ID A0A059LPF3_9CHLO Unreviewed; 681 AA.
AC A0A059LPF3;
DT 09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT 09-JUL-2014, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE RecName: Full=ATP-dependent DNA helicase {ECO:0000256|RuleBase:RU363044};
DE EC=3.6.4.12 {ECO:0000256|RuleBase:RU363044};
GN ORFNames=H632_c340p2 {ECO:0000313|EMBL:KDD76138.1};
OS Helicosporidium sp. ATCC 50920.
OC Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Trebouxiophyceae;
OC Chlorellales; Chlorellaceae; Helicosporidium.
OX NCBI_TaxID=1291522 {ECO:0000313|EMBL:KDD76138.1, ECO:0000313|Proteomes:UP000026042};
RN [1] {ECO:0000313|EMBL:KDD76138.1, ECO:0000313|Proteomes:UP000026042}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50920 {ECO:0000313|EMBL:KDD76138.1,
RC ECO:0000313|Proteomes:UP000026042};
RX PubMed=24809511;
RA Pombert J.F., Blouin N.A., Lane C., Boucias D., Keeling P.J.;
RT "A lack of parasitic reduction in the obligate parasitic green alga
RT helicosporidium.";
RL PLoS Genet. 10:E1004355-E1004355(2014).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|RuleBase:RU363044};
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|RuleBase:RU363044};
CC -!- SIMILARITY: Belongs to the helicase family.
CC {ECO:0000256|RuleBase:RU363044}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KDD76138.1}.
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DR EMBL; AYPS01000340; KDD76138.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A059LPF3; -.
DR STRING; 1291522.A0A059LPF3; -.
DR OrthoDB; 317209at2759; -.
DR Proteomes; UP000026042; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR GO; GO:0000723; P:telomere maintenance; IEA:InterPro.
DR CDD; cd18037; DEXSc_Pif1_like; 1.
DR CDD; cd18809; SF1_C_RecD; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR010285; DNA_helicase_pif1-like.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR049163; Pif1-like_2B_dom.
DR PANTHER; PTHR47642; ATP-DEPENDENT DNA HELICASE; 1.
DR PANTHER; PTHR47642:SF5; ATP-DEPENDENT DNA HELICASE; 1.
DR Pfam; PF05970; PIF1; 1.
DR Pfam; PF21530; Pif1_2B_dom; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|RuleBase:RU363044};
KW DNA damage {ECO:0000256|RuleBase:RU363044};
KW DNA recombination {ECO:0000256|RuleBase:RU363044};
KW DNA repair {ECO:0000256|RuleBase:RU363044};
KW Helicase {ECO:0000256|RuleBase:RU363044, ECO:0000313|EMBL:KDD76138.1};
KW Hydrolase {ECO:0000256|RuleBase:RU363044};
KW Nucleotide-binding {ECO:0000256|RuleBase:RU363044};
KW Reference proteome {ECO:0000313|Proteomes:UP000026042}.
FT DOMAIN 506..544
FT /note="DNA helicase Pif1-like 2B"
FT /evidence="ECO:0000259|Pfam:PF21530"
FT REGION 167..190
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 402..441
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 175..190
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 681 AA; 72840 MW; 6607A230DB41382D CRC64;
MSVIAQVRIE HSDPGSTAVR SEAGRSVLVE LHPPAFAGAA AELCVHLSKR KLQLAIAPPL
TVYAAGVAEG RLGLRFLRVR ASPGDRAYKT VQLSVQCTDV DGLRQLHARM ARFLGSGKEN
AGAVRPQTGK SSTLARVPLS SRSASVLNTP AFQPLSKPAS FSKPAFAACT GKNRSPPPRA
QTQPQEQFPL STEQRRALEA VASGRSLFFT GCAGTGKSHL LRAVLDSLPA HGTHVTGTTG
LAASALGGCT LASWAGTGRL DHGASFAELL AAASRGEAAR RWLAVRTLVV DEVSMLDGRW
FDALERLARE IRRDSRPWGG VQLVLSGDFH QLPPVSRDGS RVYCFEASTW GRVIKEQLTM
TQVFRQGEDL DFVHLLADVR RGVCTGEGVR ALRLRCRSLE NHGPGEEEER KQDQAGVERK
QDQAGVERKE DRAGATKTED QIDVIFKNDP AQPPFSLASA AIVSTKLMTH RQQVAEDNAR
QLAALPFPSR VFQAEDEGDV SLVRGACPAE SRLELKLGAQ VILVRTVCAA RGLVNGARGV
VVGFASAQGW PLVKFACLKA LKSASVVAAP IKTSGSLRPE SDPSVIAIAP ERWTVSCGGK
LVASRRQIPL ALGWALSIHK AQGLTLDSAE VDLSKAFEPG MAYVALSRVK SMDGLVIRGG
IAPTALEADP RVLSFYRGLE N
//
