ID A0A060Q3T1_9RICK Unreviewed; 590 AA.
AC A0A060Q3T1;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=Ribonuclease G {ECO:0000256|ARBA:ARBA00017719};
GN Name=rne {ECO:0000313|EMBL:BAO99629.1};
GN ORFNames=WCLE_003140 {ECO:0000313|EMBL:BAO99629.1};
OS Wolbachia endosymbiont of Cimex lectularius.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rickettsiales;
OC Anaplasmataceae; Wolbachieae; Wolbachia.
OX NCBI_TaxID=246273 {ECO:0000313|EMBL:BAO99629.1, ECO:0000313|Proteomes:UP000031663};
RN [1] {ECO:0000313|EMBL:BAO99629.1, ECO:0000313|Proteomes:UP000031663}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=wCle {ECO:0000313|Proteomes:UP000031663};
RX PubMed=24982177; DOI=10.1073/pnas.1409284111;
RA Nikoh N., Hosokawa T., Moriyama M., Oshima K., Hattori M., Fukatsu T.;
RT "Evolutionary origin of insect-Wolbachia nutritional mutualism.";
RL Proc. Natl. Acad. Sci. U.S.A. 111:10257-10262(2014).
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the RNase E/G family. RNase G subfamily.
CC {ECO:0000256|ARBA:ARBA00005663}.
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DR EMBL; AP013028; BAO99629.1; -; Genomic_DNA.
DR RefSeq; WP_041045338.1; NZ_AP013028.1.
DR AlphaFoldDB; A0A060Q3T1; -.
DR STRING; 246273.WCLE_003140; -.
DR KEGG; wcl:WCLE_003140; -.
DR HOGENOM; CLU_003468_5_1_5; -.
DR OrthoDB; 9804278at2; -.
DR Proteomes; UP000031663; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0004540; F:RNA nuclease activity; IEA:InterPro.
DR GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR CDD; cd04453; S1_RNase_E; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR Gene3D; 3.40.1260.20; Ribonuclease E, catalytic domain; 1.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR019307; RNA-bd_AU-1/RNase_E/G.
DR InterPro; IPR004659; RNase_E/G.
DR InterPro; IPR048583; RNase_E_G_thioredoxin-like.
DR InterPro; IPR003029; S1_domain.
DR NCBIfam; TIGR00757; RNaseEG; 1.
DR PANTHER; PTHR30001; RIBONUCLEASE; 1.
DR PANTHER; PTHR30001:SF1; RIBONUCLEASE E_G-LIKE PROTEIN, CHLOROPLASTIC; 1.
DR Pfam; PF10150; RNase_E_G; 1.
DR Pfam; PF20833; RNase_E_G_Thio; 1.
DR SMART; SM00316; S1; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
PE 3: Inferred from homology;
KW Cell inner membrane {ECO:0000256|ARBA:ARBA00022519};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884}.
FT DOMAIN 43..172
FT /note="S1 motif"
FT /evidence="ECO:0000259|SMART:SM00316"
FT REGION 102..126
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 590 AA; 66838 MW; 2F13B698F86FB413 CRC64;
MANSGKRLLL IENSICSDEV RVALSVNNRV VEFEQEFKEK RQLRGNIYIA HVKRVEPSLQ
AVFIEYGKNK QGFLSFSEIS PDYFNISEKE KEAFFESYSS GDCTEEGNGA SANTSSDSTT
SRSVNESGNG FVREVSLYRR YKLQDVISVN QKILVQLTKE ERGNKGASFT TYITLVGRYC
VFMPNSMSRG GVSRRIEDIN VRKQLKDILN SIELPKRSGL IVRTVGSGKS KKEIEQDYNY
LSSLWQNIQE NVSSVNVPSL IYNEADLIMK SIRDFCSNDV EVVISGKEAF ETVRQYARNV
LKGSKLRYRL YRGFVPIFTY YGIEDQISEL YSNRVKLPSG GSLIITLTEA FVSIDVNSGK
MTGEDSIEET AYRTNMEAAP EISRQVNLRG LSGLIVVDFI DMLKYQYCRA VESAIRQAFK
DDKARVQFSY INDFGLMVFS RQRIKPNIQE INTTECLHCK GIGKVKSNEV IVASILRDLQ
YVAIRNRNRS FDLVAHGSII AHIFNNKRDT VSTIEREFNI KLNVSADSNL SIDAFILKRG
DDVNLNDCKP LQNSGYKIET SNNERADNSG GLQSNFWLTK WLSRLLSSNS
//
