Larimer J., Martinez D., Murphy C., Pearson M.D.,
RA Persinoti G., Poon T., Priest M., Roberts A.D., Saif S., Shea T.D.,
RA Sykes S.N., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Trichophyton interdigitale MR816.";
RL Submitted (FEB-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Plays a role in transport between endoplasmic reticulum and
CC Golgi. {ECO:0000256|RuleBase:RU369013}.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|RuleBase:RU369013}; Multi-pass membrane protein
CC {ECO:0000256|RuleBase:RU369013}. Endoplasmic reticulum-Golgi
CC intermediate compartment membrane {ECO:0000256|RuleBase:RU369013};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU369013}. Golgi
CC apparatus membrane {ECO:0000256|RuleBase:RU369013}; Multi-pass membrane
CC protein {ECO:0000256|RuleBase:RU369013}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the ERGIC family.
CC {ECO:0000256|RuleBase:RU369013}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KDB26556.1}.
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DR EMBL; AOKY01000123; KDB26556.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A059JF95; -.
DR STRING; 1215338.A0A059JF95; -.
DR HOGENOM; CLU_034705_1_0_1; -.
DR OMA; QRHEGCR; -.
DR Proteomes; UP000024533; Unassembled WGS sequence.
DR GO; GO:0030134; C:COPII-coated ER to Golgi transport vesicle; IEA:UniProtKB-UniRule.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0033116; C:endoplasmic reticulum-Golgi intermediate compartment membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; IEA:UniProtKB-UniRule.
DR GO; GO:0006890; P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum; IEA:UniProtKB-UniRule.
DR InterPro; IPR045888; Erv.
DR InterPro; IPR012936; Erv_C.
DR InterPro; IPR039542; Erv_N.
DR PANTHER; PTHR10984; ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN; 1.
DR PANTHER; PTHR10984:SF25; ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN 3; 1.
DR Pfam; PF07970; COPIIcoated_ERV; 1.
DR Pfam; PF13850; ERGIC_N; 1.
PE 3: Inferred from homology;
KW Endoplasmic reticulum {ECO:0000256|RuleBase:RU369013};
KW ER-Golgi transport {ECO:0000256|RuleBase:RU369013};
KW Golgi apparatus {ECO:0000256|RuleBase:RU369013};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU369013};
KW Reference proteome {ECO:0000313|Proteomes:UP000024533};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU369013};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU369013}; Transport {ECO:0000256|RuleBase:RU369013}.
FT TRANSMEM 26..43
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU369013"
FT TRANSMEM 397..418
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU369013"
FT DOMAIN 8..96
FT /note="Endoplasmic reticulum vesicle transporter N-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF13850"
FT DOMAIN 143..419
FT /note="Endoplasmic reticulum vesicle transporter C-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF07970"
SQ SEQUENCE 435 AA; 48530 MW; AF4772A77DF36796 CRC64;
MAGKSRFTRL DAFAKTVEDA RIRTRSGGVV TIAALLIVIY LVWGEWKDYR RVVVQPELIV
DKGRGERMEI HLNMTFPNLP CELLTLDVMD VSGELQTDVD HGVNKVRLSS AAEGGKVIDV
TALALHKKED SPAHLDPNYC GDCYGVPAPS TAKKPGCCNT CDEVRDAYAE KNWAFGRGEN
VAQCIDEGYS QRIDEQRHEG CRIEGILRVN KVAGNFHIAP GRSLTAGNFH AHDLDNYYHT
PVPHTMSHII HKLRFGPQLP EELYSRWKWT HQDTINPLDK SEHKTNEARY NFLYFVKVVS
TSYLPLGWDP TLSSEAHSQA HRDIPLGNHG VFFGSQGSIE THQYSVTSHQ RSLDAEDASA
DGHKERQHAR GGIPSVMFNY DISPMKVINR ESRPKSLSAF FTGVCAVIGG TLTVAAAVDR
LLYEGSLRVK KLHKS
//
