ID A0A060HSI0_9ARCH Unreviewed; 269 AA.
AC A0A060HSI0;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE SubName: Full=Precorrin-4 C11-methyltransferase {ECO:0000313|EMBL:AIC16127.1};
DE EC=2.1.1.133 {ECO:0000313|EMBL:AIC16127.1};
GN Name=cobM {ECO:0000313|EMBL:AIC16127.1};
GN ORFNames=NVIE_018660 {ECO:0000313|EMBL:AIC16127.1};
OS Nitrososphaera viennensis EN76.
OC Archaea; Nitrososphaerota; Nitrososphaeria; Nitrososphaerales;
OC Nitrososphaeraceae; Nitrososphaera.
OX NCBI_TaxID=926571 {ECO:0000313|EMBL:AIC16127.1, ECO:0000313|Proteomes:UP000027093};
RN [1] {ECO:0000313|EMBL:AIC16127.1, ECO:0000313|Proteomes:UP000027093}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EN76 {ECO:0000313|EMBL:AIC16127.1};
RX PubMed=24907263; DOI=10.1099/ijs.0.063172-0;
RA Stieglmeier M., Klingl A., Alves R.J., Rittmann S.K., Melcher M.,
RA Leisch N., Schleper C.;
RT "Nitrososphaera viennensis gen. nov., sp. nov., an aerobic and mesophilic,
RT ammonia-oxidizing archaeon from soil and a member of the archaeal phylum
RT Thaumarchaeota.";
RL Int. J. Syst. Evol. Microbiol. 64:2738-2752(2014).
CC -!- PATHWAY: Cofactor biosynthesis; adenosylcobalamin biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004953}.
CC -!- SIMILARITY: Belongs to the precorrin methyltransferase family.
CC {ECO:0000256|ARBA:ARBA00005879}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP007536; AIC16127.1; -; Genomic_DNA.
DR RefSeq; WP_075054973.1; NZ_CP007536.1.
DR AlphaFoldDB; A0A060HSI0; -.
DR STRING; 926571.NVIE_018660; -.
DR GeneID; 74947130; -.
DR KEGG; nvn:NVIE_018660; -.
DR HOGENOM; CLU_011276_7_1_2; -.
DR OrthoDB; 6633at2157; -.
DR UniPathway; UPA00148; -.
DR Proteomes; UP000027093; Chromosome.
DR GO; GO:0046026; F:precorrin-4 C11-methyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-UniPathway.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd11641; Precorrin-4_C11-MT; 1.
DR InterPro; IPR000878; 4pyrrol_Mease.
DR InterPro; IPR035996; 4pyrrol_Methylase_sf.
DR InterPro; IPR014777; 4pyrrole_Mease_sub1.
DR InterPro; IPR014776; 4pyrrole_Mease_sub2.
DR InterPro; IPR006362; Cbl_synth_CobM/CibF.
DR InterPro; IPR003043; Uropor_MeTrfase_CS.
DR NCBIfam; TIGR01465; cobM_cbiF; 1.
DR PANTHER; PTHR45790:SF4; COBALT-PRECORRIN-4 C(11)-METHYLTRANSFERASE; 1.
DR PANTHER; PTHR45790; SIROHEME SYNTHASE-RELATED; 1.
DR Pfam; PF00590; TP_methylase; 1.
DR SUPFAM; SSF53790; Tetrapyrrole methylase; 1.
DR PROSITE; PS00839; SUMT_1; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:AIC16127.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000027093};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:AIC16127.1}.
FT DOMAIN 11..219
FT /note="Tetrapyrrole methylase"
FT /evidence="ECO:0000259|Pfam:PF00590"
SQ SEQUENCE 269 AA; 29486 MW; 041DF64FC333197D CRC64;
MQGNNNSNSK TVYFVGSGPG DPELITLKAK KLVEQADVII YSGSLFNPKN LKYARKDAVL
HDAALIDREK IYQILRDSAL EGKLAVRFHD GDPALFSTIR EQIDKLEADG ITCKVVPGVT
AILGAAADLK LEVTLPGITQ TLIITRAELR TPVPEREAIS ELAKHGATMA FYLSVHLIGD
VVKELLKGGV YTEQTPAAVV YRATWEDEKI IKGTLGDIAE KTKKEKIIKT ALIIVGDVIA
PKKYEHSKVY DAGFTHGYRK AENKNSNNK
//
