ID   A0A060PWW6_9RICK        Unreviewed;       919 AA.
AC   A0A060PWW6;
DT   03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT   03-SEP-2014, sequence version 1.
DT   24-JAN-2024, entry version 27.
DE   SubName: Full=Putative lipase {ECO:0000313|EMBL:BAP00188.1};
GN   ORFNames=WCLE_008960 {ECO:0000313|EMBL:BAP00188.1};
OS   Wolbachia endosymbiont of Cimex lectularius.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rickettsiales;
OC   Anaplasmataceae; Wolbachieae; Wolbachia.
OX   NCBI_TaxID=246273 {ECO:0000313|EMBL:BAP00188.1, ECO:0000313|Proteomes:UP000031663};
RN   [1] {ECO:0000313|EMBL:BAP00188.1, ECO:0000313|Proteomes:UP000031663}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=wCle {ECO:0000313|Proteomes:UP000031663};
RX   PubMed=24982177; DOI=10.1073/pnas.1409284111;
RA   Nikoh N., Hosokawa T., Moriyama M., Oshima K., Hattori M., Fukatsu T.;
RT   "Evolutionary origin of insect-Wolbachia nutritional mutualism.";
RL   Proc. Natl. Acad. Sci. U.S.A. 111:10257-10262(2014).
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DR   EMBL; AP013028; BAP00188.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A060PWW6; -.
DR   STRING; 246273.WCLE_008960; -.
DR   KEGG; wcl:WCLE_008960; -.
DR   HOGENOM; CLU_317109_0_0_5; -.
DR   OrthoDB; 7164496at2; -.
DR   Proteomes; UP000031663; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR   CDD; cd00519; Lipase_3; 1.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR002921; Fungal_lipase-like.
DR   PANTHER; PTHR45856; ALPHA/BETA-HYDROLASES SUPERFAMILY PROTEIN; 1.
DR   PANTHER; PTHR45856:SF11; LIPASE_3 DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF01764; Lipase_3; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        845..865
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        871..891
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          154..289
FT                   /note="Fungal lipase-like"
FT                   /evidence="ECO:0000259|Pfam:PF01764"
FT   REGION          1..54
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          486..571
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          609..630
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          649..729
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          811..838
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        13..46
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        489..565
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        653..667
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        679..727
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        818..838
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   919 AA;  101021 MW;  3EBA9B3C1FF94A83 CRC64;
     MANRTDLPNL SRVDLSTEED QKTTEIKDRC HSRDLGIERE EGPEILGGKS QETPAIPEDE
     LGDFQCSSFE SDTYEVIECD PNKIQIAGFS KQELLEMCNF CKISYGSNDE KLDSKYKIKA
     ELINEGYSII PFYYNERNKK CAGFVFTKDK EITIAYRGTK DFDDVMTDVS TAFTSEFLPE
     GGKMHDGFHN AFYDSLPSLG KILDGYAEEQ GSEIKDFRIN CTGHSMGAAL ATITALYLKK
     VKDAEYVRVA TFGSPRVFDF HGAEIYEKLL GENTIRVTNS SDPIPMFPSG SMGFKHVGKP
     LKIKTGNFVI NCFGMSFCIV GEYYHKTDTY YSCIQDIKPE DFQSNNSVSR YYYLSYVAAV
     PYYITTTALT IPYYLFPSAI SNTEQRYFER EMKFADDRRL MSLKDNKNGL VIHALGNAMV
     SLENPLIISH IECNINGRGE GLKFNIYDIA SFVNSNYHLN RNNMRLRQLC EIEDVPVKGV
     PNLIDAENHV PGSRNTISDL VNEPATSSRA VNEAGSKQLQ NPKPKSASSQ QPQKNAVDKG
     KNIMNNGHTS TKHLVSNNCK GGEMGNGNKN KSIKEKLSGA IKSIDPDTVE RLLNQEGTNI
     TESILKEALG QARERTKNSK ESGKKKQSQK NRLTKIIELL EAKLKSIGGA APSVDDSATT
     GSQVTPAAEP KESEEDQPDS SSLSPQSAVS GHSSSSSNFV NVPTSDEGGT ETSNGEHSQT
     PDSNNDSLSF EKIDEEPSVI LANSKGEDGQ RGSQPSLSLF NLPLPPASDN GLSKAIDDLD
     DWSKASDIID EEDIDNYDLS WLFLEEGEQI PHPENLEPEP TLSSTSKKSE QVNNTIPPNT
     KSSNLHIIAA SALAVAGIIL GVAIAVHLGM LAVGILVGAC CLVAAAVMYH YEWPSSFIET
     NKVEKVVPNE KKEPVATSA
//