ID   A0A059LR83_9CHLO        Unreviewed;       751 AA.
AC   A0A059LR83;
DT   09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT   09-JUL-2014, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   SubName: Full=Cullin {ECO:0000313|EMBL:KDD76676.1};
GN   ORFNames=H632_c141p1 {ECO:0000313|EMBL:KDD76676.1};
OS   Helicosporidium sp. ATCC 50920.
OC   Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Trebouxiophyceae;
OC   Chlorellales; Chlorellaceae; Helicosporidium.
OX   NCBI_TaxID=1291522 {ECO:0000313|EMBL:KDD76676.1, ECO:0000313|Proteomes:UP000026042};
RN   [1] {ECO:0000313|EMBL:KDD76676.1, ECO:0000313|Proteomes:UP000026042}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 50920 {ECO:0000313|EMBL:KDD76676.1,
RC   ECO:0000313|Proteomes:UP000026042};
RX   PubMed=24809511;
RA   Pombert J.F., Blouin N.A., Lane C., Boucias D., Keeling P.J.;
RT   "A lack of parasitic reduction in the obligate parasitic green alga
RT   helicosporidium.";
RL   PLoS Genet. 10:E1004355-E1004355(2014).
CC   -!- SIMILARITY: Belongs to the cullin family.
CC       {ECO:0000256|ARBA:ARBA00006019, ECO:0000256|PROSITE-ProRule:PRU00330,
CC       ECO:0000256|RuleBase:RU003829}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KDD76676.1}.
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DR   EMBL; AYPS01000141; KDD76676.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A059LR83; -.
DR   STRING; 1291522.A0A059LR83; -.
DR   OrthoDB; 21270at2759; -.
DR   Proteomes; UP000026042; Unassembled WGS sequence.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR   Gene3D; 1.20.1310.10; Cullin Repeats; 4.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR045093; Cullin.
DR   InterPro; IPR016158; Cullin_homology.
DR   InterPro; IPR036317; Cullin_homology_sf.
DR   InterPro; IPR001373; Cullin_N.
DR   InterPro; IPR019559; Cullin_neddylation_domain.
DR   InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR11932; CULLIN; 1.
DR   PANTHER; PTHR11932:SF126; CULLIN 4, ISOFORM A; 1.
DR   Pfam; PF00888; Cullin; 1.
DR   Pfam; PF10557; Cullin_Nedd8; 1.
DR   SMART; SM00182; CULLIN; 1.
DR   SMART; SM00884; Cullin_Nedd8; 1.
DR   SUPFAM; SSF75632; Cullin homology domain; 1.
DR   SUPFAM; SSF74788; Cullin repeat-like; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS50069; CULLIN_2; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000026042}.
FT   DOMAIN          397..626
FT                   /note="Cullin family profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50069"
FT   REGION          322..350
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        322..337
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   751 AA;  86353 MW;  6E5A5657CAA4AA1F CRC64;
     MAMVREGPIQ LEDGWRSMEE GIQRMKRILE GEQAEAFDSK HFMRLYTLIY NMCTQKPPCD
     HSEALYARYR RSIESYVTER VLPALRQTQD EGLLRELTKR WERHGVLVRW LSRFFQYLDR
     YFVQRQSLSS LKNVGLQVWR DNVYAEFHAK ARDATLRAVE AERRGEPADW ALLKNALSIF
     QEVGMGTLKR YEEDFEAAML EQTREYYRRA ALAWSEEGDG VGYLVRAEEA LRAEEERVNH
     YLHLSTKPKL LLQVETELLS KHQTSLLENA QGGCTALLKA GRKFDLTRMY RLFGRIPNGL
     NPMAVMFEKH VEEEGMRLVR EAGQAAEARK AKEAEGAPPR GSKGGPTPEH QFIRSVVDTH
     DAYGAYVSEC FGNSSLFHKS LKEAFETFCN KQVAGAPVAE LLASFCDGVL KKGGAERVGE
     EELEGLLDRA VRLLSYVSDK DLFSEFYRKK LAKRLLFTQT ASEEHERAVL TRLKQQCGAQ
     FTSKMEGMVN DLQLAREKER GFQDWRSGQP AGPALDLSVT VLTTGFWPTY KSLDLALPEE
     MMASLEQFSR FHDETTNKTR RLTWQLSLGT VHLRAQYDKA YEILVQPMQA AVLLALQAQD
     RMPYDALQAA TRLPPEDLDR ALGSLVLGKH KLLDKEPSGR RIGRQDVFFV NSKFSDRMRR
     IRIPLPPVDD RKKVQEEVDK DRKYAIDAAI VRIMKSRKTL SHSNLIAEVV QQLGRMFQAD
     VRVIKRSIEG LIDREYLERD ENNHNQYCYV V
//