ID A0A060QLS5_9PROT Unreviewed; 1102 AA.
AC A0A060QLS5;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE SubName: Full=Cobalt-zinc-cadmium resistance protein CzcA Cation efflux system protein CusA {ECO:0000313|EMBL:CDG40587.1};
GN ORFNames=ASAP_2542 {ECO:0000313|EMBL:CDG40587.1};
OS Asaia bogorensis.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC Acetobacteraceae; Asaia.
OX NCBI_TaxID=91915 {ECO:0000313|EMBL:CDG40587.1, ECO:0000313|Proteomes:UP000027583};
RN [1] {ECO:0000313|EMBL:CDG40587.1, ECO:0000313|Proteomes:UP000027583}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SF2.1 {ECO:0000313|EMBL:CDG40587.1,
RC ECO:0000313|Proteomes:UP000027583};
RX PubMed=24682158; DOI=10.1093/gbe/evu062;
RA Chouaia B., Gaiarsa S., Crotti E., Comandatore F., Degli Esposti M.,
RA Ricci I., Alma A., Favia G., Bandi C., Daffonchio D.;
RT "Acetic acid bacteria genomes reveal functional traits for adaptation to
RT life in insect guts.";
RL Genome Biol. Evol. 6:912-920(2014).
RN [2] {ECO:0000313|EMBL:CDG40587.1, ECO:0000313|Proteomes:UP000027583}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SF2.1 {ECO:0000313|EMBL:CDG40587.1,
RC ECO:0000313|Proteomes:UP000027583};
RX PubMed=24804722; DOI=10.1371/journal.pone.0096566;
RA Degli Esposti M., Chouaia B., Comandatore F., Crotti E., Sassera D.,
RA Lievens P.M., Daffonchio D., Bandi C.;
RT "Evolution of mitochondria reconstructed from the energy metabolism of
RT living bacteria.";
RL PLoS ONE 9:e96566-e96566(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDG40587.1}.
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DR EMBL; CBLX010000021; CDG40587.1; -; Genomic_DNA.
DR RefSeq; WP_023979918.1; NZ_CBLX010000021.1.
DR AlphaFoldDB; A0A060QLS5; -.
DR eggNOG; COG0841; Bacteria.
DR Proteomes; UP000027583; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 3.30.70.1430; Multidrug efflux transporter AcrB pore domain; 2.
DR Gene3D; 3.30.70.1440; Multidrug efflux transporter AcrB pore domain; 2.
DR Gene3D; 3.30.70.1320; Multidrug efflux transporter AcrB pore domain like; 1.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 3.
DR InterPro; IPR027463; AcrB_DN_DC_subdom.
DR InterPro; IPR001036; Acrflvin-R.
DR PANTHER; PTHR32063; -; 1.
DR PANTHER; PTHR32063:SF34; MULTIDRUG RESISTANCE PROTEIN MDTC; 1.
DR Pfam; PF00873; ACR_tran; 2.
DR PRINTS; PR00702; ACRIFLAVINRP.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 338..355
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 362..379
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 391..412
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 433..454
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 460..483
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 535..555
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 915..933
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 940..960
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 966..992
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1013..1032
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1044..1069
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 1102 AA; 119735 MW; 42DE4DABF00F46DB CRC64;
MNLCRLFIMR PVATILLALS LLAAGAICYP LMPVANLPDI GSSTINIEIE QPGASPEQMV
SSVTTPLERY LGQIAGVKQI ESDSENSFAY IRVDFVESRN IDGALRDVQA ALRAARADLP
QGTLDRDPYA YKEDPTSQPV YLLSLTSDVM TLPKLYDLAQ IRVKPLLAQI KGVGHVQAVG
SADPAVRVDV NPYALYKWGV GFEDVRQALA SANANTPKGF IDSGGQRLML ETNDQAEHAA
QYRDLIIGYR NNLNPIKLSS VAEVTDSVQD LYQAGYFNNK RAITLIVRGQ PKANTVKIVD
AVKERMTVLR SVLPPGVQMD TAIDLSSSIR ASMDDTQLTL GVSIILVIGV ILVFLRRLRS
TIIPAVTVPI ALVGTIAVMK WEHFTLDIMS LMALTIAVGF VVDDAIVVLE NIARHMEAGM
DRMSASLRGS SEIGFTVLSI TASLIAVFIP LLFIPGQVGA IFFEFAMTIV SALLISLILS
LTLTPMMCAY WLDVEHEEPT GKTLRDRVLR AIDWALEGII SLYGRTLRVA LRHHVLTFLT
LPLSFVALVA SIVLMPKTGI PAQDIALVGG SISGDDTMSF NEITKRIHYV GAVMKDDPDV
LSVTSWNNSS SDGQLFARLS DKRTRTRTDT QIVESIRKKL GDMPGLRTSF FSAGDPNGGG
GQHRSGAFRY VLRDQDVAEL KLWVPRLVAR LRKEKMMSSV MTNIEGHGAS VHVKLRRDTE
ARYLVTPQLV GNVLYDAYGQ TVASRIHTEL TTHSVVMEVA RAYRESPEQL RNTWISTASG
TPAGAVRSNQ IRVRTAGGST ASTATQLSQA SLRNAIANQI TGNNSNGSAV ASSVETMIPL
INVADLVMEP TPMEIDHQDG MTSTAISFDL IDGKTYEDAR KLIEDTLRNM GAPAGLTGEF
SGLAGETKEM LVNELLAFMA ALFAMYIVLG ILYESLIHPF TILSTLPSAG IGAILGLWVG
GESFSLIAMI GMILLTGIVK KNAILMIDFA LYAEKELGHT PREAIYEACL TRFRPILMTT
LAAALGAVPL MTGHGYGSEM RRPLGIAIVG GMLISQLLTL YTTPVVYLYM DAIGRFGTRT
WHRIFPSRPA GRTVSTPLSS ES
//
